Pituitary adenylate cyclase activating polypeptide (PACAP) is localized in human dermal neurons and causes histamine release from skin mast cells

Inflammation Research

Volumn 47, Issue 12, 1998, Pages 488-492

  Odum L ^a,b   Petersen, L J ^b   Skov, P S ^c   Ebskov, L B ^b  

^a ROSKILDE HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

Human; Immunohistochemistry; Mast cells; Microdialysis; Neuropeptides; Skin

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; HISTAMINE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; NEUROPEPTIDE; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

ARTICLE; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAST CELL; MICRODIALYSIS; SKIN CELL; SWEAT GLAND;

CALCITONIN GENE-RELATED PEPTIDE; HISTAMINE RELEASE; HUMANS; IMMUNOHISTOCHEMISTRY; KINETICS; MAST CELLS; NEURONS; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; SKIN; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0032432937     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050363     Document Type: Article

References (33)

1. Keränen U, Järvinen H, Kärkkäinen P, Kiviluoto T, Kivilaakso E, Soinila S. Substance P - an underlying factor for pounchitis? Dig Dis Sci 1996; 41:1665-71.
2. Kolansinski SL, Haines KA, Siegel EL, Cronstein BN, Abramson SB. Neuropeptides and inflammation. A. Somatostatin analog as a selective antagonist of neutrophic activation by substance P. Arthritis Rheum 1992;35:369-75.
3. Foreman JC. Peptides and neurogenic inflammation. Br Med Bull 1987;43:386-400.
4. Goetzl EJ, Sreedharan SP. Mediators of communication and adaption in the neuroendocrine and immune systems. FASEB J 1992;6:2646-52.
5. Bienenstock J, Macqueen G, Sestini P, Marshall JS, Stead RH, Perdue MH. Inflammatory cell mechanisms. Mast cell/nerve interactions in vitro and in vivo. Am Rev Respir Dis 1991;153:S55-8.
6. Foreman JC. Non-immunological stimuli of mast cells and basophil leucocytes. In:Foreman JC, editor. Immunopharmacology of mast cells and basophils. London: Academic Press, 1993:57-69.
7. Church MK, Lowman MA, Robinson C, Holgate ST, Benyon RC. Interaction of neuropeptides with human mast cells. Int Arch Allergy Appl Immunol 1989;88:70-8.
8. Naukkarinen A Harvima IT, Aalto M-L, Harvima RJ, Horsmanheimo M. Quantitive analysis of contact sites between mast cells and sensory nerves in cutaneous psoriasis and lichen planus based on a histochemical double staining technique. Arch Dermatol Res 1991;283:433-7.
9. Miyata A, Arimura A, Dahl RR, Minamino N, Uehara A, Jiang L, et al. Isolation of a novel 38 residue hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun 1989;164: 567-74.
10. Miyata A, Jiang LJ, Dahl RD, Kitada C, Kubo K, Fujino M, et al. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem Biophys Res Commun 1990;170:643-8.
11. Arimura A, Shioda S. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: Neuroendocrine and endocrine interaction. Front Neuroendocrinol 1995;16:53-88.
12. Arimura A, Somogyvari-Vigh A, Miyata A, Mizuno K, Coy DH, Kitada C. Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes. Endocrinology 1991;129:2787-9.
13. Gras S, Hannibal J, Georg B, Fahrenkrug J. Transient periovulatory expression of pituitary adenylate cyclase activating peptide in rat ovarian cells. Endocrinology 1996;137:4779-85.
14. Benyon RC, Robinson C, Church MK. Differential release of histamine and eicosanoids from human skin mast cells activated by IgE-dependent and non-immunological stimuli. Br J Pharmacol 1989;97:898-904.
