Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts

Human Genetics

Volumn 127, Issue 6, 2010, Pages 639-649

  Nielsen, David A ^a,b,c   Hamon, Sara ^a   Yuferov, Vadim ^a   Jackson, Colin ^a   Ho, Ann ^a   Ott, Jurg ^d   Kreek, Mary Jeanne ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Chinese Academy of Sciences and China National Center for Bioinformation   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; DIAMORPHINE; DNA; METHADONE; OPIATE RECEPTOR; CYTIDYLYL 3' 5' GUANOSINE; CYTIDYLYL-3'-5'-GUANOSINE; DINUCLEOSIDE PHOSPHATE; MU OPIATE RECEPTOR; OPRM1 PROTEIN, HUMAN;

ADULT; AFRICAN AMERICAN; ARTICLE; CAUCASIAN; COHORT ANALYSIS; CONTROLLED STUDY; DNA DETERMINATION; DNA METHYLATION; ETHNICITY; FEMALE; HEROIN DEPENDENCE; HISPANIC; HUMAN; LYMPHOCYTE; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; METHADONE TREATMENT; PRIORITY JOURNAL; PROMOTER REGION; RACE DIFFERENCE; RECEPTOR GENE; ETHNIC GROUP; GENETICS; LYMPHOCYTE COUNT; METABOLISM;

AFRICAN AMERICANS; DINUCLEOSIDE PHOSPHATES; DNA METHYLATION; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; HEROIN DEPENDENCE; HISPANIC AMERICANS; HUMANS; LYMPHOCYTE COUNT; LYMPHOCYTES; RECEPTORS, OPIOID, MU;

EID: 77953474087     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-010-0807-6     Document Type: Article

References (52)

