Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites

Immunology

Volumn 130, Issue 3, 2010, Pages 363-373

  Kobori, Hiroko ^a   Hashiguchi, Masaaki ^a   Piao, Jinhua ^a   Kato, Moriyuki ^a   Ritprajak, Patcharee ^a   Azuma, Miyuki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Anti tumour immunity; B7 H3; Cytotoxic T lymphocyte; Effector function; Triggering receptor expressed on myeloid cell like transcript 2; Tumour infiltrating lymphocytes

Indexed keywords

ALLOANTIGEN; B7 ANTIGEN; CELL PROTEIN; MONOCLONAL ANTIBODY; OVALBUMIN; PROTEIN TLT 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GRAFT; CANCER GROWTH; CANCER INHIBITION; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR IMMUNITY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; INTERFERON-GAMMA; LECTINS, C-TYPE; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, NUDE; MICE, TRANSGENIC; NEOPLASMS; OVALBUMIN; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION;

EID: 77953523681     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03236.x     Document Type: Article

References (47)

1. Chapoval AI, Ni J, Lau JS et al. B7-H3: a costimulatory molecule for T cell activation and IFN-γ production. Nat Immunol 2001 2 : 269 274.
2. Sun JC, Bevan MJ. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003 300 : 339 342.
3. Zhang GB, Dong QM, Xu Y, Yu GH, Zhang XG. B7-H3: another molecule marker for Mo-DCs? Cell Mol Immunol 2005 2 : 307 311.
4. Kim J, Myers AC, Chen L et al. Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells. Am J Respir Cell Mol Biol 2005 33 : 280 289.
5. Saatian B, Yu XY, Lane AP, Doyle T, Casolaro V, Spannhake EW. Expression of genes for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation. Am J Physiol Lung Cell Mol Physiol 2004 287 : L217 25.
6. Nagai Y, Aso H, Ogasawara H et al. Anterior pituitary progenitor cells express costimulatory molecule 4Ig-B7-H3. J Immunol 2008 181 : 6073 6081.
7. Waschbisch A, Wintterle S, Lochmuller H, Walter MC, Wischhusen J, Kieseier BC, Wiendl H. Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions. Arthritis Rheum 2008 58 : 3600 3608.
8. Chen YW, Tekle C, Fodstad O. The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion. Curr Cancer Drug Targets 2008 8 : 404 413.
9. Ling V, Wu PW, Spaulding V, Kieleczawa J, Luxenberg D, Carreno BM, Collins M. Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Genomics 2003 82 : 365 377.
10. Sun M, Richards S, Prasad DV, Mai XM, Rudensky A, Dong C. Characterization of mouse and human B7-H3 genes. J Immunol 2002 168 : 6294 6297.
11. Zhou YH, Chen YJ, Ma ZY et al. 4IgB7-H3 is the major isoform expressed on immunocytes as well as malignant cells. Tissue Antigens 2007 70 : 96 104.
12. Tran CN, Thacker SG, Louie DM et al. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol 2008 180 : 2989 2998.
13. Prasad DV, Nguyen T, Li Z, Yang Y, Duong J, Wang Y, Dong C. Murine B7-H3 is a negative regulator of T cells. J Immunol 2004 173 : 2500 2506.
14. Suh WK, Gajewska BU, Okada H et al. The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol 2003 4 : 899 906.
15. Fukushima A, Sumi T, Fukuda K et al. B7-H3 regulates the development of experimental allergic conjunctivitis in mice. Immunol Lett 2007 113 : 52 7.
16. Zhang G, Xu Y, Lu X, Huang H, Zhou Y, Lu B, Zhang X. Diagnosis value of serum B7-H3 expression in non-small cell lung cancer. Lung Cancer 2009 : DOI:.
17. Chavin G, Sheinin Y, Crispen PL et al. Expression of immunosuppresive B7-H3 ligand by hormone-treated prostate cancer tumors and metastases. Clin Cancer Res 2009 15 : 2174 2180.
18. Roth TJ, Sheinin Y, Lohse CM et al. B7-H3 ligand expression by prostate cancer: a novel marker of prognosis and potential target for therapy. Cancer Res 2007 67 : 7893 7900.
19. Zang X, Thompson RH, Al-Ahmadie HA et al. B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome. Proc Natl Acad Sci USA 2007 104 : 19458 19463.
