SAMD4B, a novel SAM-containing protein, inhibits AP-1-,p53- and p21-mediated transcriptional activity

BMB Reports

Volumn 43, Issue 5, 2010, Pages 355-361

  Luo, Na ^a   Li, Guan ^a   Li, Yongqing ^a   Fan, Xiongwei ^a   Wang, Yuequn ^a   Ye, Xiangli ^a   Mo, Xiaoyan ^a   Zhou, Junmei ^a   Yuan, Wuzhou ^a   Tan, Ming ^a   Xie, Huaping ^a   Ocorr, Karen ^a   Bodmer, Rolf ^a   Deng, Yun ^a   Wu, Xiushan ^a  

^a Key Lab of MOE for Development Biology and Protein Chemistry   (China)

Author keywords

AP 1; p21; p53; SAM protein; SAMD4B

Indexed keywords

MAMMALIA;

EID: 77953521331     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/bmbrep.2010.43.5.355     Document Type: Article

References (25)

1. Levine, A. J., Hu, W. and Feng, Z. (2006) The P53 pathway: what questions remain to be explored? Cell Death Differ. 13, 1027-1036.
2. Giaccia, A. J. and Kastan, M. B. (1998) The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983.
3. Harris, S. L. and Levine, A. J. (2005) The p53 pathway: positive and negative feedback loops. Oncogene 24, 2899-2908.
4. Shaulian, E. and Karin, M. (2001) AP-1 in cell proliferation and survival. Oncogene 20, 2390-2400.
5. Zhang, J., Zhang, D., Mcquade, J. S., Behbehani, M., Tsien, J. Z. and Xu, M. (2002) c-fos regulates neuronal excitability and survival. Nat. Genet. 30, 416-420.
6. Gorospe, M., Ciriell, C., Wang, X., Seth, P., Capogrossi, M. C. and Holbrook, N. J. (1997) p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene 14, 929-935.
7. Niculescu, A. B., Chen, X., Smeets, M., Hengst, L., Prives, C. and Reed, S. I. (1998) Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell Biol. 18, 629-634.
8. Schultz, J., Ponting, C. P., Hofmann, K. and Bork, P. (1997) SAM as a protein interaction domain involved in developmental regulation. Protein. Sci. 6, 249-253.
9. Thanos, C. D., Goodwill, K. E. and Bowie, J. U. (1999) Oligomeric structure of the human EphB2 receptor SAM domain. Science 283, 833-836.
10. Ponting, C. P. (1995) SAM: a novel motif in yeast sterile and Drosophila polyhomeotic proteins. Protein Sci. 4, 1928-1930.
11. Asher, G., Tsvetkov, P., Kahana, C. and Shaul, Y. (2005) A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73. Genes Dev. 19, 316-321.
12. Barrera, F. N., Poveda, J. A., González-Ros, J. M. and Neira, J. L. (2003) Binding of the C-terminal Sterile_Motif (SAM) Domain of Human p73 to Lipid Membranes. J. Biol. Chem. 278, 46878-46885.
13. Hu, J. J., Yuan, W. Z., Tang, M., Wang, Y. Q., Fan, X. W., Mo, X. Y., Li, Y. Q., Ying, Z. C., Wan, Y. Q., Ocorr, K., Bodmer, R., Deng, Y. and Wu, X. S. (2010) KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1. BMB Rep. 43, 17-22.
14. Ghioni, P., Bolognese, F., Duijf, P. H., Van Bokhoven, H., Mantovani, R. and Guerrini, L. (2002) Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol. Cell Biol. 22, 8659-8668.
15. Koutsodontis, G., Tentes, I., Papakosta, P., Moustakas, A., and Kardassis, D. (2001) Sp1 Plays a Critical Role in the Transcriptional Activation of the Human Cyclin-dependent Kinase Inhibitor p21WAF1/Cip1 Gene by the p53 tumor suppressor protein. J. Biol. Chem. 276, 29116-29125.
16. Stepniak, E., Ricci, R., Eferl, R., Sumara, G., Sumara, I., Rath, M., Hui, L. and Wagner, E. F. (2006) c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. Genes Dev. 20, 2306-2314.
17. Elkeles, A., Juven-Gershon, T., Israeli, D., Wilder, S., Zalcenstein, A. and Oren, M. (1999) The c-fos protooncogene is a target for transactivation by the p53 tumor sup-pressor. Mol. Cell Biol. 19, 2594-2600.
18. Miled, C., Pontoglio, M., Garbay, S., Yaniv, M. and Weitzman, J. B. (2005) A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network. Cancer Res. 65, 5096-5104.
19. Luo, K., Yuan, W. Z., Pi, H., Li, Y. Q., Zhu, C., Zhou, L., Jiao, W., Wang, Y. Q., Wu, X. S. and Liu, M. Y. (2002) Expression of a novel Krüpple-like zincfinger gene, ZNF382, in human heart. Biochem. Biophys. Res. Commun. 299, 606-612.
20. Zhou, L., Zhu, C. B., Luo, K. M., Li, Y. Q., Pi, H. L., Yuan, W. Z., Wang, Y. Q., Huang, C., Liu, M. Y. and Wu, X. S. (2002) Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development. Biochem. Biophys. Res. Commun. 295, 862-868.
21. Wang, Y., Li, Y., Zeng, W., Zhu, C., Xiao, J., Yuan, W., Wang, Y., Cai, Z., Zhou, J., Liu, M. and Wu, X. (2004) IXL, a new subunit of the mammalian Mediator complex, functions as a transcriptional suppressor. Biochem. Biophys. Res. Commun. 325, 1330-1338.
22. Cheng, Y., Wang, Y., Li, Y., Deng, Y., Hu, J., Mo, X., Li, N., Li, Y., Luo, N., Yuan, W., Xiao, J., Zhu, C., Wu, X. and Liu, M. (2006) A novel human gene ZNF415 with five isoforms inhibits AP-1- and p53-mediated transcriptional activity. Biochem. Biophys. Res. Commun. 351, 33-39.
23. Deng, Y., Liu, B. S., Fan, X. W., Wang, T. Q., Tang, M., Mo, X. Y., Li, Y. Q., Ying, Z. C., Wan, Y. Q., Luo, N., Zhou, J. M., Wu, X. S. and Yuan, W. Z. (2010) ZNF552, a novel human KRAB/C2H2 zinc finger protein, inhibits AP-1 and SRE-mediated transcriptional activity. BMB Rep. 43, 212-218.
24. Xia, C., Ma, W., Stafford, L. J., Marcus, S., Xiong, W. C. and Liu, M. (2001) Regulation of the p21-activated kinase (PAK) by a human G-beta-like WD-repeat protein, hPIP1. Proc. Natl. Acad. Sci. 98, 6174-6179.
25. Zhao, Y. L., Zhou, L., Liu, B. S., Deng, Y., Wang, Y., Wang, Y. Q., Huang, W., Yuan, W. Z., Wang, Z., Zhu, C. B., Liu, M. Y., Wu, X. S. and Li, Y. Q. (2006) ZNF325, a novel human zinc finger protein with a RBaK-like RB-binding domain, inhibits AP-1- and SRE-mediated transcriptional activity. Biochem. Biophys. Res. Commun. 346, 1191-1199.