Search for transmembrane protein in gastric cancer by the Escherichia coli ampicillin secretion trap: Expression of DSC2 in gastric cancer with intestinal phenotype

Journal of Pathology

Volumn 221, Issue 3, 2010, Pages 275-284

  Anami, Katsuhiro ^a   Oue, Naohide ^a   Noguchi, Tsuyoshi ^b   Sakamoto, Naoya ^a   Sentani, Kazuhiro ^a   Hayashi, Tetsutaro ^a   Hinoi, Takao ^a   Okajima, Masazumi ^a   Graff, Jonathan M ^c   Yasui, Wataru ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b OITA UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

CAST; Desmocollin 2; DSC2; Gastric cancer

Indexed keywords

DESMOCOLLIN; DESMOCOLLIN 2; MEMBRANE PROTEIN; MUCIN; PROTEIN BST2; PROTEIN DRAM2; PROTEIN ZDHHC14; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

AGED; ARTICLE; CELL GROWTH; CELL INVASION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENE LIBRARY; GENE SEQUENCE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER;

AGED; CELL PROLIFERATION; DESMOCOLLINS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE LIBRARY; HOMEODOMAIN PROTEINS; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 77953516034     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2717     Document Type: Article

References (33)

1. Yasui W, Oue N, Kitadai Y, Nakayama H. Recent advances in molecular pathobiology of gastric carcinoma. In The Diversity of Gastric Carcinoma Pathogenesis: Diagnosis and Therapy, Kaminishi M, Takubo K, Mafune K (eds). Springer: Tokyo, 2005; 51-71.
2. Yasui W, Oue N, Ito R, Kuraoka K, Nakayama H. Search for new biomarkers of gastric cancer through serial analysis of gene expression and its clinical implications. Cancer Sci 2004; 95: 385-392.
3. Buckhaults P, Rago C, St Croix B, Romans KE, Saha S, Zhang L, et al. Secreted and cell surface genes expressed in benign and malignant colorectal tumors. Cancer Res 2001; 61: 6996-7001.
4. Oue N, Hamai Y, Mitani Y, Matsumura S, Oshimo Y, Aung PP, et al. Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression. Cancer Res 2004; 64: 2397-2405.
5. Aung PP, Oue N, Mitani Y, Nakayama H, Yoshida K, Noguchi T, et al. Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer. Oncogene 2006; 25: 2546-2557.
6. Mitani Y, Oue N, Matsumura S, Yoshida K, Noguchi T, Ito M, et al. Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy. Oncogene 2007; 26: 4383-4393.
7. Oue N, Sentani K, Noguchi T, Ohara S, Sakamoto N, Hayashi T, et al. Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients. Int J Cancer 2009; 125: 2383-2392.
8. Ferguson DA, Muenster MR, Zang Q, Spencer JA, Schageman JJ, Lian Y, et al. Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap. Cancer Res 2005; 65: 8209-8217.
9. von Heijne G. A new method for predicting signal sequence cleavage sites. Nucleic Acids Res 1986; 14: 4683-4690.
10. Kadonaga JT, Gautier AE, Straus DR, Charles AD, Edge MD, Knowles JR. The role of the beta-lactamase signal sequence in the secretion of proteins by Escherichia coli . J Biol Chem 1984; 259: 2149-2154.
11. Yin T, Green KJ. Regulation of desmosome assembly and adhesion. Semin Cell Dev Biol 2004; 15: 665-677.
12. Sentani K, Oue N, Noguchi T, Sakamoto N, Matsusaki K, Yasui W. Immunostaining of gastric cancer with neuroendocrine differentiation: Reg IV-positive neuroendocrine cells are associated with gastrin, serotonin, pancreatic polypeptide and somatostatin. Pathol Int (in press).
13. Sobin LH, Wittekind CH (eds). TNM Classification of Malignant Tumors (6th edn). Wiley-Liss: New York, 2002; 65-68.
14. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.
