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Volumn 1, Issue 6, 2009, Pages 905-912

Chimeric T cells for adoptive immunotherapy of cancer: Using what have we learned to plan for the future

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIBODY; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

EID: 77953413843     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.09.69     Document Type: Editorial
Times cited : (8)

References (48)
  • 1
    • 0035320526 scopus 로고    scopus 로고
    • A fresh look at tumor immunosurveillance and immunotherapy
    • Smyth MJ, Godfrey DI, Trapani JA: A fresh look at tumor immunosurveillance and immunotherapy. Nat. Immunol. 2(4), 293-299 (2001).
    • (2001) Nat. Immunol. , vol.2 , Issue.4 , pp. 293-299
    • Smyth, M.J.1    Godfrey, D.I.2    Trapani, J.A.3
  • 2
    • 0015288846 scopus 로고
    • Spontaneous regression of hepatic metastases from gastric carcinoma
    • Rosenberg SA, Fox E, Churchill WH: Spontaneous regression of hepatic metastases from gastric carcinoma. Cancer 29(2), 472-474 (1972).
    • (1972) Cancer , vol.29 , Issue.2 , pp. 472-474
    • Rosenberg, S.A.1    Fox, E.2    Churchill, W.H.3
  • 3
    • 0017150560 scopus 로고
    • Relationship of causative factors in spontaneous regression of cancer to immunologic factors possibly effective in cancer
    • Cole WH: Relationship of causative factors in spontaneous regression of cancer to immunologic factors possibly effective in cancer. J. Surg. Oncol. 8(5), 391-411 (1976).
    • (1976) J. Surg. Oncol. , vol.8 , Issue.5 , pp. 391-411
    • Cole, W.H.1
  • 4
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • Dudley ME, Wunderlich JR, Yang JC et al.: Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J. Clin. Oncol. 23(10), 2346-2357 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , Issue.10 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3
  • 5
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R et al.: Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J. Clin. Oncol. 26(32), 5233-5239 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.32 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3
  • 6
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, Dudley ME, Wunderlich JR et al.: Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314(5796), 126-129 (2006).
    • (2006) Science , vol.314 , Issue.5796 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 8
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of 'tumor escape' phenotypes
    • Khong HT, Restifo NP: Natural selection of tumor variants in the generation of 'tumor escape' phenotypes. Nat. Immunol. 3(11), 999-1005 (2002).
    • (2002) Nat. Immunol. , vol.3 , Issue.11 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 9
    • 38449094082 scopus 로고    scopus 로고
    • Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells
    • Thomas S, Xue SA, Cesco-Gaspere M et al.: Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells. J. Immunol. 179(9), 5803-5810 (2007).
    • (2007) J. Immunol. , vol.179 , Issue.9 , pp. 5803-5810
    • Thomas, S.1    Xue, S.A.2    Cesco-Gaspere, M.3
  • 10
    • 0035159470 scopus 로고    scopus 로고
    • Redirecting mouse CTL against colon carcinoma: Superior signaling efficacy of single-chain variable domain chimeras containing TCR-ζ vs Fcε RI-γ
    • Haynes NM, Snook MB, Trapani JA et al.: Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-ζ vs Fcε RI-γ. J. Immunol. 166(1), 182-187 (2001).
    • (2001) J. Immunol. , vol.166 , Issue.1 , pp. 182-187
    • Haynes, N.M.1    Snook, M.B.2    Trapani, J.A.3
  • 12
    • 11144241310 scopus 로고    scopus 로고
    • + tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy
    • + tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy. Blood 105(1), 241-250 (2005).
    • (2005) Blood , vol.105 , Issue.1 , pp. 241-250
    • Powell Jr., D.J.1    Dudley, M.E.2    Robbins, P.F.3    Rosenberg, S.A.4
  • 13
    • 0347505003 scopus 로고    scopus 로고
    • CD28-mediated co-stimulation: A quantitative support for TCR signalling
    • Acuto O, Michel F: CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3(12), 939-951 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.12 , pp. 939-951
    • Acuto, O.1    Michel, F.2
  • 15
    • 0035576250 scopus 로고    scopus 로고
    • Tumor-specific T cell activation by recombinant immunoreceptors: CD3ζ signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3ζ signaling receptor molecule
    • Hombach A, Wieczarkowiecz A, Marquardt T et al.: Tumor-specific T cell activation by recombinant immunoreceptors: CD3ζ signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3ζ signaling receptor molecule. J Immunol. 167(11), 6123-6131 (2001). (Pubitemid 33081538)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6123-6131
    • Hombach, A.1    Wieczarkowiecz, A.2    Marquardt, T.3    Heuser, C.4    Usai, L.5    Pohl, C.6    Seliger, B.7    Abken, H.8
  • 16
    • 0032531091 scopus 로고    scopus 로고
    • Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product
    • Finney HM, Lawson ADG, Bebbington CR, Weir ANC: Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product. J. Immunol. 161(6), 2791-2797 (1998).