1. Alikhani-Koopaei R, Fouladkou F, Frey FJ, Frey BM (2004) Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. J Clin Invest 114:1146-1157
2. Ballestar E, Wolffe AP (2001) Methyl-CpG-binding proteins. Targeting specific gene repression. Eur J Biochem 268:1-6
3. Bleich S, Lenz B, Ziegenbein M, Beutler S, Frieling H, Kornhuber J, Bonsch D (2006) Epigenetic DNA hypermethylation of the HERP gene promoter induces down-regulation of its mRNA expression in patients with alcohol dependence. Alcohol Clin Exp Res 30:587-591
4. Bonsch D, Lenz B, Reulbach U, Kornhuber J, Bleich S (2004) Homocysteine associated genomic DNA hypermethylation in patients with chronic alcoholism. J Neural Transm 111:1611-1616
5. Bonsch D, Lenz B, Kornhuber J, Bleich S (2005) DNA hypermethy-lation of the alpha synuclein promoter in patients with alcoholism. Neuroreport 16:167-170
6. Bonsch D, Lenz B, Fiszer R, Frieling H, Kornhuber J, Bleich S (2006) Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism. J Neural Transm 113:1299-1304
7. Cheng CK, Chow LW, Loo WT, Chan TK, Chan V (2005) The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer. Cancer Res 65:8646-8654
8. Choy JS, Wei S, Lee JY, Tan S, Chu S, Lee TH (2010) DNA methylation increases nucleosome compaction and rigidity. J Am Chem Soc 132:1782-1783
9. Das PM, Ramachandran K, Vanwert J, Ferdinand L, Gopisetty G, Reis IM, Singal R (2006) Methylation mediated silencing of TMS1/ASC gene in prostate cancer. Mol Cancer 5:28
10. Douet V, Heller MB, Le Saux O (2007) DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoter. Biochem Biophys Res Commun 354:66-71
11. Durcova-Hills G, Burgoyne P, McLaren A (2004) Analysis of sex differences in EGC imprinting. Dev Biol 268:105-110
12. Durcova-Hills G, Hajkova P, Sullivan S, Barton S, Surani MA, McLaren A (2006) Influence of sex chromosome constitution on the genomic imprinting of germ cells. Proc Natl Acad Sci USA 103:11184-11188
13. El-Maarri O, Becker T, Junen J, Manzoor SS, Diaz-Lacava A, Schwaab R, Wienker T, Oldenburg J (2007) Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males. Hum Genet 122:505-514
14. Enoch MA, Shen PH, Xu K, Hodgkinson C, Goldman D (2006) Using ancestry-informative markers to define populations and detect population stratification. J Psychopharmacol 20:19-26
15. Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, Heine-Suner D, Cigudosa JC, Urioste M, Benitez J, Boix-Chornet M, Sanchez-Aguilera A, Ling C, Carlsson E, Poulsen P, Vaag A, Stephan Z, Spector TD, Wu YZ, Plass C, Esteller M (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 102:10604-10609
16. Franchina M, Kay PH (2001) Novel nucleotide substitutions within the coding region of DNMT2 are in strong linkage disequilibrium in Caucasians and Japanese. Hum Hered 52:210-216
17. Halekoh U, Hojsgaard S (2006) The R package geepack for generalized estimating equations. J Stat Softw 15:1-11
18. Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE, Lumey LH (2008) Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 105:17046-17049
19. Heller G, Schmidt WM, Ziegler B, Holzer S, Mullauer L, Bilban M, Zielinski CC, Drach J, Zochbauer-Muller S (2008) Genome-wide transcriptional response to 5-aza-2-deoxycytidine and trichostatin a in multiple myeloma cells. Cancer Res 68:44-54
20. Hillemacher T, Frieling H, Luber K, Yazici A, Muschler MA, Lenz B, Wilhelm J, Kornhuber J, Bleich S (2009) Epigenetic regulation and gene expression of vasopressin and atrial natriuretic peptide in alcohol withdrawal. Psychoneuroendocrinology 34:555-560
21. Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH (2007) Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol 27:4720-4736
22. Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH (2008) Epigenetic programming of mu opioid receptor gene in mouse brain is regulated by MeCP2 and brg1 chromatin remodelling factor. J Cell Mol Med 13:3591-3615
23. Iguchi-Ariga SM, Schaffner W (1989) CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev 3:612-619
24. Jane SM, Gumucio DL, Ney PA, Cunningham JM, Nienhuis AW (1993) Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression. Mol Cell Biol 13:3272-3281
25. Kreek MJ, Bart G, Lilly C, LaForge KS, Nielsen DA (2005) Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol Rev 57:1-26
26. Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ (2005) Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48:303-314
27. Lao O, van Duijn K, Kersbergen P, de Knijff P, Kayser M (2006) Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry. Am J Hum Genet 78:680-690
