|
Volumn 343, Issue 6, 2010, Pages 360-366
|
Design and synthesis of novel pyrazino[2,1-a]isoquinoline derivatives with potent antifungal activity
|
Author keywords
Antifungal; Lanosterol 14 demethylase; Pyrazino 2,1 a isoquinoline; Synthesis
|
Indexed keywords
2 DECYL 2,3,6,7 TETRAHYDRO 10 FLUORO 1H PYRAZINO[2,1 A]ISOQUINOLIN 4(11BH) ONE;
ANTIFUNGAL AGENT;
FLUCONAZOLE;
LANOSTEROL;
PYRAZINO[2,1 A]ISOQUINOLINE;
STEROL 14ALPHA DEMETHYLASE;
UNCLASSIFIED DRUG;
VORICONAZOLE;
ANTIFUNGAL ACTIVITY;
ARTICLE;
BINDING AFFINITY;
DRUG BINDING SITE;
DRUG DESIGN;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
FUNGAL STRAIN;
IN VITRO STUDY;
INFRARED SPECTROMETRY;
LIGAND BINDING;
MASS SPECTROMETRY;
NONHUMAN;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
ANTIFUNGAL AGENTS;
CANDIDA;
CRYPTOCOCCUS NEOFORMANS;
CYTOCHROME P-450 ENZYME SYSTEM;
DRUG DESIGN;
FUNGI;
ISOQUINOLINES;
MICROBIAL SENSITIVITY TESTS;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
PYRAZINES;
TRICHOPHYTON;
|
EID: 77953497970
PISSN: 03656233
EISSN: 15214184
Source Type: Journal
DOI: 10.1002/ardp.200900279 Document Type: Article |
Times cited : (7)
|
References (17)
|