    • (1998) J. Immunol. , vol.161 , Issue.6 , pp. 2791-2797
    • Finney, H.M.1    Lawson, A.D.G.2    Bebbington, C.R.3    Weir, A.N.C.4
  • 17
    • 0347994955 scopus 로고    scopus 로고
    • Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCRζ chain
    • Finney HM, Akbar AN, Lawson ADG: Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCRζ chain. J. Immunol. 172(1), 104-113 (2004).
    • (2004) J. Immunol. , vol.172 , Issue.1 , pp. 104-113
    • Finney, H.M.1    Akbar, A.N.2    Lawson, A.D.G.3
  • 18
    • 67649101753 scopus 로고    scopus 로고
    • Re-targeting T-cells against cancer by gene-transfer of tumor-reactive receptors
    • Marcu-Malina V, Van Dorp S, Kuball J: Re-targeting T-cells against cancer by gene-transfer of tumor-reactive receptors. Expert Opin. Biol. Ther. 9(5), 579-591 (2009).
    • (2009) Expert Opin. Biol. Ther. , vol.9 , Issue.5 , pp. 579-591
    • Marcu-Malina, V.1    Van Dorp, S.2    Kuball, J.3
  • 19
    • 28544448646 scopus 로고    scopus 로고
    • Supernatural T cells: Genetic modification of T cells for cancer therapy
    • Kershaw MH, Teng MW, Smyth MJ, Darcy PK: Supernatural T cells: genetic modification of T cells for cancer therapy. Nat. Rev. Immunol. 5(12), 928-940 (2005).
    • (2005) Nat. Rev. Immunol. , vol.5 , Issue.12 , pp. 928-940
    • Kershaw, M.H.1    Teng, M.W.2    Smyth, M.J.3    Darcy, P.K.4
  • 20
    • 0037348324 scopus 로고    scopus 로고
    • Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15
    • Brentjens RJ, Latouche JB, Santos E et al.: Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15. Nat. Med. 9(3), 279-286 (2003).
    • (2003) Nat. Med. , vol.9 , Issue.3 , pp. 279-286
    • Brentjens, R.J.1    Latouche, J.B.2    Santos, E.3
  • 21
    • 30044442768 scopus 로고    scopus 로고
    • Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice
    • Westwood JA, Smyth MJ, Teng MWL et al.: Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice. Proc. Natl Acad. Sci. USA 102(52), 19051-19056 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.52 , pp. 19051-19056
    • Westwood, J.A.1    Smyth, M.J.2    Teng, M.W.L.3
  • 22
    • 33845256434 scopus 로고    scopus 로고
    • T lymphocytes redirected against the κ light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells
    • DOI 10.1182/blood-2006-04-017061
    • Vera J, Savoldo B, Vigouroux S et al.: T lymphocytes redirected against the κ light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 108(12), 3890-3897 (2006). (Pubitemid 44864573)
    • (2006) Blood , vol.108 , Issue.12 , pp. 3890-3897
    • Vera, J.1    Savoldo, B.2    Vigouroux, S.3    Biagi, E.4    Pule, M.5    Rossig, C.6    Wu, J.7    Heslop, H.E.8    Rooney, C.M.9    Brenner, M.K.10    Dotti, G.11
  • 24
    • 3242765879 scopus 로고    scopus 로고
    • Gene-engineered T cells as a superior adjuvant therapy for metastatic cancer
    • Kershaw MH, Jackson JT, Haynes NM et al.: Gene-engineered T cells as a superior adjuvant therapy for metastatic cancer. J. Immunol. 173(3), 2143-2150 (2004).
