메뉴 건너뛰기




Volumn 2, Issue 7, 2008, Pages 801-811

Biomarkers for malignant peripheral nerve sheath tumours

Author keywords

Biomarkers; Differential diagnosis; Malignant peripheral nerve sheath tumour; Neurofibroma

Indexed keywords

CD57 ANTIGEN; COLLAGENASE 3; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; KI 67 ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; MATRIX METALLOPROTEINASE 14; MYELIN BASIC PROTEIN; NESTIN; NEUROFIBROMIN; ONCOLYTIC HERPES VIRUS; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P16; PROTEIN P27; PROTEIN P53; PROTEIN S 100; RAS PROTEIN; RETINOBLASTOMA PROTEIN; STEROID HORMONE; SURVIVIN; TENASCIN; TUMOR MARKER;

EID: 77953462959     PISSN: 17530059     EISSN: 17530067     Source Type: Journal    
DOI: 10.1517/17530059.2.7.801     Document Type: Review
Times cited : (3)

References (86)
  • 1
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114(2):97-109
    • (2007) Acta Neuropathol , vol.114 , Issue.2 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 2
    • 0035873187 scopus 로고    scopus 로고
    • Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: A study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group
    • Coindre JM, Terrier P, Guillou L, et al. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group. Cancer 2001;91(10):1914-26
    • (2001) Cancer , vol.91 , Issue.10 , pp. 1914-1926
    • Coindre, J.M.1    Terrier, P.2    Guillou, L.3
  • 3
    • 0026471917 scopus 로고
    • Prognostic significance of histologic parameters of soft tissue sarcomas
    • Hashimoto H, Daimaru Y, Takeshita S, et al. Prognostic significance of histologic parameters of soft tissue sarcomas. Cancer 1992;70(12):2816-22
    • (1992) Cancer , vol.70 , Issue.12 , pp. 2816-2822
    • Hashimoto, H.1    Daimaru, Y.2    Takeshita, S.3
  • 4
    • 0022924141 scopus 로고
    • Neurofibromatosis and cancer
    • Bader JL. Neurofibromatosis and cancer. Ann NY Acad Sci 1986;486:57-65
    • (1986) Ann NY Acad Sci , vol.486 , pp. 57-65
    • Bader, J.L.1
  • 6
    • 33947236808 scopus 로고    scopus 로고
    • Histopathology and clinical outcome of NF1-associated vs. sporadic malignant peripheral nerve sheath tumors
    • Hagel C, Zils U, Peiper M, et al. Histopathology and clinical outcome of NF1-associated vs. sporadic malignant peripheral nerve sheath tumors. J Neuro Oncol 2007;82(2):187-92
    • (2007) J Neuro Oncol , vol.82 , Issue.2 , pp. 187-192
    • Hagel, C.1    Zils, U.2    Peiper, M.3
  • 7
    • 77953398593 scopus 로고    scopus 로고
    • Weiss SW, Goldblum JR, Enzinger FM. Enzinger and Weiss's soft tissue tumors. Edition. Mosby, St Louis; 2001. p. xiv, 1622
    • Weiss SW, Goldblum JR, Enzinger FM. Enzinger and Weiss's soft tissue tumors. Edition. Mosby, St Louis; 2001. p. xiv, 1622
  • 8
    • 0026501509 scopus 로고
    • Peripheral nerve sheath differentiation in malignant soft tissue tumours: An ultrastructural and immunohistochemical study
    • Fisher C, Carter RL, Ramachandra S, Thomas DM. Peripheral nerve sheath differentiation in malignant soft tissue tumours: an ultrastructural and immunohistochemical study. Histopathology 1992;20(2):115-25
    • (1992) Histopathology , vol.20 , Issue.2 , pp. 115-125
    • Fisher, C.1    Carter, R.L.2    Ramachandra, S.3    Thomas, D.M.4
  • 9
    • 0029060246 scopus 로고
    • Cytogenetic findings in malignant peripheral nerve sheath tumors
    • Mertens F, Rydholm A, Bauer HF, et al. Cytogenetic findings in malignant peripheral nerve sheath tumors. Int J Cancer 1995;61(6):793-8
    • (1995) Int J Cancer , vol.61 , Issue.6 , pp. 793-798
    • Mertens, F.1    Rydholm, A.2    Bauer, H.F.3
  • 10
    • 0343851081 scopus 로고    scopus 로고
    • Cytogenetic characterization of peripheral nerve sheath tumours: A report of the CHAMP study group
    • Mertens F, Dal Cin P, De Wever I, et al. Cytogenetic characterization of peripheral nerve sheath tumours: a report of the CHAMP study group. J Pathol 2000;190(1):31-8
    • (2000) J Pathol , vol.190 , Issue.1 , pp. 31-38
    • Mertens, F.1    Dal Cin, P.2    De Wever, I.3
  • 11
    • 0028631156 scopus 로고
    • Cytogenetic analysis of soft tissue sarcomas. Recurrent chromosome abnormalities in malignant peripheral nerve sheath tumors (MPNST)
    • Jhanwar SC, Chen Q, Li FP, et al. Cytogenetic analysis of soft tissue sarcomas. Recurrent chromosome abnormalities in malignant peripheral nerve sheath tumors (MPNST). Cancer Genet Cytogenet 1994;78(2):138-44
