Small amounts of dietary fructose dramatically increase hepatic glucose uptake through a novel mechanism of glucokinase activation

Nutrition Reviews

Volumn 60, Issue 8, 2002, Pages 253-257

  Watford, Malcolm ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Fractose; Glucokinase; Glycogen storage; Hepatic glucose uptake

Indexed keywords

FRUCTOSE; FRUCTOSE 1 PHOSPHATE; GLUCOKINASE; GLUCOSE; INSULIN;

ENZYME ACTIVATION; ENZYME REGULATION; GLUCOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; GLYCOGEN METABOLISM; INSULIN BLOOD LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; REGULATORY MECHANISM; SHORT SURVEY;

DIET; ENZYME ACTIVATION; FRUCTOSE; GLUCOKINASE; GLUCOSE; HUMANS; LIVER;

CANIS FAMILIARIS;

EID: 0036322150     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1301/002966402320289377     Document Type: Short Survey

References (17)

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2. Current issues in fructose metabolism
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5. Regulation of fuel utilization
6. The glucose-6-phosphatase system
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8. The physiological role of glucokinase binding protein in hepatocytes
9. The nature and function of hexokinases in animal tissues
10. Short term control of glucokinase activity: Role of a regulatory protein
11. Fructose administration stimulates glucose phosphorylation in the livers of anesthetized rats
12. A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate
13. Investigation of the mechanism by which glucose analogues cause translocation of glucokinase in hepatocytes: Evidence for two glucose binding sites
14. Stimulation of glucose utilization by fructose in isolated rat hepatocytes
15. Small amounts of fructose markedly augment net hepatic glucose uptake in the conscious dog
16. Supplemental fructose attenuates postprandial glycemia in Zucker fatty fa/fa rats