메뉴 건너뛰기




Volumn 113, Issue 1, 2010, Pages 9-13

Novel etiological and therapeutic strategies for neurodiseases: RNA editing enzyme abnormality in sporadic amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis (ALS); Cytoplasmic fragile X mental retardation protein interacting protein 2 (CYFIP2); GluR2 Q R; Neurodisease; RNA editing; amino 3 hydroxy 5 methyl 4 isoxazolepropionate (AMPA) receptor

Indexed keywords

ADAR2 PROTEIN; ADENOSINE DEAMINASE; AMPA RECEPTOR; CYTOPLASMIC FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 2; FRAGILE X MENTAL RETARDATION PROTEIN; MESSENGER RNA; RNA; UNCLASSIFIED DRUG;

EID: 77953517354     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09R21FM     Document Type: Review
Times cited : (9)

References (38)
  • 1
    • 0030780350 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: Analysis of 155 cases and identification of a novel insertion mutation
    • Jackson M, Al-Chalabi A, Enayat ZE, Chioza B, Leigh PN, Morrison KE. Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: analysis of 155 cases and identification of a novel insertion mutation. Ann Neurol. 1997;42:803-807.
    • (1997) Ann Neurol , vol.42 , pp. 803-807
    • Jackson, M.1    Al-Chalabi, A.2    Enayat, Z.E.3    Chioza, B.4    Leigh, P.N.5    Morrison, K.E.6
  • 3
    • 0031307181 scopus 로고    scopus 로고
    • Are age-related neurodegenerative diseases linked with various types of magnesium depletion?
    • Durlach J, Bac P, Durlach V, Durlach A, Bara M, Guiet-Bara A. Are age-related neurodegenerative diseases linked with various types of magnesium depletion? Magnes Res. 1997;10:339-353.
    • (1997) Magnes Res , vol.10 , pp. 339-353
    • Durlach, J.1    Bac, P.2    Durlach, V.3    Durlach, A.4    Bara, M.5    Guiet-Bara, A.6
  • 4
    • 0019451969 scopus 로고
    • Humoral immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia
    • Hoffman PM, Robbins DS, Oldstone MB, Gibbs CJ Jr, Gajdusek DC. Humoral immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia. Ann Neurol. 1981;10:193-196.
    • (1981) Ann Neurol , vol.10 , pp. 193-196
    • Hoffman, P.M.1    Robbins, D.S.2    Oldstone, M.B.3    Gibbs Jr., C.J.4    Gajdusek, D.C.5
  • 6
    • 0036796276 scopus 로고    scopus 로고
    • Role of oxidative stress and antioxidants in neurodegenerative diseases
    • Rao AV, Balachandran B. Role of oxidative stress and antioxidants in neurodegenerative diseases. Nutr Neurosci. 2002;5:291-309.
    • (2002) Nutr Neurosci , vol.5 , pp. 291-309
    • Rao, A.V.1    Balachandran, B.2
  • 7
    • 0026556258 scopus 로고
    • Alterations in spinal cord excitatory amino acid receptors in amyotrophic lateral sclerosis patients
    • Allaoua H, Chaudieu I, Krieger C, Boksa P, Privat A, Quirion R. Alterations in spinal cord excitatory amino acid receptors in amyotrophic lateral sclerosis patients. Brain Res. 1992;579:169-172.
    • (1992) Brain Res , vol.579 , pp. 169-172
    • Allaoua, H.1    Chaudieu, I.2    Krieger, C.3    Boksa, P.4    Privat, A.5    Quirion, R.6
  • 8
    • 0033993642 scopus 로고    scopus 로고
    • AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability
    • Vandenberghe W, Robberecht W, Brorson J. AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability. J Neurosci. 2000;20:123-132.
    • (2000) J Neurosci , vol.20 , pp. 123-132
    • Vandenberghe, W.1    Robberecht, W.2    Brorson, J.3
  • 9
    • 0029113872 scopus 로고
    • Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity
    • Rothstein JD, Kuncl RW. Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity. J Neurochem. 1995;65:643-651.
    • (1995) J Neurochem , vol.65 , pp. 643-651
    • Rothstein, J.D.1    Kuncl, R.W.2
  • 10
    • 33745460795 scopus 로고    scopus 로고
    • Calcium-permeable AMPA channels in neurodegenerative disease and ischemia
    • Kwak S, Weiss JH. Calcium-permeable AMPA channels in neurodegenerative disease and ischemia. Curr Opin Neurobiol. 2006; 16:281-287.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 281-287
    • Kwak, S.1    Weiss, J.H.2
  • 11
    • 26444513243 scopus 로고    scopus 로고
    • Excitotoxicity and ALS: What is unique about the AMPA receptors expressed on spinal motor neurons?
    • Kawahara Y, Kwak S. Excitotoxicity and ALS: what is unique about the AMPA receptors expressed on spinal motor neurons? Amyotroph Lateral Scler Other Motor Neuron Disord. 2005;6: 131-144.
    • (2005) Amyotroph Lateral Scler Other Motor Neuron Disord , vol.6 , pp. 131-144
    • Kawahara, Y.1    Kwak, S.2