15. Kondo T, Oue N, Yoshida K, Mitani Y, Naka K, Nakayama H, et al. Expression of POT1 is associated with tumor stage and telomere length in gastric carcinoma. Cancer Res 2004; 64: 523-529. (Pubitemid 38120891)
16. Yasui W, Ayhan A, Kitadai Y, Nishimura K, Yokozaki H, Ito H, et al. Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas. Int J Cancer 1993; 53: 36-41. (Pubitemid 23018419)
17. Mizoshita T, Tsukamoto T, Nakanishi H, Inada K, Ogasawara N, Joh T, et al. Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol 2003; 129: 727-734. (Pubitemid 38002304)
18. Hinoi T, Lucas PC, Kuick R, Hanash S, Cho KR, Fearon ER. CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology 2002; 123: 1565-1577. (Pubitemid 35231656)
19. Alley MC, Scudiero DA, Monks A, Hursey ML, Czerwinski MJ, Fine DL, et al. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res 1988; 48: 589-601. (Pubitemid 18056527)
20. Khan K, Hardy R, Haq A, Ogunbiyi O, Morton D, Chidgey M. Desmocollin switching in colorectal cancer. Br J Cancer 2006; 95: 1367-1370.
21. Tatematsu M, Tsukamoto T, Inada K. Stem cells and gastric cancer: role of gastric and intestinal mixed intestinal metaplasia. Cancer Sci 2003; 94: 135-141. (Pubitemid 36575871)
22. Silberg DG, Sullivan J, Kang E, Swain GP, Moffett J, Sund NJ, et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology 2002; 122: 689-696. (Pubitemid 34173821)
23. Funakoshi S, Ezaki T, Kong J, Guo RJ, Lynch JP. Repression of the desmocollin 2 gene expression in human colon cancer cells is relieved by the homeodomain transcription factors Cdx1 and Cdx2. Mol Cancer Res 2008; 6: 1478-1490.
24. Hinoi T, Gesina G, Akyol A, Kuick R, Hanash S, Giordano TJ, et al. CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium. Gastroenterology 2005; 128: 946-961. (Pubitemid 40523546)
25. Tsukita S, Furuse M, Itoh M. Multifunctional strands in tight junctions. Nature Rev Mol Cell Biol 2001; 2: 285-293.
26. Sanada Y, Oue N, Mitani Y, Yoshida K, Nakayama H, Yasui W. Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype. J Pathol 2006; 208: 633-642.
27. Matsuda Y, Semba S, Ueda J, Fuku T, Hasuo T, Chiba H, et al. Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. Cancer Sci 2007; 98: 1014-1019. (Pubitemid 46865385)
28. Berndorff D, Gessner R, Kreft B, Schnoy N, Lajous-Petter AM, Loch N, et al. Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine. J Cell Biol 1994; 125: 1353-1369.
29. Motoshita J, Nakayama H, Taniyama K, Matsusaki K, Yasui W. Molecular characteristics of differentiated-type gastric carcinoma with distinct mucin phenotype: LI-cadherin is associated with intestinal phenotype. Pathol Int 2006; 56: 200-205.
30. Tajima Y, Shimoda T, Nakanishi Y, Yokoyama N, Tanaka T, Shimizu K, et al. Association of gastric and intestinal phenotypic marker expression of gastric carcinomas with tumor thymidylate synthase expression and response to postoperative chemotherapy with 5-fluorouracil. J Cancer Res Clin Oncol 2003; 129: 683-690. (Pubitemid 38002299)
31. Ochiai A, Yasui W, Tahara E. Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1. Jpn J Cancer Res 1985; 76: 1064-1071. (Pubitemid 16175800)
32. Yanagihara K, Seyama T, Tsumuraya M, Kamada N, Yokoro K. Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene. Cancer Res 1991; 51: 381-386.
33. Sakamoto N, Oue N, Noguchi T, Sentani K, Anami K, Sanada Y, et al. Serial analysis of gene expression of esophageal squamous cell carcinoma: ADAMTS16 is up-regulated in esophageal squamous cell carcinoma. Cancer Sci (in press).