    • (1994) Cancer Genet Cytogenet , vol.78 , Issue.2 , pp. 138-144
    • Jhanwar, S.C.1    Chen, Q.2    Li, F.P.3
  • 12
    • 33644768087 scopus 로고    scopus 로고
    • Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: A study of 10 tumors from nine patients
    • Kobayashi C, Oda Y, Takahira T, et al. Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: a study of 10 tumors from nine patients. Cancer Genet Cytogenet 2006;165(2):98-105
    • (2006) Cancer Genet Cytogenet , vol.165 , Issue.2 , pp. 98-105
    • Kobayashi, C.1    Oda, Y.2    Takahira, T.3
  • 13
    • 2442715146 scopus 로고    scopus 로고
    • Comparative genomic hybridization in central and peripheral nervous system tumors of childhood and adolescence
    • Rickert CH, Paulus W. Comparative genomic hybridization in central and peripheral nervous system tumors of childhood and adolescence. J Neuropathol Exp Neurol 2004;63(5):399-417
    • (2004) J Neuropathol Exp Neurol , vol.63 , Issue.5 , pp. 399-417
    • Rickert, C.H.1    Paulus, W.2
  • 14
    • 0027468594 scopus 로고
    • Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis
    • Legius E, Marchuk DA, Collins FS, Glover TW. Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis. Nat Genet 1993;3(2):122-6
    • (1993) Nat Genet , vol.3 , Issue.2 , pp. 122-126
    • Legius, E.1    Marchuk, D.A.2    Collins, F.S.3    Glover, T.W.4
  • 15
    • 10744220011 scopus 로고    scopus 로고
    • Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors
    • Upadhyaya M, Han S, Consoli C, et al. Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors. Hum Mutat 2004;23(2):134-46
    • (2004) Hum Mutat , vol.23 , Issue.2 , pp. 134-146
    • Upadhyaya, M.1    Han, S.2    Consoli, C.3
  • 16
    • 0035405619 scopus 로고    scopus 로고
    • NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors
    • Perry A, Roth KA, Banerjee R, et al. NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors. Am J Pathol 2001;159(1):57-61
    • (2001) Am J Pathol , vol.159 , Issue.1 , pp. 57-61
    • Perry, A.1    Roth, K.A.2    Banerjee, R.3
  • 17
    • 0025201012 scopus 로고
    • The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
    • Ballester R, Marchuk D, Boguski M, et al. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 1990;63(4):851-9
    • (1990) Cell , vol.63 , Issue.4 , pp. 851-859
    • Ballester, R.1    Marchuk, D.2    Boguski, M.3
  • 18
    • 0027732538 scopus 로고    scopus 로고
    • Boguski MS, McCormick F. Proteins regulating Ras and its relatives. Nature 193;366(6456):643-54
    • Boguski MS, McCormick F. Proteins regulating Ras and its relatives. Nature 193;366(6456):643-54
  • 19
    • 33749009578 scopus 로고    scopus 로고
    • Maertens O, Brems H, Vandesompele J, et al. Comprehensive NF1 screening on cultured Schwann cells from neurofibromas. Hum Mutat 206;27(10):1030-40
    • Maertens O, Brems H, Vandesompele J, et al. Comprehensive NF1 screening on cultured Schwann cells from neurofibromas. Hum Mutat 206;27(10):1030-40
  • 20
    • 0034642298 scopus 로고    scopus 로고
    • Schwann cells harbor the somatic NF1 mutation in neurofibromas: Evidence of two different Schwann cell subpopulations
    • Serra E, Rosenbaum T, Winner U, et al. Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations. Hum Mol Genet 2000;9(20):3055-64
    • (2000) Hum Mol Genet , vol.9 , Issue.20 , pp. 3055-3064
    • Serra, E.1    Rosenbaum, T.2    Winner, U.3
  • 21
    • 0035007009 scopus 로고    scopus 로고
    • Somatic NF1 mutational spectrum in benign neurofibromas: MRNA splice defects are common among point mutations
    • Serra E, Ars E, Ravella A, et al. Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations. Hum Genet 2001;108(5):416-29
    • (2001) Hum Genet , vol.108 , Issue.5 , pp. 416-429
    • Serra, E.1    Ars, E.2    Ravella, A.3
  • 22
    • 0032914916 scopus 로고    scopus 로고
    • Loss of NF1 allele in Schwann cells but not in fibroblasts derived from an NF1-associated neurofibroma
    • Kluwe L, Friedrich R, Maumer VF. Loss of NF1 allele in Schwann cells but not in fibroblasts derived from an NF1-associated neurofibroma. Genes Chromosomes Cancer 1999;24(3):283-5
    • (1999) Genes Chromosomes Cancer , vol.24 , Issue.3 , pp. 283-285
    • Kluwe, L.1    Friedrich, R.2    Maumer, V.F.3
  • 23
