Central Pituitary Adenylate Cyclase 1 Receptors Modulate Nociceptive Behaviors in Both Inflammatory and Neuropathic Pain States

Journal of Pain

Volumn 9, Issue 5, 2008, Pages 449-456

  Davis Taber, Rachel ^a   Baker, Scott ^a   Lehto, Sonya G ^a   Zhong, Chengmin ^a   Surowy, Carol S ^a   Faltynek, Connie R ^a   Scott, Victoria E ^a   Honore, Prisca ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

antiallodynic; antihyperanalgesic; intrathecal; PAC1 receptor antagonist; PACAP 6 38

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 6-38; VASOACTIVE INTESTINAL POLYPEPTIDE ANTAGONIST; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOSE RESPONSE; HYPERALGESIA; MALE; MOTOR PERFORMANCE; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PROTEIN FUNCTION; RAT;

ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; INFLAMMATION; INJECTIONS, SPINAL; LIGATION; MALE; NEURALGIA; NEURONS, AFFERENT; NOCICEPTORS; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; PERIPHERAL NERVES; PERIPHERAL NERVOUS SYSTEM DISEASES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I;

EID: 42749089298     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2008.01.329     Document Type: Article

References (32)

1. Abbott F.V., Franklin K.B., and Westbrook R.F. The formalin test: Scoring properties of the first and second phases of the pain response in rats. Pain 60 (1995) 91-102
2. Arimura A. Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems. Jpn J Physiol 48 (1998) 301-331
3. Bennett G.J., and Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33 (1988) 87-107
4. Bockaert J., and Pin J.P. Molecular tinkering of G protein-coupled receptors: An evolutionary success. EMBO J 18 (1999) 1723-1729
5. Bove S.E., Calcaterra S.L., Brooker R.M., Huber C.M., Guzman R.E., Juneau P.L., Schrier D.J., and Kilgore K.S. Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. Osteoarth Cartil 11 (2003) 821-830
6. Davis-Taber R.A., and Scott V.E. Transcriptional profiling of dorsal root ganglia in a neuropathic pain model using microarray and laser capture microdissection. Drug Dev Res 67 (2006) 308-330
7. Dickinson T., and Fleetwood-Walker S.M. VIP and PACAP: Very important in pain?. TIPS 20 (1999) 324-329
8. Dickinson T., Mitchell R., Robberecht P., and Fleetwood-Walker S.M. The role of VIP/PACAP receptor subtypes in spinal somatosensory processing in rats with an experimental peripheral mononeuropathy. Neuropharmacology 38 (1999) 167-180
9. Garry E.M., Delaney A., Blackburn-Munro G., Dickinson T., Moss A., Nakalembe I., Robertson D.C., Rosie R., Robberecht P., Mitchell R., and Fleetwood-Walker S.M. Activation of p38 and p42/44 MAP kinase in neuropathic pain: Involvement of VPAC2 and NK2 receptors and mediation by spinal glia. Mol Cell Neurosci 30 (2005) 523-537
10. 1 receptor. NeuroReport 12 (2001) 2215-2219
11. Jongsma Wallin H., Pettersson L.M., Verge V.M., and Danielsen N. Effect of anti-nerve growth factor treatment on pituitary adenylate cyclase activating polypeptide expression in adult sensory neurons exposed to adjuvant induced inflammation. Neuroscience 120 (2003) 325-331
12. Kim S.H., and Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50 (1992) 355-363
13. Levine E.S., and Kolb J.E. Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons. J Neurosci Res 62 (2000) 357-362
14. Lin S.Y., Wu K., Levine E.S., Mount H.T., Suen P.C., and Black I.B. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain Res Mol Brain Res 55 (1998) 20-27
15. Mabuchi T., Shintani N., Matsumura S., Okuda-Ashitaka E., Hashimoto H., Muratani T., Minami T., Baba A., and Ito S. Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain. J Neurosci 24 (2004) 9283-9291
16. q, protein kinase C, and activation of Src. J Neurosci 25 (2005) 11374-11384
17. Macsai M., Pataki I., Toth G., and Szabo G. The effects of pituitary adenylate cyclase-activating polypeptide on acute and chronic morphine actions in mice. Regul Peptides 109 (2002) 57-62
18. Martin M., Otto C., Santamarta M.T., Torrecilla M., Pineda J., Schutz G., and Maldonaldo R. Morphine withdrawal is modified in pituitary adenylate cyclase-activating polypeptide type I-receptor-deficient mice. Mol Brain Res 110 (2003) 109-118
19. McDougall J.J., Watkins L., and Li Z. Vasoactive intestinal peptide (VIP) is a modulator of joint pain in a rat model of osteoarthritis. Pain 123 (2006) 98-105
20. Merighi A., Carmignoto G., Gobbo S., Lossi L., Salio C., Vergnano A.M., and Zonta M. Neurotrophins in spinal cord nociceptive pathways. Prog Brain Res 146 (2004) 291-321
21. Miyata A., Arimura A., Dahl R.R., Minamino N., Uehara A., Jiang L., Culler M.D., and Coy D.H. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun 164 (1989) 567-574
22. Narita M., Dun S.L., Dun N.J., and Tseng L.F. Hyperalgesia induced by pituitary adenylate cyclase-activating polypeptide in the mouse spinal cord. Eur J Pharmacol 311 (1996) 121-126
23. Ohsawa M., Brailoiu G.C., Shiraki M., Dun N.J., Paul K., and Tseng L.F. Modulation of nociceptive transmission by pituitary adenylate cyclase activating polypeptide in the spinal cord of the mouse. Pain 100 (2002) 27-34
24. Pellegri G., Magistretti P.J., and Martin J.-L. VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurons. Eur J Neurosci 10 (1998) 272-280
25. 1 receptor using a combinatorial approach with vasoactive intestinal peptide 6-23 as template. Mol Pharmacol 58 (2000) 1035-1041
26. Vaudry D., Gonzalez B.J., Basille M., Yon L., Fournier A., and Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52 (2000) 269-324
27. Xu X.-J., and Wiesenfeld-Hallin Z. Intrathecal pituitary adenylate cyclase activating polypeptide facilitates the spinal nociceptive flexor reflex in the rat. Neuroscience 72 (1996) 801-804
28. D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1*. J Biol Chem 278 (2003) 9630-9638
29. Yaksh T.L., and Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol Behav 17 (1976) 1031-1036
30. Yamamoto T., and Tatsuno I. Antinociceptive effect of intrathecally administered pituitary adenylate cyclase activating polypeptide (PACAP) on the rat formalin test. Neurosci Lett 184 (1995) 32-35
31. Zhang Y., Malmberg A.B., Sjolund B., and Yaksh T.L. The effect of pituitary adenylate cyclase activating peptide (PACAP) on the nociceptive formalin test. Neurosci Lett 207 (1996) 187-190
32. Zhang Y.Z., Hannibal J., Zhao Q., Moller K., Danielsen N., Fahrenkrug J., and Sundler F. Pituitary adenylate cyclase activating peptide expression in the rat dorsal root ganglia: up-regulation after peripheral nerve injury. Neuroscience 74 (1996) 1099-1110