  • 12
    • 0032752054 scopus 로고    scopus 로고
    • Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis
    • Takuma H, Kwak S, Yoshizawa T, Kanazawa I. Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis. Ann Neurol. 1999;46:806-815.
    • (1999) Ann Neurol , vol.46 , pp. 806-815
    • Takuma, H.1    Kwak, S.2    Yoshizawa, T.3    Kanazawa, I.4
  • 14
    • 15044346521 scopus 로고    scopus 로고
    • Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
    • Kwak S, Kawahara Y. Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. J Mol Med. 2005;83: 110-120.
    • (2005) J Mol Med , vol.83 , pp. 110-120
    • Kwak, S.1    Kawahara, Y.2
  • 15
    • 0034612640 scopus 로고    scopus 로고
    • Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2
    • Higuchi M, Maas S, Single F, Hartner J, Rozov A, Burnashev N, et al. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature. 2000;406:78-81.
    • (2000) Nature , vol.406 , pp. 78-81
    • Higuchi, M.1    Maas, S.2    Single, F.3    Hartner, J.4    Rozov, A.5    Burnashev, N.6
  • 16
    • 0026543243 scopus 로고
    • Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
    • Burnashev N, Monyer H, Seeburg P, Sakmann B. Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron. 1992;8:189-198.
    • (1992) Neuron , vol.8 , pp. 189-198
    • Burnashev, N.1    Monyer, H.2    Seeburg, P.3    Sakmann, B.4
  • 17
    • 0027339892 scopus 로고
    • Determinants of Ca 2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing
    • Köhler M, Burnashev N, Sakmann B, Seeburg P. Determinants of Ca 2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron. 1993; 10:491-500.
    • (1993) Neuron , vol.10 , pp. 491-500
    • Köhler, M.1    Burnashev, N.2    Sakmann, B.3    Seeburg, P.4
  • 18
    • 0028598361 scopus 로고
    • Extent of RNA editing of glutamate receptor subunit GluR5 in different brain regions of the rat
    • Paschen W, Djuricic B. Extent of RNA editing of glutamate receptor subunit GluR5 in different brain regions of the rat. Cell Mol Neurobiol. 1994;14:259-270.
    • (1994) Cell Mol Neurobiol , vol.14 , pp. 259-270
    • Paschen, W.1    Djuricic, B.2
  • 19
    • 0029015346 scopus 로고
    • Temporal analysis of the upregulation of GluR5 mRNA editing with age: Regional evaluation
    • Paschen W, Schmitt J, Dux E, Djuricic B. Temporal analysis of the upregulation of GluR5 mRNA editing with age: regional evaluation. Brain Res Dev Brain Res. 1995;86:359-363.
    • (1995) Brain Res Dev Brain Res , vol.86 , pp. 359-363
    • Paschen, W.1    Schmitt, J.2    Dux, E.3    Djuricic, B.4
  • 20
    • 0028831719 scopus 로고
    • Regional differences in the extent of RNA editing of the glutamate receptor subunits GluR2 and GluR6 in rat brain
    • Paschen W, Djuricic B. Regional differences in the extent of RNA editing of the glutamate receptor subunits GluR2 and GluR6 in rat brain. J Neurosci Methods. 1995;56:21-29.
    • (1995) J Neurosci Methods , vol.56 , pp. 21-29
    • Paschen, W.1    Djuricic, B.2
  • 21
    • 0029671398 scopus 로고    scopus 로고
    • Regional analysis of developmental changes in the extent of GluR6 mRNA editing in rat brain
    • Schmitt J, Dux E. Gissel C, Paschen W. Regional analysis of developmental changes in the extent of GluR6 mRNA editing in rat brain. Brain Res DevelopBrain Res. 1996;91:153-157.
    • (1996) Brain Res DevelopBrain Res , vol.91 , pp. 153-157
    • Schmitt, J.1    Dux, E.2    Gissel, C.3    Paschen, W.4
  • 22
    • 0033047590 scopus 로고    scopus 로고
    • Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: Evidence for independent developmental, pathological and cellular regulation
    • Bernard A, Ferhat L, Dessi F, Charton G, Represa A, Ben-Ari Y, et al. Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: evidence for independent developmental, pathological and cellular regulation. Eur J Neurosci. 1999;11:604-616.
    • (1999) Eur J Neurosci , vol.11 , pp. 604-616
    • Bernard, A.1    Ferhat, L.2    Dessi, F.3    Charton, G.4    Represa, A.5    Ben-Ari, Y.6
  • 23
    • 0041666420 scopus 로고    scopus 로고
    • Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain
    • Kawahara Y, Ito K, Sun H, Kanazawa I, Kwak S. Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain. Eur J Neurosci. 2003;18:23-33.
    • (2003) Eur J Neurosci , vol.18 , pp. 23-33
    • Kawahara, Y.1    Ito, K.2    Sun, H.3    Kanazawa, I.4    Kwak, S.5
  • 24
    • 0742281369 scopus 로고    scopus 로고
