메뉴 건너뛰기




Volumn 7, Issue 2, 2010, Pages 191-196

The PACAP Receptor: A Novel Target for Migraine Treatment

Author keywords

drug targets; human experimental headache models; mast cell degranulation; Migraine; trigeminal nociceptive system; vasodilatation

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; NEUROPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2;

EID: 77953429357     PISSN: 19337213     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nurt.2010.02.003     Document Type: Article
Times cited : (87)

References (66)
  • 2
    • 68249102634 scopus 로고    scopus 로고
    • Finding New drug targets for the treatment of migraine attacks
    • Olesen J., Tfelt-Hansen P., and Ashina M. Finding New drug targets for the treatment of migraine attacks. Cephalalgia 29 (2009) 909-920
    • (2009) Cephalalgia , vol.29 , pp. 909-920
    • Olesen, J.1    Tfelt-Hansen, P.2    Ashina, M.3
  • 3
    • 67649598903 scopus 로고    scopus 로고
    • Origin of pain in migraine: evidence for peripheral sensitisation
    • Olesen J., Burstein R., Ashina M., and Tfelt-Hansen P. Origin of pain in migraine: evidence for peripheral sensitisation. Lancet Neurol 8 (2009) 679-690
    • (2009) Lancet Neurol , vol.8 , pp. 679-690
    • Olesen, J.1    Burstein, R.2    Ashina, M.3    Tfelt-Hansen, P.4
  • 4
    • 0033134787 scopus 로고    scopus 로고
    • Neuronal messengers and peptide receptors in the human sphenopalatine and otic ganglia
    • Uddman R., Tajti J., MÖller S., Sundler F., and Edvinsson L. Neuronal messengers and peptide receptors in the human sphenopalatine and otic ganglia. Brain Res 826 (1999) 193-199
    • (1999) Brain Res , vol.826 , pp. 193-199
    • Uddman, R.1    Tajti, J.2    MÖller, S.3    Sundler, F.4    Edvinsson, L.5
  • 5
    • 0035341124 scopus 로고    scopus 로고
    • Origin and co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat
    • Edvinsson L., Elsås T., Suzuki N., Shimizu T., and Lee T.J. Origin and co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat. Microsc Res Tech 53 (2001) 221-228
    • (2001) Microsc Res Tech , vol.53 , pp. 221-228
    • Edvinsson, L.1    Elsås, T.2    Suzuki, N.3    Shimizu, T.4    Lee, T.J.5
  • 6
    • 0027534182 scopus 로고
    • Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries
    • Nozaki K., Moskowitz M.A., Maynard K.I., et al. Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries. J Cereb Blood Flow Metab 13 (1993) 70-79
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 70-79
    • Nozaki, K.1    Moskowitz, M.A.2    Maynard, K.I.3
  • 7
    • 0025914846 scopus 로고
    • Anatomical basis for a parasympathetic and sensory innervation of the intracranial segment of the internal carotid artery in man: possible implication for vascular headache
    • Suzuki N., and Hardebo J.E. Anatomical basis for a parasympathetic and sensory innervation of the intracranial segment of the internal carotid artery in man: possible implication for vascular headache. J Neurol Sci 104 (1991) 19-31
    • (1991) J Neurol Sci , vol.104 , pp. 19-31
    • Suzuki, N.1    Hardebo, J.E.2
  • 9
  • 10
    • 58849084087 scopus 로고    scopus 로고
    • PACAP38 induces migraine-like attacks in patients with migraine without aura
    • Schytz H.W., Birk S., Wienecke T., Kruuse C., Olesen J., and Ashina M. PACAP38 induces migraine-like attacks in patients with migraine without aura. Brain 132 (2009) 16-25
    • (2009) Brain , vol.132 , pp. 16-25
    • Schytz, H.W.1    Birk, S.2    Wienecke, T.3    Kruuse, C.4    Olesen, J.5    Ashina, M.6