28. Levran O, Londono D, O'Hara K, Nielsen DA, Peles E, Rotrosen J, Casadonte P, Linzy S, Randesi M, Ott J, Adelson M, Kreek MJ (2008) Genetic susceptibility to heroin addiction: a candidate gene association study. Genes Brain Behav 7:720-729
29. Levran O, Londono D, O'Hara K, Randesi M, Rotrosen J, Casadonte P, Linzy S, Ott J, Adelson M, Kreek MJ (2009) Heroin addiction in African Americans: a hypothesis-driven association study. Genes Brain Behav 8:531-540
30. Lewin J, Schmitt AO, Adorjan P, Hildmann T, Piepenbrock C (2004) Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics 20:3005-3012
31. Liu X-Q, Paterson AD, John EM, Knight JA (2006) The role of self-defined race/ethnicity in population structure control. Ann Human Genet 70:496-505
32. Maksakova IA, Mager DL, Reiss D (2008) Keeping active endogenous retroviral-like elements in check: the epigenetic perspective. Cell Mol Life Sci 65:3329-3347
33. McLellan AT, Luborsky L, Woody GE, O'Brien CP (1980) An improved diagnostic evaluation instrument for substance abuse patients: the addiction severity index. J Nerv Ment Dis 168:26-33
34. Michelotti GA, Brinkley DM, Morris DP, Smith MP, Louie RJ, Schwinn DA (2007) Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. FASEB J 21:1979-1993
35. Miller CA, Sweatt JD (2007) Covalent modification of DNA regulates memory formation. Neuron 53:857-869
36. Nielsen DA, Ji F, Yuferov V, Ho A, Chen A, Levran O, Ott J, Kreek MJ (2008) Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Mol Psychiatry 13:417-428
37. Nielsen DA, Yuferov V, Hamon S, Jackson C, Ho A, Ott J, Kreek MJ (2009) Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts. Neuropsychophar-macology 34:867-873
38. Novikova SI, He F, Bai J, Cutrufello NJ, Lidow MS, Undieh AS (2008) Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring. PLoS One 3:e1919
39. Philibert RA, Gunter TD, Beach SR, Brody GH, Madan A (2008) MAOA methylation is associated with nicotine and alcohol dependence in women. Am J Med Genet B Neuropsychiatr Genet 147B:565-570
40. Renthal W, Maze I, Krishnan V, Covington HE 3rd, Xiao G, Kumar A, Russo SJ, Graham A, Tsankova N, Kippin TE, Kerstetter KA, Neve RL, Haggarty SJ, McKinsey TA, Bassel-Duby R, Olson EN, Nestler EJ (2007) Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 56:517-529
41. Renthal W, Carle TL, Maze I, Covington HE 3rd, Truong HT, Alibhai I, Kumar A, Montgomery RL, Olson EN, Nestler EJ (2008) Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. J Neurosci 28:7344-7349
42. Rettig RA, Yarmolinsky A (1995) Federal regulation of methadone treatment. National Academy Press, Washington, DC
43. Ronn T, Poulsen P, Hansson O, Holmkvist J, Almgren P, Nilsson P, Tuomi T, Isomaa B, Groop L, Vaag A, Ling C (2008) Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle. Diabetologia 51:1159-1168
44. Sarter B, Long TI, Tsong WH, Koh WP, Yu MC, Laird PW (2005) Sex differential in methylation patterns of selected genes in Singapore Chinese. Hum Genet 117:402-403
45. Schug J, Overton GC (1977) TESS: transcription element search software on the www. computational biology and informatics laboratory. School of Medicine, University of Pennsylvania, Philadelphia, PA
46. Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A, Pankow JS, Province MA, Hunt SC, Boerwinkle E, Schork NJ, Risch NJ (2005) Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet 76:268-275
47. Tate PH, Bird AP (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 3:226-231
48. Terry MB, Ferris JS, Pilsner R, Flom JD, Tehranifar P, Santella RM, Gamble MV, Susser E (2008) Genomic DNA methylation among women in a multiethnic New York City birth cohort. Cancer Epidemiol Biomarkers Prev 17:2306-2310
49. Tomii K, Tsukuda K, Toyooka S, Kote H, JHanafusa T, Asano H, Naitou M, Doihara H, Kisimoto T, Katayama H, Pass HI, Kate H, Shimizu N (2006) Aberant promoter methylation of insulinlike growth factor binding protein-3 gene in human cancers. Int J Cancer 120:566-573
50. Zhang H, Darwanto A, Linkhart TA, Sowers LC, Zhang L (2007) Maternal cocaine administration causes an epigenetic modification of protein kinase C epsilon gene expression in fetal rat heart. Mol Pharmacol 71:1319-1328
51. Zhang X, Wu M, Xiao H, Lee MT, Levin L, Leung YK, Ho SM (2010) Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer. Prostate [Epub ahead of print]
52. Zhao H, Du W, Gu D, Wang D, Xue F, Ge J, Sui T, Yang R (2009) DNMT3B 579G[T promoter polymorphism and the risk for idiopathic thrombocytopenic purpura in a Chinese population. Acta Haematol 122:31-35