    • 0034639937 scopus 로고    scopus 로고
    • Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1
    • Rutkowski JL, Wu K, Gutmann DH, et al. Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1. Hum Mol Genet 2000;9(7):1059-66
    • (2000) Hum Mol Genet , vol.9 , Issue.7 , pp. 1059-1066
    • Rutkowski, J.L.1    Wu, K.2    Gutmann, D.H.3
  • 24
    • 0034730635 scopus 로고    scopus 로고
    • Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts
    • Sherman LS, Atit R, Rosenbaum T, et al. Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem 2000;275(39):30740-5
    • (2000) J Biol Chem , vol.275 , Issue.39 , pp. 30740-30745
    • Sherman, L.S.1    Atit, R.2    Rosenbaum, T.3
  • 25
    • 0028146806 scopus 로고
    • TP53 mutations are frequent in malignant NF1 tumors
    • Legius E, Dierick H, Wu R, et al. TP53 mutations are frequent in malignant NF1 tumors. Genes Chromosomes Cancer 1994;10(4):250-5
    • (1994) Genes Chromosomes Cancer , vol.10 , Issue.4 , pp. 250-255
    • Legius, E.1    Dierick, H.2    Wu, R.3
  • 26
    • 0025108408 scopus 로고
    • Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis
    • Menon AG, Anderson KM, Riccardi VM, et al. Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis. Proc Natl Acad Sci USA 1990;87(14):5435-9
    • (1990) Proc Natl Acad Sci USA , vol.87 , Issue.14 , pp. 5435-5439
    • Menon, A.G.1    Anderson, K.M.2    Riccardi, V.M.3
  • 27
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev 2002;2(8):594-604
    • (2002) Nat Rev , vol.2 , Issue.8 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 28
    • 0034671945 scopus 로고    scopus 로고
    • Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
    • Sigal A, Rotter V. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 2000;60(24):6788-93
    • (2000) Cancer Res , vol.60 , Issue.24 , pp. 6788-6793
    • Sigal, A.1    Rotter, V.2
  • 29
    • 3843053704 scopus 로고    scopus 로고
    • p15INK4b, p 14ARF, and p16INK4a inactivation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
    • Petrone F, Tabano S, Colombo F, et al. p15INK4b, p 14ARF, and p16INK4a inactivation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors. Clin Cancer Res 2003;9(11):4132-8
    • (2003) Clin Cancer Res , vol.9 , Issue.11 , pp. 4132-4138
    • Petrone, F.1    Tabano, S.2    Colombo, F.3
  • 30
    • 0032763415 scopus 로고    scopus 로고
    • Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas
    • Kourea HP, Orlow I, Scheithauer BW, et al. Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas. Am J Pathol 1999;155(6):1855-60
    • (1999) Am J Pathol , vol.155 , Issue.6 , pp. 1855-1860
    • Kourea, H.P.1    Orlow, I.2    Scheithauer, B.W.3
  • 31
    • 0032762784 scopus 로고    scopus 로고
    • Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inacuvation
    • Nielsen GP, Stemmer-Rachamimov AO, Ino Y, et al. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inacuvation. Am J Pathol 1999;155(6):1879-84
    • (1999) Am J Pathol , vol.155 , Issue.6 , pp. 1879-1884
    • Nielsen, G.P.1    Stemmer-Rachamimov, A.O.2    Ino, Y.3
  • 32
    • 0036320356 scopus 로고    scopus 로고
    • Mawrin C, Kirches E, Boltze C, et al. Immunohistochemical and molecular analysis of p53, RB, and PTEN in malignant peripheral nerve sheath tumors. Virchows Arch 2002;440(6):610-5
    • Mawrin C, Kirches E, Boltze C, et al. Immunohistochemical and molecular analysis of p53, RB, and PTEN in malignant peripheral nerve sheath tumors. Virchows Arch 2002;440(6):610-5
  • 33
    • 0034102193 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models
    • Declue JE, Heffelfinger S, Benvenuto G, et al. Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models. J Clin Invest 2000;105(9):1233-41
    • (2000) J Clin Invest , vol.105 , Issue.9 , pp. 1233-1241
    • Declue, J.E.1    Heffelfinger, S.2    Benvenuto, G.3
  • 34
    • 33644862170 scopus 로고    scopus 로고
    • Mutation and expression of PDGFRA and KIT in malignant peripheral nerve sheath tumors, and its implications for imatinib sensitivity
    • Holtkamp N, Okuducu AF, Mucha J, et al. Mutation and expression of PDGFRA and KIT in malignant peripheral nerve sheath tumors, and its implications for imatinib sensitivity. Carcinogenesis 2006;27(3):664-71
    • (2006) Carcinogenesis , vol.27 , Issue.3 , pp. 664-671
    • Holtkamp, N.1    Okuducu, A.F.2    Mucha, J.3
  • 35