15. Bewly AP, Skinner S, Petersen LJ, Keefe M, Church MK. Vasoactive intestinal peptide (VIP) induce histamine release from human cutaneous mast cells in vitro. Skin Pharmacol 1996;9:143-4.
16. Mori T, Kawashima T, Beppu Y, Takagi K. Histamine release induced by pituitary adenylate cyclase activating polypeptide from rat peritoneal mast cells. Arzneim-Forsch/Drug Res 1994;44: 1044-6.
17. Petersen LJ, Poulsen LK, Søndergaard J, Skov PS. The use of cutaneous microdialysis to measure substances P-included histamine release in intact human skin in vivo. J Allergy Clin Immunol 1994;94:773-83.
18. Petersen LJ, Brasso K, Pryds M, Skov PS. Histamine release in intact human skin by monocyte chemoattractant factor-1, RANTES, macrophage inflammatory protein-1α, stem cell factor, anti-IgG, and codeine as d ertermined by an ex vivo skin microdialysis technique. J Allergy Clin Immunol 1996;98:790-6.
19. Petersen LJ, Church MK, Skov PS. Histamine is released in the weal but not the flare following challenge of human skin in vivo: A microdialysis study. Clin Exp Allergy 1997;27:284-95.
20. Skov PS, Norn S, Weeke B. A new method for detectiing histamine release. Agents Actions 1984;14:414-6.
21. Hannibal J, Mikkelsen JD, Clausen H, Hoist JJ, Wulff BS, Fahrenkrug J. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. Regul Pept 1995;55:133-48.
22. Fahrenkrug J, Buhl T, Hannibal J. PreproPACAP-derived peptides occur in VIP-producing tumours and co-exist with VIP. Regul Pept 1995;58:89-98.
23. Lowman MA, Benyon RC, Church MK. Characterization of neuropeptide-induced histamine release from human dispersed skin mast cells. Br J Pharmacol 1988;95:121-30.
24. Mousli M, Hugli TE, Landry Y, Bronner C. Peptidergic pathway in human skin and rat peritoneal mast cell activation. Immunopharmacol 1994;27: 1-11.
25. Huttunen M, Harvima IT, Ackermann L, Harvima RJ, Naukkarinen A, Horsmanheimo, M. Neuropeptide- and capsaicin-induced histamine release in skin monitored with the micordialysis technique. Acta Derm Venereol 1996;76:205-9.
26. Fuller RW, Conradson TB, Dixon CMS, Crossmann DC, Barnes PJ. Sensory neuropeptide effects in human skin. Br J Pharmacol 1987;92:7781-8.
27. Wagner S, Klaffschenkel RA, Becker HD, Williams RM. Evidence of VIP and NPY receptors in a human mast cell line. Regul Pept 1996;64:202.
28. Lutz EM, Sheward WJ, West KM, Morrow JA, Fink, G, Harmar AJ. The VIP2 receptor: molecular characterization of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett 1993;334:3-8.
29. Eedy DJ, Shaw C, Johnston CF, Buchanan KD. The regional distribution of neuropeptides in human skin us assessed by radioimmunoassay and high-performance liquid chromatography. Clin Exp Dermatol 1994;19:463-72.
30. Navarro X, Verdu E, Wendelscafer-Crabh G, Kennedy WR. Innervation of cutaneous structures in the mouse hind paw: a confocal microscopy immunohistochemical study. J Neuroscience Res 1995;41:111-20.
31. Graf AH, Schiechl A, Hacker GW, Hauser-Kronberger C, Steiner H, Arimura A, Sundler F, Staudach A, Dietze O. Helospectin and pituriatry adnylate cyclase activating polypeptide in the human vagina. Regul Pept 1995;55:277-86.
32. Schmeltz M, Luz O, Averbeck B, Bickel A. Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis. Neurosci Lett 1997;230:117-20.
33. Petersen LJ, Winge K, Brodin E, Skov PS. No release of histamine and substance P in capsaicin-induced neurogenic inflammation in intact human skin in vivo: A microdialysis study. Clin Exp Allergy 1997;27: 957-65.