  • 11
    • 0024415355 scopus 로고
    • Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells
    • Miyata A., Arimura A., Dahl R.R., et al. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun 164 (1989) 567-574
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 567-574
    • Miyata, A.1    Arimura, A.2    Dahl, R.R.3
  • 12
    • 70349922918 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
    • Vaudry D., Falluel-Morel A., Bourgault S., et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev 61 (2009) 283-357
    • (2009) Pharmacol Rev , vol.61 , pp. 283-357
    • Vaudry, D.1    Falluel-Morel, A.2    Bourgault, S.3
  • 13
    • 0025841676 scopus 로고
    • Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes
    • Arimura A., Somogyvári-Vigh A., Miyata A., Mizuno K., Coy D.H., and Kitada C. Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes. Endocrinology 129 (1991) 2787-2789
    • (1991) Endocrinology , vol.129 , pp. 2787-2789
    • Arimura, A.1    Somogyvári-Vigh, A.2    Miyata, A.3    Mizuno, K.4    Coy, D.H.5    Kitada, C.6
  • 14
    • 0027454873 scopus 로고
    • Distribution, molecular characterization of pituitary adenylate cyclase-activating polypeptide and its precursor encoding messenger RNA in human and rat tissues
    • Ghatei M.A., Takahashi K., Suzuki Y., Gardiner J., Jones P.M., and Bloom S.R. Distribution, molecular characterization of pituitary adenylate cyclase-activating polypeptide and its precursor encoding messenger RNA in human and rat tissues. J Endocrinol 136 (1993) 159-166
    • (1993) J Endocrinol , vol.136 , pp. 159-166
    • Ghatei, M.A.1    Takahashi, K.2    Suzuki, Y.3    Gardiner, J.4    Jones, P.M.5    Bloom, S.R.6
  • 15
    • 0028888345 scopus 로고
    • Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus
    • Hannibal J., Mikkelsen J.D., Clausen H., Holst J.J., Wulff B.S., and Fahrenkrug J. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. Regul Pept 55 (1995) 133-148
    • (1995) Regul Pept , vol.55 , pp. 133-148
    • Hannibal, J.1    Mikkelsen, J.D.2    Clausen, H.3    Holst, J.J.4    Wulff, B.S.5    Fahrenkrug, J.6
  • 16
    • 0028905708 scopus 로고
    • Pituitary adenylate cyclase activating peptide-38 (PACAP-38), PACAP-27, and PACAP related peptide (PRP) in the rat median eminence and pituitary
    • Mikkelsen J.D., Hannibal J., Fahrenkrug J., Larsen P.J., Olcese J., and McArdle C. Pituitary adenylate cyclase activating peptide-38 (PACAP-38), PACAP-27, and PACAP related peptide (PRP) in the rat median eminence and pituitary. J Neuroendocrinol 7 (1995) 47-55
    • (1995) J Neuroendocrinol , vol.7 , pp. 47-55
    • Mikkelsen, J.D.1    Hannibal, J.2    Fahrenkrug, J.3    Larsen, P.J.4    Olcese, J.5    McArdle, C.6
  • 17
    • 0033036503 scopus 로고    scopus 로고
    • Messenger molecules and receptor mRNA in the human trigeminal ganglion
    • Tajti J., Uddman R., Möller S., Sundler F., and Edvinsson L. Messenger molecules and receptor mRNA in the human trigeminal ganglion. J Auton Nerv Syst 76 (1999) 176-183
    • (1999) J Auton Nerv Syst , vol.76 , pp. 176-183
    • Tajti, J.1    Uddman, R.2    Möller, S.3    Sundler, F.4    Edvinsson, L.5
  • 18
    • 0036260865 scopus 로고    scopus 로고
    • Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2
    • Uddman R., Tajti J., Hou M., Sundler F., and Edvinsson L. Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2. Cephalalgia 22 (2002) 112-116
    • (2002) Cephalalgia , vol.22 , pp. 112-116