20. Castriconi R, Dondero A, Augugliaro R et al. Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. Proc Natl Acad Sci USA 2004 101 : 12640 12645.
21. Crispen PL, Sheinin Y, Roth TJ et al. Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clin Cancer Res 2008 14 : 5150 5157.
22. Sun Y, Wang Y, Zhao J, Gu M, Giscombe R, Lefvert AK, Wang X. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer 2006 53 : 143 151.
23. Wu CP, Jiang JT, Tan M et al. Relationship between co-stimulatory molecule B7-H3 expression and gastric carcinoma histology and prognosis. World J Gastroenterol 2006 12 : 457 459.
24. Sun X, Vale M, Leung E, Kanwar JR, Gupta R, Krissansen GW. Mouse B7-H3 induces antitumor immunity. Gene Ther 2003 10 : 1728 1734.
25. + cytolytic T cells. J Immunol 2004 173 : 5445 5450.
26. Lupu CM, Eisenbach C, Kuefner MA, Schmidt J, Lupu AD, Stremmel W, Encke J. An orthotopic colon cancer model for studying the B7-H3 antitumor effect in vivo. J Gastrointest Surg 2006 10 : 635 645.
27. Lupu CM, Eisenbach C, Lupu AD, Kuefner MA, Hoyler B, Stremmel W, Encke J. Adenoviral B7-H3 therapy induces tumor specific immune responses and reduces secondary metastasis in a murine model of colon cancer. Oncol Rep 2007 18 : 745 748.
28. Hashiguchi M, Kobori H, Ritprajak P, Kamimura Y, Kozono H, Azuma M. Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses. Proc Natl Acad Sci USA 2008 105 : 10495 10500.
29. King RG, Herrin BR, Justement LB. Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation. J Immunol 2006 176 : 6012 6021.
30. Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell 1994 76 : 17 27.
31. Otsuki N, Kamimura Y, Hashiguchi M, Azuma M. Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells. Biochem Biophys Res Commun 2006 344 : 1121 1127.
32. + T cells. J Immunol 2004 172 : 7306 7314.
33. + T cell-mediated apoptosis by CD137 (4-1BB) costimulation. Eur J Immunol 2001 31 : 1410 1416.
34. + T cells in murine acute graft-versus-host disease. J Immunol 2006 177 : 4281 4287.
35. + murine squamous cell carcinoma and the requirements of co-stimulatory molecules on tumour and host cells. Immunology 2000 101 : 541 547.
36. Piao J, Kamimura Y, Iwai H et al. Enhancement of T cell-mediated anti-tumor immunity via the ectopically expressed glucocorticoid-induced tumor necrosis factor receptor-related receptor ligand (GITRL) on tumors. Immunology 2009 127 : 489 499.
37. Chao TY, Chu TM. Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma. Cancer Immunol Immunother 1989 30 : 158 164.
38. Azuma M, Cayabyab M, Phillips JH, Lanier LL. Requirements for CD28-dependent T cell-mediated cytotoxicity. J Immunol 1993 150 : 2091 2101.
39. Lanier LL, O'Fallon S, Somoza C, Phillips JH, Linsley PS, Okumura K, Ito D, Azuma M. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 1995 154 : 97 105.
40. Nakajima A, Kodama T, Morimoto S et al. Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7. J Immunol 1998 161 : 1901 1907.
41. + T cells. Biochem Biophys Res Commun 2008 369 : 1134 1138.
42. Suh WK, Wang SX, Jheon AH et al. The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization. Proc Natl Acad Sci USA 2004 101 : 12969 12973.
43. Chen L, Ashe S, Brady WA, Hellstrom I, Hellstrom KE, Ledbetter JA, McGowan P, Linsley PS. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 1992 71 : 1093 1102.
44. Chen L, McGowan P, Ashe S, Johnston J, Li Y, Hellstrom I, Hellstrom KE. Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J Exp Med 1994 179 : 523 532.
45. + T lymphocytes in the P815 tumor system in vitro. J Immunol 1996 156 : 465 472.
46. Wang L, Fraser CC, Kikly K, Wells AD, Han R, Coyle AJ, Chen L, Hancock WW. B7-H3 promotes acute and chronic allograft rejection. Eur J Immunol 2005 35 : 428 438.
47. Nagashima O, Harada N, Usui Y, Yamazaki T, Yagita H, Okumura K, Takahashi K, Akiba H. B7-H3 contributes to the development of pathogenic Th2 cells in a murine model of asthma. J Immunol 2008 181 : 4062 4071.