    • (2004) J. Immunol. , vol.173 , Issue.3 , pp. 2143-2150
    • Kershaw, M.H.1    Jackson, J.T.2    Haynes, N.M.3
  • 25
    • 0037111240 scopus 로고    scopus 로고
    • Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation
    • Haynes NM, Trapani JA, Teng MW et al.: Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation. J. Immunol. 169(10), 5780-5786 (2002).
    • (2002) J. Immunol. , vol.169 , Issue.10 , pp. 5780-5786
    • Haynes, N.M.1    Trapani, J.A.2    Teng, M.W.3
  • 26
    • 33750699642 scopus 로고    scopus 로고
    • A Phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
    • Kershaw MH, Westwood JA, Parker LL et al.: A Phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin. Cancer Res. 12(20), 6106-6115 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , Issue.20 , pp. 6106-6115
    • Kershaw, M.H.1    Westwood, J.A.2    Parker, L.L.3
  • 27
    • 50549096284 scopus 로고    scopus 로고
    • Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
    • Till BG, Jensen MC, Wang J et al.: Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood 112(6) 2261-2271 (2008).
    • (2008) Blood , vol.112 , Issue.6 , pp. 2261-2271
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3
  • 28
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
    • Lamers CHJ, Sleijfer S, Vulto AG et al.: Treatment of metastatic renal cell carcinoma with autologous T lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J. Clin. Oncol. 24(13), E20-E22 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , Issue.13
    • Lamers, C.H.J.1    Sleijfer, S.2    Vulto, A.G.3
  • 29
    • 33947265424 scopus 로고    scopus 로고
    • Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
    • Park JR, Digiusto DL, Slovak M et al.: Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma. Mol. Ther. 15(4), 825-833 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.4 , pp. 825-833
    • Park, J.R.1    Digiusto, D.L.2    Slovak, M.3
  • 30
    • 55549145071 scopus 로고    scopus 로고
    • Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
    • Pule MA, Savoldo B, Myers GD et al.: Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat. Med. 14(11), 1264-1270 (2008).
    • (2008) Nat. Med. , vol.14 , Issue.11 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3
  • 31
    • 33749514632 scopus 로고    scopus 로고
    • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
    • Leen AM, Myers GD, Sili U et al.: Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat. Med. 12(10), 1160-1166 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.10 , pp. 1160-1166
    • Leen, A.M.1    Myers, G.D.2    Sili, U.3
  • 32
    • 0037448352 scopus 로고    scopus 로고
    • A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
    • Hacein-Bey-Abina S, Von Kalle C, Schmidt M et al.: A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348(3), 255-256. (2003).
    • (2003) N. Engl. J. Med. , vol.348 , Issue.3 , pp. 255-256
    • Hacein-Bey-Abina, S.1    Von Kalle, C.2    Schmidt, M.3
  • 33
    • 55249087037 scopus 로고    scopus 로고
    • Resistance of mature T cells to oncogene transformation
    • Newrzela S, Cornils K, Li Z et al.: Resistance of mature T cells to oncogene transformation. Blood 112(6), 2278-2286 (2008).
    • (2008) Blood , vol.112 , Issue.6 , pp. 2278-2286
    • Newrzela, S.1    Cornils, K.2    Li, Z.3
  • 34
    • 0026641562 scopus 로고
    • Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer
    • Donahue R, Kessler S, Bodine D et al.: Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J. Exp. Med. 176(4), 1125-1135 (1992).
    • (1992) J. Exp. Med. , vol.176 , Issue.4 , pp. 1125-1135
    • Donahue, R.1    Kessler, S.2    Bodine, D.3
  • 35
    • 0025534403 scopus 로고
    • Retroviral gene transfer using safe and efficient packaging cell lines
    • Markowitz D, Hesdorffer C, Ward M, Goff S, Bank A: Retroviral gene transfer using safe and efficient packaging cell lines. Ann. N. Y. Acad. Sci. 612(407), 407-414 (1990).
    • (1990) Ann. N. Y. Acad. Sci. , vol.612 , Issue.407 , pp. 407-414
    • Markowitz, D.1    Hesdorffer, C.2    Ward, M.3    Goff, S.4    Bank, A.5
  • 36
    • 0033918766 scopus 로고    scopus 로고
    • Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1)
    • Eckert HG, Kuhlcke K, Schilz AJ et al.: Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1). Bone Marrow Transplant 25 (Suppl. 2), S114-S117 (2000).
