Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions

Arthritis and Rheumatism

Volumn 58, Issue 11, 2008, Pages 3600-3608

  Waschbisch, Anne ^a,b   Wintterle, Sabine ^c,d   Lochmüller, Hanns ^e   Walter, Maggie C ^f   Wischhusen, Jörg ^a   Kieseier, Bernd C ^g   Wiendl, Heinz ^a,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^g HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; B7 HOMOLOG 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; DERMATOMYOSITIS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INCLUSION BODY MYOSITIS; MALE; MUSCLE BIOPSY; MUSCLE CELL; MYOBLAST; POLYMYOSITIS; PRIORITY JOURNAL; RHABDOMYOSARCOMA; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; BLOTTING, WESTERN; CD8-POSITIVE T-LYMPHOCYTES; DERMATOMYOSITIS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUSCLE CELLS; MUSCLE NEOPLASMS; MUSCULAR DISEASES; MYOSITIS, INCLUSION BODY; POLYMYOSITIS; RECEPTORS, IMMUNOLOGIC; RHABDOMYOSARCOMA; RNA, SMALL INTERFERING;

EID: 55849111880     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.23997     Document Type: Article

References (34)

1. Dalakas MC, Hohlfeld R. Polymyositis and dermatomyositis. Lancet 2003;362:971-82.
2. Vincent A. Unravelling the pathogenesis of myasthenia gravis. Nat Rev Immunol 2002;2:797-804.
3. Prud'homme GJ, Lawson BR, Chang Y, Theofilopoulos AN. Immunotherapeutic gene transfer into muscle. Trends Immunol 2001;22:149-55.
4. Emslie-Smith AM, Arahata K, Engel AG. Major histocompatibility complex class I antigen expression, immunolocalization of interferon subtypes, and T cell-mediated cytotoxicity in myopathies. Hum Pathol 1989;20:224-31.
5. Wiendl H, Lautwein A, Mitsdorffer M, Krause S, Erfurth S, Wienhold W, et al. Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies. J Neuroimmunol 2003; 138:132-43.
6. Wiendl H, Hohlfeld R, Kieseier BC. Immunobiology of muscle: advances in understanding an immunological microenvironment. Trends Immunol 2005;26:373-80.
7. Greenwald RJ, Freeman GJ, Sharpe AH. The B7 family revisited. Annu Rev Immunol 2005;23:515-48.
8. Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, Liu D, et al. B7-H3: a costimulatory molecule for T cell activation and IFN-γ production. Nat Immunol 2001;2:269-74.
9. Steinberger P, Majdic O, Derdak SV, Pfistershammer K, Kirchberger S, Klauser C, et al. Molecular characterization of human 4Ig-B7-H3, a member of the B7 family with four Ig-like domains. J Immunol 2004;172:2352-9.
10. Sun M, Richards S, Prasad DV, Mai XM, Rudensky A, Dong C. Characterization of mouse and human B7-H3 genes. J Immunol 2002;168:6294-7.
11. Zhou YH, Chen YJ, Ma ZY, Xu L, Wang Q, Zhang GB, et al. 4IgB7-H3 is the major isoform expressed on immunocytes as well as malignant cells. Tissue Antigens 2007;70:96-104.
12. Suh WK, Wang SX, Jheon AH, Moreno L, Yoshinaga SK, Ganss B, et al. The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization. Proc Natl Acad Sci U S A 2004;101:12969-73.
13. Saatian B, Yu XY, Lane AP, Doyle T, Casolaro V, Spannhake EW. Expression of genes for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation. Am J Physiol Lung Cell Mol Physiol 2004;287:L217-25.
14. Kim J, Myers AC, Chen L, Pardoll DM, Truong-Tran QA, Lane AP, et al. Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells. Am J Respir Cell Mol Biol 2005;33:280-9.
15. Petroff MG, Kharatyan E, Torry DS, Holets L. The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta. Am J Pathol 2005;167:465-73.
16. Sun Y, Wang Y, Zhao J, Gu M, Giscombe R, Lefvert AK, et al. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer 2006;53:143-51.
17. Wiendl H, Mitsdoerffer M, Schneider D, Melms A, Lochmuller H, Hohlfeld R, et al. Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies. Brain 2003;126:1026-35.
18. Dehmel T, Janke A, Hartung HP, Goebel HH, Wiendl H, Kieseier BC. The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies. Neurobiol Dis 2007;25: 665-74.
19. Dalakas MC. Polymyositis, dermatomyositis and inclusion-body myositis. N Engl J Med 1991;325:1487-98.
20. Askanas V, Engel WK, Mirabella M. Idiopathic inflammatory myopathies: inclusion-body myositis, polymyositis, and dermatomyositis. Curr Opin Neurol 1994;7:448-56.
21. Askanas V, Engel WK. Inclusion-body myositis: newest concepts of pathogenesis and relation to aging and Alzheimer disease. J Neuropathol Exp Neurol 2001;60:1-14.
22. Griggs RC, Askanas V, DiMauro S, Engel A, Karpati G, Mendell JR, et al. Inclusion body myositis and myopathies. Ann Neurol 1995;38:705-13.
23. Kieseier BC, Schneider C, Clements JM, Gearing AJ, Gold R, Toyka KV, et al. Expression of specific matrix metalloproteinases in inflammatory myopathies. Brain 2001;124:341-51.
24. Wiendl H, Mitsdoerffer M, Hofmeister V, Wischhusen J, Weiss EH, Dichgans J, et al. The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy. Brain 2003;126:176-85.
25. Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
26. Wang L, Fraser CC, Kikly K, Wells AD, Han R, Coyle AJ, et al. B7-H3 promotes acute and chronic allograft rejection. Eur J Immunol 2005;35:428-38.
27. + cytolytic T cells. J Immunol 2004;173:5445-50.
28. Sun X, Vale M, Leung E, Kanwar JR, Gupta R, Krissansen GW. Mouse B7-H3 induces antitumor immunity. Gene Ther 2003;10: 1728-34.
29. Suh WK, Gajewska BU, Okada H, Gronski MA, Bertram EM, Dawicki W, et al. The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol 2003;4:899-906.
30. Prasad DV, Nguyen T, Li Z, Yang Y, Duong J, Wang Y, et al. Murine B7-H3 is a negative regulator of T cells. J Immunol 2004;173:2500-6.
31. + regulatory T cells: role of B7-H3 expression and antigen presentation. Eur J Immunol 2007;37:2117-26.
32. Wiendl H, Hohlfeld R, Kieseier BC. Muscle-derived positive and negative regulators of the immune response. Curr Opin Rheumatol 2005;17:714-9.
33. Figarella-Branger D, Civatte M, Bartoli C, Pellissier JF. Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies. Muscle Nerve 2003;28:659-82.
34. Ferlazzo G, Semino C, Meta M, Procopio F, Morandi B, Melioli G. T lymphocytes express B7 family molecules following interaction with dendritic cells and acquire bystander costimulatory properties. Eur J Immunol 2002;32:3092-101.