    • Uddman, R.1    Tajti, J.2    Hou, M.3    Sundler, F.4    Edvinsson, L.5
  • 19
    • 0034048147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions
    • Vaudry D., Gonzalez B.J., Basille M., Yon L., Fournier A., and Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52 (2000) 269-324
    • (2000) Pharmacol Rev , vol.52 , pp. 269-324
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Yon, L.4    Fournier, A.5    Vaudry, H.6
  • 20
    • 0029101230 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons
    • Mulder H., Uddman R., Moller K., et al. Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons. Regul Pept 59 (1995) 121-128
    • (1995) Regul Pept , vol.59 , pp. 121-128
    • Mulder, H.1    Uddman, R.2    Moller, K.3
  • 21
    • 7144263741 scopus 로고    scopus 로고
    • International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide
    • Harmar A.J., Arimura A., Gozes I., et al. International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol Rev 50 (1998) 265-270
    • (1998) Pharmacol Rev , vol.50 , pp. 265-270
    • Harmar, A.J.1    Arimura, A.2    Gozes, I.3
  • 22
    • 60849086453 scopus 로고    scopus 로고
    • VPAC and PAC receptors: from ligands to function
    • Dickson L., and Finlayson K. VPAC and PAC receptors: from ligands to function. Pharmacol Ther 121 (2009) 294-316
    • (2009) Pharmacol Ther , vol.121 , pp. 294-316
    • Dickson, L.1    Finlayson, K.2
  • 24
    • 0037171104 scopus 로고    scopus 로고
    • Distribution of mRNA for VIP and PACAP receptors in human cerebral arteries and cranial ganglia
    • Knutsson M., and Edvinsson L. Distribution of mRNA for VIP and PACAP receptors in human cerebral arteries and cranial ganglia. Neuroreport 13 (2002) 507-509
    • (2002) Neuroreport , vol.13 , pp. 507-509
    • Knutsson, M.1    Edvinsson, L.2
  • 25
    • 19544392552 scopus 로고
    • Stimulation of the superior sagittal sinus causes extracranial release of PACAP
    • Zagami A.S., Edvinsson L., HK L., and Goadsby P.J. Stimulation of the superior sagittal sinus causes extracranial release of PACAP. Cephalalgia 15 Suppl 14 (1995) 109
    • (1995) Cephalalgia , vol.15 , Issue.SUPPL. 14 , pp. 109
    • Zagami, A.S.1    Edvinsson, L.2    HK, L.3    Goadsby, P.J.4
  • 26
    • 0041527022 scopus 로고    scopus 로고
    • 2003 Wolff Award: Possible parasympathetic contributions to peripheral and central sensitization during migraine
    • Yarnitsky D., Goor-Aryeh I., Bajwa Z.H., et al. 2003 Wolff Award: Possible parasympathetic contributions to peripheral and central sensitization during migraine. Headache 43 (2003) 704-714
    • (2003) Headache , vol.43 , pp. 704-714
    • Yarnitsky, D.1    Goor-Aryeh, I.2    Bajwa, Z.H.3
  • 27
    • 0029994155 scopus 로고    scopus 로고
    • Intranasal lidocaine for treatment of migraine: a randomized, double-blind, controlled trial
    • Maizels M., Scott B., Cohen W., and Chen W. Intranasal lidocaine for treatment of migraine: a randomized, double-blind, controlled trial. JAMA 276 (1996) 319-321
    • (1996) JAMA , vol.276 , pp. 319-321
    • Maizels, M.1    Scott, B.2    Cohen, W.3    Chen, W.4
  • 28
    • 0032734056 scopus 로고    scopus 로고
    • Morphological and functional demonstration of rat dura mater mast cell-neuron interactions in vitro and in vivo
    • Rozniecki J.J., Dimitriadou V., Lambracht-Hall M., Pang X., and Theoharides T.C. Morphological and functional demonstration of rat dura mater mast cell-neuron interactions in vitro and in vivo. Brain Res 849 (1999) 1-15
    • (1999) Brain Res , vol.849 , pp. 1-15
