Fuzi polysaccharide-1 produces antidepressant-like effects in mice

International Journal of Neuropsychopharmacology

Volumn 13, Issue 5, 2010, Pages 623-633

  Yan, Hua Cheng ^a   Qu, Hong Da ^a,b   Sun, Li Rong ^a   Li, Shu Ji ^a   Cao, Xiong ^a   Fang, Ying Ying ^a   Jie, Wei ^a   Bean, Jonathan C ^c   Wu, Wei Kang ^b   Zhu, Xin Hong ^a   Gao, Tian Ming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Adult neurogenesis; Antidepressant; Depression; Fuzi polysaccharide 1

Indexed keywords

ACONITUM EXTRACT; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN MONOAMINE; BROXURIDINE; FUZI POLYSACCHARIDE 1; IMIPRAMINE; K 252A; UNCLASSIFIED DRUG;

ACONITE; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVOIDANCE BEHAVIOR; CELL PROLIFERATION; CHINESE MEDICINE; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SOCIAL STRESS; STRESS; WESTERN BLOTTING;

ACONITUM; ANIMALS; ANTIDEPRESSIVE AGENTS; DENTATE GYRUS; DEPRESSION; GLUCANS; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; PLANT ROOTS; POLYSACCHARIDES; RANDOM ALLOCATION;

EID: 77953486945     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145709990733     Document Type: Article

References (41)

1. Airan RD, Meltzer LA, Roy M, Gong Y, et al. (2007). High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science 317, 819-823.
2. Alonso R, Griebel G, Pavone G, Stemmelin J, et al. (2004). Blockade of CRF1 or V-1b receptors reverses stress induced suppression of neurogenesis in a mouse model of depression. Molecular Psychiatry 9, 278-286. (Pubitemid 38496719)
3. Berton O, McClung CA, Dileone RJ, Krishnan V, et al. (2006). Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311, 864-868.
4. Cameron HA, McKay RD (2001). Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. Journal of Comparative Neurology 435, 406-417.
5. Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT (2001). Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biological Psychiatry 50, 260-265.
6. Chen ZY, Jing D, Bath KG, Ieraci A, et al. (2006). Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314, 140-143.
7. Cryan JF, Markou A, Lucki I (2002). Assessing antidepressant activity in rodents: recent developments and future needs. Trends in Pharmacological Sciences 23, 238-245.
8. Czeh B, Michaelis T, Watanabe T, Frahm J, et al. (2001). Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proceedings of the National Academy Sciences USA 98, 12796-12801.
9. Dulawa SC, Hen R (2005). Recent advances in animal models of chronic antidepressant effects: The novelty-induced hypophagia test. Neuroscience and Biobehavioral Reviews 29, 771-783.
10. Dulawa SC, Holick KA, Gundersen B, Hen R (2004). Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology 29, 1321-1330.
11. Elhwuegi AS (2004). Central monoamines and their role in major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry 28, 435-451.
12. Hikino H, Mizuno T, Oshima Y, Konno C (1985). Isolation and hypoglycemic activity of aconitans A, B, C and D, glycans of Aconitum carmichaeli Roots. Planta Medica 51, 160-161.
13. Jiang W, Zhang Y, Xiao L, Van Cleemput J, et al. (2005). Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic-and antidepressant-like effects. Journal of Clinical Investigation 115, 3104-3116.
14. Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH (2003). Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130, 391-399.
15. Krishnan V, Han MH, Graham DL, Berton O, et al. (2007). Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131, 391-404.
16. Leveugle B, Ding W, Laurence F, Dehouck MP, et al. (1998). Heparin oligosaccharides that pass the blood-brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide. Journal of Neurochemistry 70, 736-744.
17. Ma Q, Dudas B, Hejna M, Cornelli U, et al. (2002). The blood-brain barrier accessibility of a heparin-derived oligosaccharides C3. Thrombosis Research 105, 447-453.
18. Malberg JE, Duman RS (2003). Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology 28, 1562-1571.
19. Malberg JE, Eisch AJ, Nestler EJ, Duman RS (2000). Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. Journal of Neuroscience 20, 9104-9110.
20. Malberg JE, Schechter LE (2005). Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs. Current Pharmaceutical Design 11, 145-155.
21. Monteggia LM, Luikart B, Barrot M, Theobold D, et al. (2007). Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry 61, 187-197.
22. Mullen RJ, Buck CR, Smith AM (1992). NeuN, a neuronal specific nuclear protein in vertebrates. Development 116, 201-211.
23. Nemeroff C, Owens M (2002). Treatment of mood disorders. Nature Neuroscience 5, 1068-1070.
24. Nestler E, Barrot M, DiLeone R, Eisch A, et al. (2002). Neurobiology of depression. Neuron 34, 13-25.
25. Newton SS, Duman RS (2004). Regulation of neurogenesis and angiogenesis in depression. Current Neurovascular Research 1, 261-267.
26. Ngwenya LB, Peters A, Rosene DL (2006). Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey. Journal of Comparative Neurology 498, 204-216.
27. Nibuya M, Morinobu S, Duman RS (1995). Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. Journal of Neuroscience 15, 7539-7547.
28. Porsolt RD, Bretin A, Jalfre M (1977). Behavioral despair in mice: a primary screening test for antidepressants. Achieves International Pharmacodynamic Therapy 229, 327-336.
29. Sahay A, Hen R (2007). Adult hippocampal neurogenesis in depression. Nature Neuroscience 10, 1110-1115.
30. Santarelli L, Saxe M, Gross C, Surget A, et al. (2003). Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809.
31. Schloss P, Henm FA (2004). New insights into the mechanisms of antidepressant therapy. Pharmacology & Therapeutics 102, 47-60.
32. Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS (2002). Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. Journal of Neuroscience 22, 3251-3261.
33. Smith MA, Makino S, Kvetnansky R, Post RM (1995). Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. Journal of Neuroscience 15, 1768-1777.
34. Taki M, Niitu K, Omiya Y, Noguchi M, et al. (2003). 8-O-cinnamoylneoline, a new alkaloid from the flower buds of Aconitum carmichaeli and its toxic and analgesic activities. Planta Medica 69, 800-803.
35. Tashiro A, Makino H, Gage FH (2007). Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. Journal of Neuroscience 27, 3252-3259.
36. Trivedi MH (2003). Treatment-resistant depression: new therapies on the horizon. Annals of Clinical Psychiatry 15, 59-70.
37. Tsankova NM, Berton O, Renthal W, Kumar A, et al. (2006). Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nature Neuroscience 9, 519-525.
38. Wesolowska A, Kowalska M (2008). Influence of serotonin 5-HT7 receptor blockade on the behavioral and neurochemical effects of imipramine in rats. Pharmacological Reports 60, 464-474.
39. Yap JJ, Takase LF, Kochman LJ, Fornal CA, et al. (2006). Repeated brief social defeat episodes in mice: effect on cell proliferation in the dentate gyrus. Behavioural Brain Research 172, 344-350.
40. Zhang H (2006). The clinical and theory study of rouse yang-qi method on depression. Journal of Shangdong University of Traditional Chinese Medicine 30, 140-143.
41. Zhao C, Li M, Luo YF, Wu WK (2006). Isolation and structural characterization of an immunostimulating polysaccharide from fuzi Aconitum carmichaeli. Carbohydrate Research 341, 485-491.