    • (2000) Bone Marrow Transplant , vol.25 , Issue.SUPPL. 2
    • Eckert, H.G.1    Kuhlcke, K.2    Schilz, A.J.3
  • 38
    • 0035989039 scopus 로고    scopus 로고
    • A Phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy
    • Deeks SG, Wagner B, Anton PA et al.: A Phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy. Mol. Ther. 5(6), 788-797 (2002).
    • (2002) Mol. Ther. , vol.5 , Issue.6 , pp. 788-797
    • Deeks, S.G.1    Wagner, B.2    Anton, P.A.3
  • 39
    • 4744355872 scopus 로고    scopus 로고
    • Escape from immunotherapy: Possible mechanisms that influence tumor regression/progression
    • Ahmad M, Rees RC, Ali SA: Escape from immunotherapy: possible mechanisms that influence tumor regression/progression. Cancer Immunol. Immunother. 53(10), 844-854 (2004).
    • (2004) Cancer Immunol. Immunother. , vol.53 , Issue.10 , pp. 844-854
    • Ahmad, M.1    Rees, R.C.2    Ali, S.A.3
  • 40
    • 0031723097 scopus 로고    scopus 로고
    • Eradication of residual disease by administration of leukemia-specific T cells after experimental allogeneic bone marrow transplantation
    • Zeis M, Uharek L, Glass B et al.: Eradication of residual disease by administration of leukemia-specific T cells after experimental allogeneic bone marrow transplantation. Exp. Hematol. 26(11), 1068-1073 (1998).
    • (1998) Exp. Hematol. , vol.26 , Issue.11 , pp. 1068-1073
    • Zeis, M.1    Uharek, L.2    Glass, B.3
  • 41
    • 36849048316 scopus 로고    scopus 로고
    • Donor lymphocyte infusion in the treatment of first hematological relapse after allogeneic stem-cell transplantation in adults with acute myeloid leukemia: A retrospective risk factors analysis and comparison with other strategies by the EBMT Acute Leukemia Working Party
    • Schmid C, Labopin M, Nagler A et al.: Donor lymphocyte infusion in the treatment of first hematological relapse after allogeneic stem-cell transplantation in adults with acute myeloid leukemia: a retrospective risk factors analysis and comparison with other strategies by the EBMT Acute Leukemia Working Party. J. Clin. Oncol. 25(31), 4938-4945 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , Issue.31 , pp. 4938-4945
    • Schmid, C.1    Labopin, M.2    Nagler, A.3
  • 43
    • 38149117105 scopus 로고    scopus 로고
    • Adoptive transfer of effector CD8 T cells derived from central memory cells establishes persistent T-cell memory in primates
    • Berger C, Jensen MC, Lansdorp PM, Gough M, Elliott C, Riddell SR: Adoptive transfer of effector CD8 T cells derived from central memory cells establishes persistent T-cell memory in primates. J. Clin. Invest. 118(1), 294-305 (2008).
    • (2008) J. Clin. Invest. , vol.118 , Issue.1 , pp. 294-305
    • Berger, C.1    Jensen, M.C.2    Lansdorp, P.M.3    Gough, M.4    Elliott, C.5    Riddell, S.R.6
  • 44
    • 77953440260 scopus 로고    scopus 로고
    • + T cells undergo functional polarization to effector and central memory cells in response to antigen exposure
    • Abstract 1531
    • + T cells undergo functional polarization to effector and central memory cells in response to antigen exposure. ASH Annual Meeting Abstracts 112(11) (2008) (Abstract 1531).
    • (2008) ASH Annual Meeting Abstracts , vol.112 , Issue.11
    • Neeson, P.1    Shin, A.2    Tai, T.3
  • 45
    • 60849098427 scopus 로고    scopus 로고
    • IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes
    • Kaneko S, Mastaglio S, Bondanza A et al.: IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes. Blood 113(5), 1006-1015 (2009).
    • (2009) Blood , vol.113 , Issue.5 , pp. 1006-1015
    • Kaneko, S.1    Mastaglio, S.2    Bondanza, A.3
  • 48
    • 12744253307 scopus 로고    scopus 로고
    • Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
    • Klebanoff CA, Khong HT, Antony PA, Palmer DC, Restifo NP: Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol. 26(2), 111-117 (2005).
    • (2005) Trends Immunol. , vol.26 , Issue.2 , pp. 111-117
    • Klebanoff, C.A.1    Khong, H.T.2    Antony, P.A.3    Palmer, D.C.4    Restifo, N.P.5


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