    • Rozniecki, J.J.1    Dimitriadou, V.2    Lambracht-Hall, M.3    Pang, X.4    Theoharides, T.C.5
  • 30
    • 0025765727 scopus 로고
    • Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan
    • Friberg L., Olesen J., Iversen H.K., and Sperling B. Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan. Lancet 338 (1991) 13-17
    • (1991) Lancet , vol.338 , pp. 13-17
    • Friberg, L.1    Olesen, J.2    Iversen, H.K.3    Sperling, B.4
  • 31
    • 0027510648 scopus 로고
    • PACAP, a VIP-like peptide: immunohistochemical localization and effect upon cat pial arteries and cerebral blood flow
    • Uddman R., Goadsby P.J., Jansen I., and Edvinsson L. PACAP, a VIP-like peptide: immunohistochemical localization and effect upon cat pial arteries and cerebral blood flow. J Cereb Blood Flow Metab 13 (1993) 291-297
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 291-297
    • Uddman, R.1    Goadsby, P.J.2    Jansen, I.3    Edvinsson, L.4
  • 32
    • 0028963358 scopus 로고
    • The effects of pituitary adenylate cyclase-activating polypeptide on cerebral arteries and vertebral artery blood flow in anesthetized dogs
    • Seki Y., Suzuki Y., Baskaya M.K., et al. The effects of pituitary adenylate cyclase-activating polypeptide on cerebral arteries and vertebral artery blood flow in anesthetized dogs. Eur J Pharmacol 275 (1995) 259-266
    • (1995) Eur J Pharmacol , vol.275 , pp. 259-266
    • Seki, Y.1    Suzuki, Y.2    Baskaya, M.K.3
  • 33
    • 67650340411 scopus 로고    scopus 로고
    • The in vivo effect of VIP, PACAP-38 and PACAP-27 and mRNA expression of their receptors in rat middle meningeal artery
    • Boni L.J., Ploug K.B., Olesen J., Jansen-Olesen I., and Gupta S. The in vivo effect of VIP, PACAP-38 and PACAP-27 and mRNA expression of their receptors in rat middle meningeal artery. Cephalalgia 29 (2009) 837-847
    • (2009) Cephalalgia , vol.29 , pp. 837-847
    • Boni, L.J.1    Ploug, K.B.2    Olesen, J.3    Jansen-Olesen, I.4    Gupta, S.5
  • 34
    • 33947251213 scopus 로고    scopus 로고
    • The effect of intravenous PACAP38 on cerebral hemodynamics in healthy volunteers
    • Birk S., Sitarz J.T., Petersen K.A., et al. The effect of intravenous PACAP38 on cerebral hemodynamics in healthy volunteers. Regul Pept 140 (2007) 185-191
    • (2007) Regul Pept , vol.140 , pp. 185-191
    • Birk, S.1    Sitarz, J.T.2    Petersen, K.A.3
  • 35
    • 77953469986 scopus 로고    scopus 로고
    • Expression studies and pharmacological characterization of VIP and PACAP receptors in the cerebral circulation of the rat
    • (abstract PO316)
    • Baun M., Olesen J., and Jansen-Olesen I. Expression studies and pharmacological characterization of VIP and PACAP receptors in the cerebral circulation of the rat. Cephalalgia 29 Suppl 1 (2009) 133 (abstract PO316)
    • (2009) Cephalalgia , vol.29 , Issue.SUPPL. 1 , pp. 133
    • Baun, M.1    Olesen, J.2    Jansen-Olesen, I.3
  • 36
    • 77953394493 scopus 로고    scopus 로고
    • Pharmacological characterization and mRNA expression studies of VIP and PACAP receptors in human coronary arteries
    • (abstract PO315)
    • Baun M., Chan K.Y., Olesen J., Jansen-Olesen I., Gupta S., and Maassen Van Den Brink A. Pharmacological characterization and mRNA expression studies of VIP and PACAP receptors in human coronary arteries. Cephalalgia 29 Suppl 1 (2009) 132 (abstract PO315)
    • (2009) Cephalalgia , vol.29 , Issue.SUPPL. 1 , pp. 132
    • Baun, M.1    Chan, K.Y.2    Olesen, J.3    Jansen-Olesen, I.4    Gupta, S.5    Maassen Van Den Brink, A.6