    • 0029795740 scopus 로고    scopus 로고
    • Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghansen's neurofibromatosis
    • Lothe RA, Karhu R, Mandahl N, et al. Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghansen's neurofibromatosis. Cancer Res 1996;56(20):4778-81
    • (1996) Cancer Res , vol.56 , Issue.20 , pp. 4778-4781
    • Lothe, R.A.1    Karhu, R.2    Mandahl, N.3
  • 36
    • 0344224273 scopus 로고    scopus 로고
    • Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization
    • Mechtersheimer G, Otano-Joos M, Ohl S, et al. Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization. Genes Chromosomes Cancer 1999;25(4):362-9
    • (1999) Genes Chromosomes Cancer , vol.25 , Issue.4 , pp. 362-369
    • Mechtersheimer, G.1    Otano-Joos, M.2    Ohl, S.3
  • 37
    • 0345552243 scopus 로고    scopus 로고
    • Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant
    • Schmidt H, Wurl P, Taubert H, et al. Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant. Genes Chromosomes Cancer 1999;25(3):205-11
    • (1999) Genes Chromosomes Cancer , vol.25 , Issue.3 , pp. 205-211
    • Schmidt, H.1    Wurl, P.2    Taubert, H.3
  • 38
    • 33746895189 scopus 로고    scopus 로고
    • Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    • Storlazzi CT, Brekke HR, Mandahl N, et al. Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours. J Pathol 2006;209(4):492-500
    • (2006) J Pathol , vol.209 , Issue.4 , pp. 492-500
    • Storlazzi, C.T.1    Brekke, H.R.2    Mandahl, N.3
  • 39
    • 0032506524 scopus 로고    scopus 로고
    • Control of apoptosis and mitotic spindle checkpoint by survivin
    • Li F, Ambrosini G, Chu EY, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998;396(6711):580-4
    • (1998) Nature , vol.396 , Issue.6711 , pp. 580-584
    • Li, F.1    Ambrosini, G.2    Chu, E.Y.3
  • 40
    • 0036570207 scopus 로고    scopus 로고
    • Regulation of microtubule stability and mitotic progression by survivin
    • Giodini A, Kallio MJ, Wall NR, et al. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res 2002;62(9):2462-7
    • (2002) Cancer Res , vol.62 , Issue.9 , pp. 2462-2467
    • Giodini, A.1    Kallio, M.J.2    Wall, N.R.3
  • 41
    • 1542438624 scopus 로고    scopus 로고
    • Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome
    • Skotheim RI, Kallioniemi A, Bjerkhagen B, et al. Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome. J Clin Oncol 2003;21(24):4586-91
    • (2003) J Clin Oncol , vol.21 , Issue.24 , pp. 4586-4591
    • Skotheim, R.I.1    Kallioniemi, A.2    Bjerkhagen, B.3
  • 42
    • 0036227720 scopus 로고    scopus 로고
    • Culprit and victim - DNA topoisomerase II
    • Kellner U, Sehested M, Jensen PB, et al. Culprit and victim - DNA topoisomerase II. Lancet Oncol 2002;3(4):235-43
    • (2002) Lancet Oncol , vol.3 , Issue.4 , pp. 235-243
    • Kellner, U.1    Sehested, M.2    Jensen, P.B.3
  • 43
    • 0036088222 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumors are t(X; 18)-negative sarcomas. Molecular analysis of 25 cases occurring in neurofibromatosis type 1 patients, using two different RT-PCR-based methods of detection
    • Coindre JM, Hostein I, Benhattar J, et al. Malignant peripheral nerve sheath tumors are t(X; 18)-negative sarcomas. Molecular analysis of 25 cases occurring in neurofibromatosis type 1 patients, using two different RT-PCR-based methods of detection. Mod Pathol 2002;15(6):589-92
    • (2002) Mod Pathol , vol.15 , Issue.6 , pp. 589-592
    • Coindre, J.M.1    Hostein, I.2    Benhattar, J.3
  • 44
    • 0028307836 scopus 로고
    • Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
    • Jacks T, Shih TS, Schmitt EM, et al. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nat Genet 1994;7(3):353-61
    • (1994) Nat Genet , vol.7 , Issue.3 , pp. 353-361
    • Jacks, T.1    Shih, T.S.2    Schmitt, E.M.3
  • 45
    • 0032763861 scopus 로고    scopus 로고
    • Cichowski K, Shih TS, Schmitt E, et al. Mouse models of tumor development in neurofibromatosis type 1. Science (New York, NY) 1999;286(5447):2172-6
    • Cichowski K, Shih TS, Schmitt E, et al. Mouse models of tumor development in neurofibromatosis type 1. Science (New York, NY) 1999;286(5447):2172-6
  • 46
    • 0037012848 scopus 로고    scopus 로고
    • Zhu Y, Ghosh P, Charnay P, et al. Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (New York, NY) 2002;296(5569):920-2
