메뉴 건너뛰기




Volumn 9, Issue 6, 2010, Pages 1730-1739

Docetaxel-resistant prostate cancer cells remain sensitive to S-trityl-L-cysteine-mediated Eg5 inhibition

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; DOCETAXEL; KINESIN 5; KINESIN EG5; TRITYL DERIVATIVE; TRITYLCYSTEINE; UNCLASSIFIED DRUG;

EID: 77953399826     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-1103     Document Type: Article
Times cited : (28)

References (26)
  • 1
    • 50349090965 scopus 로고    scopus 로고
    • Intracellular transport and kinesin superfamily proteins, KIFs: Structure, function, and dynamics
    • Hirokawa N, Noda Y. Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics. Physiol Rev 2008;88:1089-118.
    • (2008) Physiol Rev , vol.88 , pp. 1089-1118
    • Hirokawa, N.1    Noda, Y.2
  • 3
    • 0029417238 scopus 로고
    • Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • Blangy A, Lane HA, d'Herin P, Harper M, Kress M, Nigg EA. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 1995;83:1159-69.
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1    Lane, H.A.2    D'Herin, P.3    Harper, M.4    Kress, M.5    Nigg, E.A.6
  • 5
    • 17144405643 scopus 로고    scopus 로고
    • Mitotic kinesins: Prospects for antimitotic drug discovery
    • DOI 10.2174/1568026053507697
    • Bergnes G, Brejc K, Belmont L. Mitotic kinesins: prospects for antimitotic drug discovery. Curr Top Med Chem 2005;5:127-45. (Pubitemid 40514510)
    • (2005) Current Topics in Medicinal Chemistry , vol.5 , Issue.2 , pp. 127-145
    • Bergnes, G.1    Brejc, K.2    Belmont, L.3
  • 6
    • 4644263812 scopus 로고    scopus 로고
    • In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities
    • DeBonis S, Skoufias DA, Lebeau L, et al. In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities. Mol Cancer Ther 2004;3:1079-90.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1079-1090
    • DeBonis, S.1    Skoufias, D.A.2    Lebeau, L.3
  • 9
    • 34250328223 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of l-cysteine derivatives as mitotic kinesin Eg5 inhibitors
    • DOI 10.1016/j.bmcl.2007.04.101, PII S0960894X07005318
    • Ogo N, Oishi S, Matsuno K, Sawada J, Fujii N, Asai A. Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors. Bioorg Med Chem Lett 2007;17:3921-4. (Pubitemid 46920939)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.14 , pp. 3921-3924
    • Ogo, N.1    Oishi, S.2    Matsuno, K.3    Sawada, J.-I.4    Fujii, N.5    Asai, A.6
  • 10
    • 41649110829 scopus 로고    scopus 로고
    • Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5
    • Debonis S, Skoufias DA, Indorato RL, et al. Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5. J Med Chem 2008;51:1115-25.
    • (2008) J Med Chem , vol.51 , pp. 1115-1125
    • Debonis, S.1    Skoufias, D.A.2    Indorato, R.L.3
  • 11
    • 0028238226 scopus 로고
    • In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate
    • Figg WD, Walls RG, Cooper MR, et al. In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate. Anticancer Drugs 1994;5:336-42.
    • (1994) Anticancer Drugs , vol.5 , pp. 336-342
    • Figg, W.D.1    Walls, R.G.2    Cooper, M.R.3
  • 15
    • 0027494237 scopus 로고
    • P53 Oncogene mutations in three human prostate cancer cell lines
    • Carroll AG, Voeller HJ, Sugars L, Gelmann EP. p53 oncogene mutations in three human prostate cancer cell lines. Prostate 1993;23:123-34. (Pubitemid 23289894)
    • (1993) Prostate , vol.23 , Issue.2 , pp. 123-134
    • Carroll, A.G.1    Voeller, H.J.2    Sugars, L.3    Gelmann, E.P.4
  • 16
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni JS, Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 1998;18:1055-64.
    • (1998) Mol Cell Biol , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 17
    • 0035945637 scopus 로고    scopus 로고
    • Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines
    • Tsuiki H, Nitta M, Tada M, Inagaki M, Ushio Y, Saya H. Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. Oncogene 2001;20:420-9.
    • (2001) Oncogene , vol.20 , pp. 420-429
    • Tsuiki, H.1    Nitta, M.2    Tada, M.3    Inagaki, M.4    Ushio, Y.5    Saya, H.6
  • 18
    • 44849127993 scopus 로고    scopus 로고
    • Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5
    • Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008;68:3269-76.
    • (2008) Cancer Res , vol.68 , pp. 3269-3276
    • Shi, J.1    Orth, J.D.2    Mitchison, T.3
  • 19
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
    • Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008;14:111-22.
    • (2008) Cancer Cell , vol.14 , pp. 111-122
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 20
    • 48749111500 scopus 로고    scopus 로고
    • The combination of docetaxel and the somatostatin analogue lanreotide on androgen-independent docetaxel-resistant prostate cancer: Experimental data
    • Lo Nigro C, Maffi M, Fischel JL, Formento P, Milano G, Merlano M. The combination of docetaxel and the somatostatin analogue lanreotide on androgen-independent docetaxel-resistant prostate cancer: experimental data. BJU Int 2008;102:622-7.
    • (2008) BJU Int , vol.102 , pp. 622-627
    • Lo Nigro, C.1    Maffi, M.2    Fischel, J.L.3    Formento, P.4    Milano, G.5    Merlano, M.6
  • 21
    • 50249169515 scopus 로고    scopus 로고
    • Effects of Eg5 knockdown on human prostate cancer xenograft growth and chemosensitivity
    • Hayashi N, Koller E, Fazli L, Gleave ME. Effects of Eg5 knockdown on human prostate cancer xenograft growth and chemosensitivity. Prostate 2008;68:1283-95.
    • (2008) Prostate , vol.68 , pp. 1283-1295
    • Hayashi, N.1    Koller, E.2    Fazli, L.3    Gleave, M.E.4
  • 23
    • 58149190803 scopus 로고    scopus 로고
    • Southwest Oncology Group phase II study of ispinesib in androgen-independent prostate cancer previously treated with taxanes
    • Beer TM, Goldman B, Synold TW, et al. Southwest Oncology Group phase II study of ispinesib in androgen-independent prostate cancer previously treated with taxanes. Clin Genitourin Cancer 2008;6:103-9.
    • (2008) Clin Genitourin Cancer , vol.6 , pp. 103-109
    • Beer, T.M.1    Goldman, B.2    Synold, T.W.3
  • 24
    • 65949119123 scopus 로고    scopus 로고
    • Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5
    • Rello-Varona S, Vitale I, Kepp O, et al. Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5. Cell Cycle 2009;8:1030-5.
    • (2009) Cell Cycle , vol.8 , pp. 1030-1035
    • Rello-Varona, S.1    Vitale, I.2    Kepp, O.3
  • 25
    • 22244459880 scopus 로고    scopus 로고
    • Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
    • Tao W, South VJ, Zhang Y, et al. Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 2005;8:49-59.
    • (2005) Cancer Cell , vol.8 , pp. 49-59
    • Tao, W.1    South, V.J.2    Zhang, Y.3
  • 26
    • 15744404844 scopus 로고    scopus 로고
    • Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells
    • Marcus AI, Peters U, Thomas SL, et al. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells. J Biol Chem 2005;280:11569-77.
    • (2005) J Biol Chem , vol.280 , pp. 11569-11577
    • Marcus, A.I.1    Peters, U.2    Thomas, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.