  • 37
    • 65649086106 scopus 로고    scopus 로고
    • Migraine pain, meningeal inflammation, and mast cells
    • Levy D. Migraine pain, meningeal inflammation, and mast cells. Curr Pain Headache Rep 13 (2009) 237-240
    • (2009) Curr Pain Headache Rep , vol.13 , pp. 237-240
    • Levy, D.1
  • 40
    • 0029149168 scopus 로고
    • Histamine induces migraine via the H1-receptor. Support for the NO hypothesis of migraine
    • Lassen L.H., Thomsen L.L., and Olesen J. Histamine induces migraine via the H1-receptor. Support for the NO hypothesis of migraine. Neuroreport 6 (1995) 1475-1479
    • (1995) Neuroreport , vol.6 , pp. 1475-1479
    • Lassen, L.H.1    Thomsen, L.L.2    Olesen, J.3
  • 41
    • 34249742660 scopus 로고    scopus 로고
    • Mast cell degranulation activates a pain pathway underlying migraine headache
    • Levy D., Burstein R., Kainz V., Jakubowski M., and Strassman A.M. Mast cell degranulation activates a pain pathway underlying migraine headache. Pain 130 (2007) 166-176
    • (2007) Pain , vol.130 , pp. 166-176
    • Levy, D.1    Burstein, R.2    Kainz, V.3    Jakubowski, M.4    Strassman, A.M.5
  • 42
    • 34547137890 scopus 로고    scopus 로고
    • Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators
    • Zhang X.C., Strassman A.M., Burstein R., and Levy D. Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators. J Pharmacol Exp Ther 322 (2007) 806-812
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 806-812
    • Zhang, X.C.1    Strassman, A.M.2    Burstein, R.3    Levy, D.4
  • 43
    • 38649084996 scopus 로고    scopus 로고
    • Neuropeptides activate human mast cell degranulation and chemokine production
    • Kulka M., Sheen C.H., Tancowny B.P., Grammer L.C., and Schleimer R.P. Neuropeptides activate human mast cell degranulation and chemokine production. Immunology 123 (2008) 398-410
    • (2008) Immunology , vol.123 , pp. 398-410
    • Kulka, M.1    Sheen, C.H.2    Tancowny, B.P.3    Grammer, L.C.4    Schleimer, R.P.5
  • 44
    • 0032432937 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) is localized in human dermal neurons and causes histamine release from skin mast cells
    • Odum L., Petersen L.J., Skov P.S., and Ebskov L.B. Pituitary adenylate cyclase activating polypeptide (PACAP) is localized in human dermal neurons and causes histamine release from skin mast cells. Inflamm Res 47 (1998) 488-492
    • (1998) Inflamm Res , vol.47 , pp. 488-492
    • Odum, L.1    Petersen, L.J.2    Skov, P.S.3    Ebskov, L.B.4
  • 45
    • 0030983609 scopus 로고    scopus 로고
    • Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide
    • Ottosson A., and Edvinsson L. Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide. Cephalalgia 17 (1997) 166-174
    • (1997) Cephalalgia , vol.17 , pp. 166-174
    • Ottosson, A.1    Edvinsson, L.2
  • 46
    • 33751082695 scopus 로고    scopus 로고
    • A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology
    • Dickson L., Aramori I., McCulloch J., Sharkey J., and Finlayson K. A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology. Neuropharmacology 51 (2006) 1086-1098
    • (2006) Neuropharmacology , vol.51 , pp. 1086-1098
    • Dickson, L.1    Aramori, I.2    McCulloch, J.3    Sharkey, J.4    Finlayson, K.5
  • 47
    • 0037082222 scopus 로고    scopus 로고
    • Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors
    • Levy D., and Strassman A.M. Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors. J Physiol 538 (2002) 483-493