    • Zhu Y, Ghosh P, Charnay P, et al. Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (New York, NY) 2002;296(5569):920-2
  • 47
    • 0032786494 scopus 로고    scopus 로고
    • Vogel KS, Klesse LJ, Velasco-Miguel S, et al. Mouse tumor model for neurofibromatosis type 1. Science (New York, NY) 1999;286(5447):2176-9
    • Vogel KS, Klesse LJ, Velasco-Miguel S, et al. Mouse tumor model for neurofibromatosis type 1. Science (New York, NY) 1999;286(5447):2176-9
  • 48
    • 2442681924 scopus 로고    scopus 로고
    • Comparative pathology of nerve sheath tumors in mouse models and humans
    • Stemmer-Rachamimov AO, Louis DN, Nielsen GP, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Res 2004;64(10):3718-24
    • (2004) Cancer Res , vol.64 , Issue.10 , pp. 3718-3724
    • Stemmer-Rachamimov, A.O.1    Louis, D.N.2    Nielsen, G.P.3
  • 49
    • 33846309244 scopus 로고    scopus 로고
    • Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenografr model
    • Mahller YY, Vaikunth SS, Currier MA, et al. Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenografr model. Mol Ther 2007;15(2):279-86
    • (2007) Mol Ther , vol.15 , Issue.2 , pp. 279-286
    • Mahller, Y.Y.1    Vaikunth, S.S.2    Currier, M.A.3
  • 50
    • 35348997092 scopus 로고    scopus 로고
    • An orthotopic xenograft model of intraneural NF1 MPNST suggests a potential association between steroid hormones and tumor cell proliferation
    • Perrin GQ, Li H, Fishbein L, et al. An orthotopic xenograft model of intraneural NF1 MPNST suggests a potential association between steroid hormones and tumor cell proliferation. Lab Invest 2007;87(11):1092-102
    • (2007) Lab Invest , vol.87 , Issue.11 , pp. 1092-1102
    • Perrin, G.Q.1    Li, H.2    Fishbein, L.3
  • 51
    • 0036330022 scopus 로고    scopus 로고
    • Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms
    • Perry A, Kunz SN, Fuller CE, et al. Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms. J Neuropathol Exp Neurol 2002;61(8):702-9
    • (2002) J Neuropathol Exp Neurol , vol.61 , Issue.8 , pp. 702-709
    • Perry, A.1    Kunz, S.N.2    Fuller, C.E.3
  • 52
    • 0023838869 scopus 로고
    • Immunohistochemical evaluation of Leu-7, myelin basic-protein, S100-protein, glial-fibrillary acidic-protein, and LN3 immunoreactivity in nerve sheath tumors and sarcomas
    • Johnson MD, Glick AD, Davis BW. Immunohistochemical evaluation of Leu-7, myelin basic-protein, S100-protein, glial-fibrillary acidic-protein, and LN3 immunoreactivity in nerve sheath tumors and sarcomas. Arch Pathol Lab Med 1988;112(2):155-60
    • (1988) Arch Pathol Lab Med , vol.112 , Issue.2 , pp. 155-160
    • Johnson, M.D.1    Glick, A.D.2    Davis, B.W.3
  • 53
    • 0023829202 scopus 로고
    • Expression of glial fibrillary acidic protein (GFAP) in peripheral nerve sheath tumors. A comparative study of immunoreactivity of GFAP, vimentin, S-100 protein, and neurofilament in 38 schwannomas and 18 neurofibromas
    • Kawahara E, Oda Y, Ooi A, et al. Expression of glial fibrillary acidic protein (GFAP) in peripheral nerve sheath tumors. A comparative study of immunoreactivity of GFAP, vimentin, S-100 protein, and neurofilament in 38 schwannomas and 18 neurofibromas. Am J Surg Pathol 1988;12(2):115-20
    • (1988) Am J Surg Pathol , vol.12 , Issue.2 , pp. 115-120
    • Kawahara, E.1    Oda, Y.2    Ooi, A.3
  • 54
    • 0025894817 scopus 로고
    • Human peripheral nerve sheath neoplasm: Expression of Schwann cell-related markers and their relation to malignant transformation
    • Yasuda T, Sobue G, Ito T, et al. Human peripheral nerve sheath neoplasm: expression of Schwann cell-related markers and their relation to malignant transformation. Muscle Nerve 1991;14(9):812-9
    • (1991) Muscle Nerve , vol.14 , Issue.9 , pp. 812-819
    • Yasuda, T.1    Sobue, G.2    Ito, T.3
  • 55
    • 0020509519 scopus 로고
    • Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors
    • Weiss SW, Langloss JM, Enzinger FM. Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors. Lab Invest 1983;49(3):299-308
    • (1983) Lab Invest , vol.49 , Issue.3 , pp. 299-308
    • Weiss, S.W.1    Langloss, J.M.2    Enzinger, F.M.3
  • 56
    • 0023099684 scopus 로고
    • Malignant peripheral nerve sheath tumor. An immunohistochemical study of 62 cases
