Oxidative stress-induced homologous recombination as a novel mechanism for phenytoin-initiated toxicity

Journal of Pharmacology and Experimental Therapeutics

Volumn 306, Issue 2, 2003, Pages 523-527

  Winn, Louise M ^a   Kim, Perry M ^a   Nickoloff, Jac A ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DOUBLE STRANDED DNA; GENE PRODUCT; PHENYTOIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DNA STRUCTURE; DRUG ACTIVATION; GENE CONVERSION; GENETIC DAMAGE; HOMOLOGOUS RECOMBINATION; HYPOTHESIS; MACROMOLECULE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; TERATOGENESIS; TIME;

ANIMALS; CHO CELLS; CRICETINAE; DNA; DNA DAMAGE; DRUG TOXICITY; FEMALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENYTOIN; RECOMBINATION, GENETIC;

EID: 0038298234     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.052639     Document Type: Article

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