    • (2002) J Physiol , vol.538 , pp. 483-493
    • Levy, D.1    Strassman, A.M.2
  • 48
    • 0029863069 scopus 로고    scopus 로고
    • Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons
    • Ingram S.L., and Williams J.T. Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons. J Physiol 492 Pt 1 (1996) 97-106
    • (1996) J Physiol , vol.492 , Issue.PART 1 , pp. 97-106
    • Ingram, S.L.1    Williams, J.T.2
  • 49
    • 77953365828 scopus 로고    scopus 로고
    • 1 receptor antagonists inhibit activation of the parasympathetic outflow to the cranial vasculature to prevent autonomic responses and neuronal firing in the trigeminocervical complex
    • (abstract PO310)
    • 1 receptor antagonists inhibit activation of the parasympathetic outflow to the cranial vasculature to prevent autonomic responses and neuronal firing in the trigeminocervical complex. Cephalalgia 29 Suppl 1 (2009) 130 (abstract PO310)
    • (2009) Cephalalgia , vol.29 , Issue.SUPPL. 1 , pp. 130
    • Akerman, S.1    Goadsby, P.J.2
  • 50
    • 0034988854 scopus 로고    scopus 로고
    • Neuropeptide localization in the "migraine generator" region of the human brainstem
    • Tajti J., Uddman R., and Edvinsson L. Neuropeptide localization in the "migraine generator" region of the human brainstem. Cephalalgia 21 (2001) 96-101
    • (2001) Cephalalgia , vol.21 , pp. 96-101
    • Tajti, J.1    Uddman, R.2    Edvinsson, L.3
  • 51
    • 0018138322 scopus 로고
    • Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems
    • Basbaum A.I., Clanton C.H., and Fields H.L. Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems. J Comp Neurol 178 (1978) 209-224
    • (1978) J Comp Neurol , vol.178 , pp. 209-224
    • Basbaum, A.I.1    Clanton, C.H.2    Fields, H.L.3
  • 52
    • 0029012866 scopus 로고
    • Brain stem activation in spontaneous human migraine attacks
    • Weiller C., May A., Limmroth V., et al. Brain stem activation in spontaneous human migraine attacks. Nat Med 1 (1995) 658-660
    • (1995) Nat Med , vol.1 , pp. 658-660
    • Weiller, C.1    May, A.2    Limmroth, V.3
  • 53
    • 33746462702 scopus 로고    scopus 로고
    • New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice
    • Hashimoto H., Shintani N., and Baba A. New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice. Ann N Y Acad Sci 1070 (2006) 75-89
    • (2006) Ann N Y Acad Sci , vol.1070 , pp. 75-89
    • Hashimoto, H.1    Shintani, N.2    Baba, A.3
  • 54
    • 0030988527 scopus 로고    scopus 로고
    • Capsaicin-evoked release of pituitary adenylate cyclase activating peptide (PACAP) and calcitonin gene-related peptide (CGRP) from rat spinal cord in vivo
    • Zhang Y., Malmberg A.B., Yaksh T.L., Sjölund B., Sundler F., and Håkanson R. Capsaicin-evoked release of pituitary adenylate cyclase activating peptide (PACAP) and calcitonin gene-related peptide (CGRP) from rat spinal cord in vivo. Regul Pept 69 (1997) 83-87
    • (1997) Regul Pept , vol.69 , pp. 83-87
    • Zhang, Y.1    Malmberg, A.B.2    Yaksh, T.L.3    Sjölund, B.4    Sundler, F.5    Håkanson, R.6
  • 55
    • 7244255891 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain
    • Mabuchi T., Shintani N., Matsumura S., et al. Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain. J Neurosci 24 (2004) 7283-7291
    • (2004) J Neurosci , vol.24 , pp. 7283-7291
    • Mabuchi, T.1    Shintani, N.2    Matsumura, S.3
  • 56
    • 0242475309 scopus 로고    scopus 로고
    • Central sensitization and LTP: do pain and memory share similar mechanisms?