    • Wick MR, Swanson PE, Scheithauer BW, Manivel JC. Malignant peripheral nerve sheath tumor. An immunohistochemical study of 62 cases. Am J Clin Pathol 1987;87(4):425-33
    • (1987) Am J Clin Pathol , vol.87 , Issue.4 , pp. 425-433
    • Wick, M.R.1    Swanson, P.E.2    Scheithauer, B.W.3    Manivel, J.C.4
  • 57
    • 0025940735 scopus 로고
    • S-100 protein positive synovial sarcoma
    • Fisher C, Schofield JB. S-100 protein positive synovial sarcoma. Histopathology 1991;19(4):375-77
    • (1991) Histopathology , vol.19 , Issue.4 , pp. 375-377
    • Fisher, C.1    Schofield, J.B.2
  • 58
    • 0033490215 scopus 로고    scopus 로고
    • Usefulness of cytokeratin subsets for distinguishing monophasic synovial sarcoma from malignant peripheral nerve sheath tumor
    • Smith TA, Machen SK, Fisher C, Goldblum JR. Usefulness of cytokeratin subsets for distinguishing monophasic synovial sarcoma from malignant peripheral nerve sheath tumor. Am J Clin Pathol 1999;112(5):641-8
    • (1999) Am J Clin Pathol , vol.112 , Issue.5 , pp. 641-648
    • Smith, T.A.1    Machen, S.K.2    Fisher, C.3    Goldblum, J.R.4
  • 59
    • 0026607887 scopus 로고
    • Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells
    • Tohyama T, Lee VM, Rorke LB, et al. Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. Lab Invest 1992;66(3):303-13
    • (1992) Lab Invest , vol.66 , Issue.3 , pp. 303-313
    • Tohyama, T.1    Lee, V.M.2    Rorke, L.B.3
  • 60
    • 33846951844 scopus 로고    scopus 로고
    • Nestin expression as a new marker in malignant peripheral nerve sheath tumors
    • Shimada S, Tsuzuki T, Kuroda M, et al. Nestin expression as a new marker in malignant peripheral nerve sheath tumors. Pathol Int 2007;57:60-7
    • (2007) Pathol Int , vol.57 , pp. 60-67
    • Shimada, S.1    Tsuzuki, T.2    Kuroda, M.3
  • 61
    • 33646146940 scopus 로고    scopus 로고
    • Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma
    • Olsen SH, Thomas DG, Lucas DIL Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma. Mod Pathol 2006;19(5):659-68
    • (2006) Mod Pathol , vol.19 , Issue.5 , pp. 659-668
    • Olsen, S.H.1    Thomas, D.G.2    Lucas, D.I.L.3
  • 62
    • 0029781715 scopus 로고    scopus 로고
    • p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors
    • Halling KC, Scheithauer BW, Halling AC, et al. p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors. Am J Clin Pathol 1996;106(3):282-8
    • (1996) Am J Clin Pathol , vol.106 , Issue.3 , pp. 282-288
    • Halling, K.C.1    Scheithauer, B.W.2    Halling, A.C.3
  • 63
    • 0029131833 scopus 로고
    • Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant peripheral nerve sheath tumours
    • Kindblom LG, Ahlden M, Meis-Kindblom JM, Stenman G. Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant peripheral nerve sheath tumours. Virchows Arch 1995;427(1):19-26
    • (1995) Virchows Arch , vol.427 , Issue.1 , pp. 19-26
    • Kindblom, L.G.1    Ahlden, M.2    Meis-Kindblom, J.M.3    Stenman, G.4
  • 64
    • 0032963486 scopus 로고    scopus 로고
    • p53 and Ki-67 proliferating cell nuclear antigen in benign and malignant peripheral nerve sheath tumors in children
    • Liapis H, Marley EF, Lin Y, Dehner LP. p53 and Ki-67 proliferating cell nuclear antigen in benign and malignant peripheral nerve sheath tumors in children. Pediatr Dev Pathol 1999;2(4):377-84
    • (1999) Pediatr Dev Pathol , vol.2 , Issue.4 , pp. 377-384
    • Liapis, H.1    Marley, E.F.2    Lin, Y.3    Dehner, L.P.4
  • 65
    • 0032762177 scopus 로고    scopus 로고
    • Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: The emerging role of p27(kip) in malignant transformation of neurofibromas
    • Kourea HP, Cordon-Cardo C, Dudas M, et al. Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas. Am J Pathol 1999;155(6):1885-91
    • (1999) Am J Pathol , vol.155 , Issue.6 , pp. 1885-1891
    • Kourea, H.P.1    Cordon-Cardo, C.2    Dudas, M.3
  • 66
    • 0141571288 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumor: A comparison of grade, immunophenotype, and cell cycle/growth activation marker expression in sporadic and neurofibromatosis 1-related lesions
    • Zhou H, Coffin CM, Perkins SL, et al. Malignant peripheral nerve sheath tumor: a comparison of grade, immunophenotype, and cell cycle/growth activation marker expression in sporadic and neurofibromatosis 1-related lesions. Am J Surg Pathol 2003;27(10):1337-45