    • Glutamate receptor RNA editing: A molecular analysis of GluR2, GluR5 and GluR6 in human brain tissues and in NT2 cells following in vitro neural differentiation
    • Barbon A, Vallini I, La Via L, Marchina E, Barlati S. Glutamate receptor RNA editing: a molecular analysis of GluR2, GluR5 and GluR6 in human brain tissues and in NT2 cells following in vitro neural differentiation. Brain Res Mol Brain Res. 2003;117:168-178.
    • (2003) Brain Res Mol Brain Res , vol.117 , pp. 168-178
    • Barbon, A.1    Vallini, I.2    la Via, L.3    Marchina, E.4    Barlati, S.5
  • 25
    • 0034984132 scopus 로고    scopus 로고
    • RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients
    • Kortenbruck G, Berger E, Speckmann EJ, Musshoff U. RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients. Neurobiol Dis. 2001;8:459-468.
    • (2001) Neurobiol Dis , vol.8 , pp. 459-468
    • Kortenbruck, G.1    Berger, E.2    Speckmann, E.J.3    Musshoff, U.4
  • 26
    • 12744273085 scopus 로고    scopus 로고
    • How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing
    • Englander MT, Dulawa SC, Bhansali P, Schmauss C. How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing. J Neurosci 2005;25:648-651.
    • (2005) J Neurosci , vol.25 , pp. 648-651
    • Englander, M.T.1    Dulawa, S.C.2    Bhansali, P.3    Schmauss, C.4
  • 27
    • 25844472377 scopus 로고    scopus 로고
    • Estimating RNA editing efficiency of five editing sites in the serotonin 2C receptor by pyrosequencing
    • Iwamoto K, Bundo M, Kato T. Estimating RNA editing efficiency of five editing sites in the serotonin 2C receptor by pyrosequencing. Rna 2005;11:1596-1603.
    • (2005) Rna , vol.11 , pp. 1596-1603
    • Iwamoto, K.1    Bundo, M.2    Kato, T.3
  • 28
    • 0032752054 scopus 로고    scopus 로고
    • Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis
    • Takuma H, Kwak S, Yoshizawa T, Kanazawa I. Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis. Ann Neurol. 1999;46:806-815.
    • (1999) Ann Neurol , vol.46 , pp. 806-815
    • Takuma, H.1    Kwak, S.2    Yoshizawa, T.3    Kanazawa, I.4
  • 30
    • 66349122954 scopus 로고    scopus 로고
    • Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing
    • Li JB, Levanon EY, Yoon JK, Aach J, Xie B, Leproust E, et al. Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science. 2009;324:1210-1213.
    • (2009) Science , vol.324 , pp. 1210-1213
    • Li, J.B.1    Levanon, E.Y.2    Yoon, J.K.3    Aach, J.4    Xie, B.5    Leproust, E.6
  • 32
    • 0034535312 scopus 로고    scopus 로고
    • Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis
    • Wang Q, Khillan J, Gadue P, Nishikura K. Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis Science. 2000;290:1765-1768.
    • (2000) Science , vol.290 , pp. 1765-1768
    • Wang, Q.1    Khillan, J.2    Gadue, P.3    Nishikura, K.4
  • 33
    • 0029775644 scopus 로고    scopus 로고
    • RED2, a brain-specific member of the RNA-specific adenosine deaminase family
    • Melcher T, Maas S, Herb A, Sprengel R, Higuchi M, Seeburg PH. RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J Biol Chem. 1996;271:31795-31798.
    • (1996) J Biol Chem , vol.271 , pp. 31795-31798
    • Melcher, T.1    Maas, S.2    Herb, A.3    Sprengel, R.4    Higuchi, M.5    Seeburg, P.H.6
  • 34
    • 0034078399 scopus 로고    scopus 로고
    • A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single-and double-stranded RNA binding domains
    • Chen CX, Cho DS, Wang Q, Lai F, Carter KC, Nishikura K. A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single-and double-stranded RNA binding domains. RNA. 2000;6:755-767.
    • (2000) RNA , vol.6 , pp. 755-767
    • Chen, C.X.1    Cho, D.S.2    Wang, Q.3    Lai, F.4    Carter, K.C.5    Nishikura, K.6
  • 36
    • 57349192059 scopus 로고    scopus 로고
    • Newly identified ADARmediated A-to-I editing positions as a tool for ALS research
    • Kwak S, Nishimoto Y, Yamashita T. Newly identified ADARmediated A-to-I editing positions as a tool for ALS research. RNA Biol. 2008;5:193-197.
    • (2008) RNA Biol , vol.5 , pp. 193-197
    • Kwak, S.1    Nishimoto, Y.2    Yamashita, T.3
  • 38
    • 44149094073 scopus 로고    scopus 로고
    • Specificity of ADAR-mediated RNA editing in newly identified targets
    • Riedmann EM, Schopoff S, Hartner JC, Jantsch MF. Specificity of ADAR-mediated RNA editing in newly identified targets. RNA. 2008;14:1110-1118.
    • (2008) RNA , vol.14 , pp. 1110-1118
    • Riedmann, E.M.1    Schopoff, S.2    Hartner, J.C.3    Jantsch, M.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.