    • Ji R.R., Kohno T., Moore K.A., and Woolf C.J. Central sensitization and LTP: do pain and memory share similar mechanisms?. Trends Neurosci 26 (2003) 696-705
    • (2003) Trends Neurosci , vol.26 , pp. 696-705
    • Ji, R.R.1    Kohno, T.2    Moore, K.A.3    Woolf, C.J.4
  • 58
    • 42749089298 scopus 로고    scopus 로고
    • Central pituitary adenylate cyclase 1 receptors modulate nociceptive behaviors in both inflammatory and neuropathic pain states
    • Davis-Taber R., Baker S., Lehto S.G., et al. Central pituitary adenylate cyclase 1 receptors modulate nociceptive behaviors in both inflammatory and neuropathic pain states. J Pain 9 (2008) 449-456
    • (2008) J Pain , vol.9 , pp. 449-456
    • Davis-Taber, R.1    Baker, S.2    Lehto, S.G.3
  • 59
    • 0036842877 scopus 로고    scopus 로고
    • Modulation of nociceptive transmission by pituitary adenylate cyclase activating polypeptide in the spinal cord of the mouse
    • Ohsawa M., Brailoiu G.C., Shiraki M., Dun N.J., Paul K., and Tseng L.F. Modulation of nociceptive transmission by pituitary adenylate cyclase activating polypeptide in the spinal cord of the mouse. Pain 100 (2002) 27-34
    • (2002) Pain , vol.100 , pp. 27-34
    • Ohsawa, M.1    Brailoiu, G.C.2    Shiraki, M.3    Dun, N.J.4    Paul, K.5    Tseng, L.F.6
  • 60
    • 33746056915 scopus 로고    scopus 로고
    • Vasoactive intestinal polypeptide evokes only a minimal headache in healthy volunteers
    • Hansen J.M., Sitarz J., Birk S., et al. Vasoactive intestinal polypeptide evokes only a minimal headache in healthy volunteers. Cephalalgia 26 (2006) 992-1003
    • (2006) Cephalalgia , vol.26 , pp. 992-1003
    • Hansen, J.M.1    Sitarz, J.2    Birk, S.3
  • 61
    • 38649107079 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide causes marked cephalic vasodilation, but does not induce migraine
    • Rahmann A., Wienecke T., Hansen J.M., Fahrenkrug J., Olesen J., and Ashina M. Vasoactive intestinal peptide causes marked cephalic vasodilation, but does not induce migraine. Cephalalgia 28 (2008) 226-236
    • (2008) Cephalalgia , vol.28 , pp. 226-236
    • Rahmann, A.1    Wienecke, T.2    Hansen, J.M.3    Fahrenkrug, J.4    Olesen, J.5    Ashina, M.6
  • 62
    • 77953379817 scopus 로고    scopus 로고
    • Cutaneous nociception and neurogenic inflammation evoked by VIP and PACAP38: a human experimental study
    • (abstract LBPO08)
    • Schytz H.W., Holst H., Arendt-Nielsen L., Olesen L., and Ashina M. Cutaneous nociception and neurogenic inflammation evoked by VIP and PACAP38: a human experimental study. Cephalalgia 29 12 (2009) 1358 (abstract LBPO08)
    • (2009) Cephalalgia , vol.29 , Issue.12 , pp. 1358
    • Schytz, H.W.1    Holst, H.2    Arendt-Nielsen, L.3    Olesen, L.4    Ashina, M.5
  • 63
    • 0027384993 scopus 로고
    • Passage of pituitary adenylate cyclase activating polypeptide1-27 and pituitary adenylate cyclase activating polypeptide1-38 across the blood-brain barrier
    • Banks W.A., Kastin A.J., Komaki G., and Arimura A. Passage of pituitary adenylate cyclase activating polypeptide1-27 and pituitary adenylate cyclase activating polypeptide1-38 across the blood-brain barrier. J Pharmacol Exp Ther 267 (1993) 690-696
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 690-696
    • Banks, W.A.1    Kastin, A.J.2    Komaki, G.3    Arimura, A.4
  • 65
    • 33847671313 scopus 로고    scopus 로고
    • 8-37, a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery
    • 8-37, a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery. Br J Pharmacol 150 (2007) 633-640
    • (2007) Br J Pharmacol , vol.150 , pp. 633-640
    • Edvinsson, L.1    Nilsson, E.2    Jansen-Olesen, I.3
  • 66
    • 42249087655 scopus 로고    scopus 로고
    • MK-0974 Protocol 004 Study Group. Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
    • Ho T.W., Mannix L.K., Fan X., et al. MK-0974 Protocol 004 Study Group. Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine. Neurology 70 (2008) 1304-1312
    • (2008) Neurology , vol.70 , pp. 1304-1312
    • Ho, T.W.1    Mannix, L.K.2    Fan, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.