    • (2003) Am J Surg Pathol , vol.27 , Issue.10 , pp. 1337-1345
    • Zhou, H.1    Coffin, C.M.2    Perkins, S.L.3
  • 67
    • 34748915278 scopus 로고    scopus 로고
    • Expression of CyclinDl, p27kp-1, and bcl-2 in plexiform neurofibroma with and without malignant transformation in neurofibromatosis type 1
    • Thanakit V, Shuangshoti S, Ruangvejvorachai P. Expression of CyclinDl, p27kp-1, and bcl-2 in plexiform neurofibroma with and without malignant transformation in neurofibromatosis type 1. J Med Assoc Thai 2006;89(Suppl 3):S53-7
    • (2006) J Med Assoc Thai , vol.89 , Issue.SUPPL. 3
    • Thanakit, V.1    Shuangshoti, S.2    Ruangvejvorachai, P.3
  • 68
    • 33645806562 scopus 로고    scopus 로고
    • Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: Emmprin and membrane-type (MT) 1-MMP expressions are associated with malignant potential
    • Nabeshima K, Iwasaki H, Nishio J, et al. Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT) 1-MMP expressions are associated with malignant potential. Anticancer Res 2006;26(2B):1359-67
    • (2006) Anticancer Res , vol.26 , Issue.2 B , pp. 1359-1367
    • Nabeshima, K.1    Iwasaki, H.2    Nishio, J.3
  • 69
    • 34548215196 scopus 로고    scopus 로고
    • MMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors
    • New York, NY
    • Holtkamp N, Atallah I, Okuducu AF, et al. MMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors. Neoplasia (New York, NY) 2007;9(8):671-7
    • (2007) Neoplasia , vol.9 , Issue.8 , pp. 671-677
    • Holtkamp, N.1    Atallah, I.2    Okuducu, A.F.3
  • 70
    • 0037109028 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray
    • Nagayama S, Katagiri T, Tsunoda T, et al. Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray. Cancer Res 2002;62(20):5859-66
    • (2002) Cancer Res , vol.62 , Issue.20 , pp. 5859-5866
    • Nagayama, S.1    Katagiri, T.2    Tsunoda, T.3
  • 71
    • 34250680520 scopus 로고    scopus 로고
    • Gene expression analysis of soft tissue sarcomas: Characterization and reclassification of malignant fibmus histiocytoma
    • Nakayama R, Nemoto T, Takahashi H, et al. Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibmus histiocytoma. Mod Pathol 2007;20(7):749-59
    • (2007) Mod Pathol , vol.20 , Issue.7 , pp. 749-759
    • Nakayama, R.1    Nemoto, T.2    Takahashi, H.3
  • 72
    • 34047129837 scopus 로고    scopus 로고
    • Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: Hypoxia-induced transcription profile signifies metastatic potential
    • Francis P, Namlos HM, Muller C, et al. Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential. BMC Genomics 2007;8:73
    • (2007) BMC Genomics , vol.8 , pp. 73
    • Francis, P.1    Namlos, H.M.2    Muller, C.3
  • 73
    • 0742324551 scopus 로고    scopus 로고
    • Differentially expressed genes in neurofibrornatosis 1-associated neurofibrornas and malignant peripheral nerve sheath tumors
    • Holtkamp N, Mautner VF, Friedrich RE, et al. Differentially expressed genes in neurofibrornatosis 1-associated neurofibrornas and malignant peripheral nerve sheath tumors. Acta Neuropathol 2004;107(2):159-68
    • (2004) Acta Neuropathol , vol.107 , Issue.2 , pp. 159-168
    • Holtkamp, N.1    Mautner, V.F.2    Friedrich, R.E.3
  • 74
    • 4143048946 scopus 로고    scopus 로고
    • Holtkamp N, Reuss DE, Atallah 1, et al. Subclassification of nerve sheath tumors by gene expression profiling. Brain Pathol (Zurich, Switzerland) 2004;14(3):258-64
    • Holtkamp N, Reuss DE, Atallah 1, et al. Subclassification of nerve sheath tumors by gene expression profiling. Brain Pathol (Zurich, Switzerland) 2004;14(3):258-64
  • 75
    • 2542524778 scopus 로고    scopus 로고
    • Molecular profiles of neurofibromatosis type 1 -associated plexiform neurofibromas: Identification of a gene expression signature of poor prognosis
    • Levy P, Bieche I, Leroy K, et al. Molecular profiles of neurofibromatosis type 1 -associated plexiform neurofibromas: identification of a gene expression signature of poor prognosis. Clin Cancer Res 2004; 10(10:3763-71
    • (2004) Clin Cancer Res , vol.10 , Issue.10 , pp. 3763-3771
    • Levy, P.1    Bieche, I.2    Leroy, K.3
  • 76
    • 0037012509 scopus 로고    scopus 로고
    • A Twist in face: Evolutionary comparison of Twist structure and function
    • Castanon I, Baylies MK. A Twist in face: evolutionary comparison of Twist structure and function. Gene 2002;287(1-2):11-22
    • (2002) Gene , vol.287 , Issue.1-2 , pp. 11-22
    • Castanon, I.1    Baylies, M.K.2
  • 77
    • 33645061486 scopus 로고    scopus 로고
    • Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath rumor cell lines and tissues
    • Miller SJ, Rangwala F, Williams J, et al. Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath rumor cell lines and tissues. Cancer Res 2006;66(5):2584-91
    • (2006) Cancer Res , vol.66 , Issue.5 , pp. 2584-2591
    • Miller, S.J.1    Rangwala, F.2    Williams, J.3
  • 78
    • 32544437208 scopus 로고    scopus 로고
    • cDNA microarray analysis of cancer associated gene expression profiles in malignant peripheral nerve sheath tumours
    • Karube K, Nabeshima K, Ishigum M, et al. cDNA microarray analysis of cancer associated gene expression profiles in malignant peripheral nerve sheath tumours. J Clin Pathol 2006;59(2):160-5
    • (2006) J Clin Pathol , vol.59 , Issue.2 , pp. 160-165
    • Karube, K.1    Nabeshima, K.2    Ishigum, M.3
  • 79
    • 33846858434 scopus 로고    scopus 로고
    • Levy P, Ripoche H, Laurendeau I, et at. Microarray-based identification of tenascin C and tenascin XB, genes possibty involved in tumorigenesis associated with neurofibromatosis type 1. Clin Cancer Res 2007;13(2 Pr 1)398-407
    • Levy P, Ripoche H, Laurendeau I, et at. Microarray-based identification of tenascin C and tenascin XB, genes possibty involved in tumorigenesis associated with neurofibromatosis type 1. Clin Cancer Res 2007;13(2 Pr 1)398-407
  • 80
    • 0028960378 scopus 로고
    • Cellular schwannorna. A clinicopathologic, DNA flow cytometric, and proliferation marker study of 70 patients
    • Casadei CP, Scheithauer BW, Hirose T, et al. Cellular schwannorna. A clinicopathologic, DNA flow cytometric, and proliferation marker study of 70 patients. Cancer 1995;75(5):1109-19
    • (1995) Cancer , vol.75 , Issue.5 , pp. 1109-1119
    • Casadei, C.P.1    Scheithauer, B.W.2    Hirose, T.3
  • 81
    • 0035133870 scopus 로고    scopus 로고
    • Turnorigenic properties of neurofibromin-deficient neurofibroma Schwann cells
    • Muiir D, Neubauer D, Lim IT, et al. Turnorigenic properties of neurofibromin-deficient neurofibroma Schwann cells. Am J Pathol 2001;158(2):501-13
    • (2001) Am J Pathol , vol.158 , Issue.2 , pp. 501-513
    • Muiir, D.1    Neubauer, D.2    Lim, I.T.3
  • 82
    • 7344222073 scopus 로고    scopus 로고
    • Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1
    • Klose A, Ahmadian MR, Schuelke M, et al. Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1. Hum Mol Genet 1998;7(8):1261-8
    • (1998) Hum Mol Genet , vol.7 , Issue.8 , pp. 1261-1268
    • Klose, A.1    Ahmadian, M.R.2    Schuelke, M.3
  • 83
    • 38549102668 scopus 로고    scopus 로고
    • The loss of Nfi transiently promotes self-renewal bur not tumorigenesis by neural crest stern cells
    • Joseph NM, Mosher JT, Buchstaller J, et al. The loss of Nfi transiently promotes self-renewal bur not tumorigenesis by neural crest stern cells. Cancer Cell 2008;13(2):129-40
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 129-140
    • Joseph, N.M.1    Mosher, J.T.2    Buchstaller, J.3
  • 84
    • 38549108007 scopus 로고    scopus 로고
    • Plexiform. and derrnal neurofibrornas and piginentation are caused by Nfl loss in desert hedgehog-expressing cells
    • Wu J, Williams JP, Rizvi TA, et al. Plexiform. and derrnal neurofibrornas and piginentation are caused by Nfl loss in desert hedgehog-expressing cells. Cancer Cell 2008; 13(2):105-16
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 105-116
    • Wu, J.1    Williams, J.P.2    Rizvi, T.A.3
  • 85
    • 41149100145 scopus 로고    scopus 로고
    • MicroRNA. expression signature of human sarcornas
    • Subramanian S, Lui WO, Lee CH, et al. MicroRNA. expression signature of human sarcornas. Oncogene 2007;27:2015-26
    • (2007) Oncogene , vol.27 , pp. 2015-2026
    • Subramanian, S.1    Lui, W.O.2    Lee, C.H.3
  • 86
    • 33947426098 scopus 로고    scopus 로고
    • Survivin: A promising rumor biomaker
    • Duffy MJ, O'Donovan N, Brennan Dj, et al. Survivin: a promising rumor biomaker. Cancer Lett 2007;249(1):49-60
    • (2007) Cancer Lett , vol.249 , Issue.1 , pp. 49-60
    • Duffy, M.J.1    O'Donovan, N.2    Brennan, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.