메뉴 건너뛰기




Volumn 5, Issue 4, 2010, Pages 589-596

Galactosylated nanocrystallites of insoluble anticancer drug for liver-targeting therapy: An in vitro evaluation

Author keywords

10 Hydroxycamptothecin; Anticancer; Asialoglycoprotein receptor; Drug delivery; Nanocrystallites

Indexed keywords

10 HYDROXYCAMPTOTHECIN; CHITOSAN; NANOCRYSTAL;

EID: 77953396145     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/nnm.10.27     Document Type: Article
Times cited : (61)

References (29)
  • 1
    • 0036742053 scopus 로고    scopus 로고
    • Poor aqueous solubility - An industry wide problem in drug discovery
    • Lipinski C: Poor aqueous solubility - an industry wide problem in drug discovery. Am. Pharm. Rev. 5, 82-85 (2002).
    • (2002) Am. Pharm. Rev. , vol.5 , pp. 82-85
    • Lipinski, C.1
  • 2
    • 0034461768 scopus 로고    scopus 로고
    • Drug-like properties and the cause of poor solubility and poor permeability
    • Lipinski CA: Drug-like properties and the cause of poor solubility and poor permeability. J. Pharmacol. Toxicol. Methods 44, 235-249 (2000).
    • (2000) J. Pharmacol. Toxicol. Methods , vol.44 , pp. 235-249
    • Lipinski, C.A.1
  • 3
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ: Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46, 3-26 (2001). (Pubitemid 33653411)
    • (2000) Advanced Drug Delivery Reviews , vol.46 , Issue.1-3 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 4
    • 60049096094 scopus 로고    scopus 로고
    • A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs
    • Chen MC, Tsai HW, Liu CT et al.: A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs. Biomaterials 30, 2102-2111 (2009).
    • (2009) Biomaterials , vol.30 , pp. 2102-2111
    • Chen, M.C.1    Tsai, H.W.2    Liu, C.T.3
  • 5
    • 34547864243 scopus 로고    scopus 로고
    • Drug delivery strategies for poorly water-soluble drugs
    • Fahr A, Liu X: Drug delivery strategies for poorly water-soluble drugs. Expert Opin. Drug Deliv. 4, 403-416 (2007).
    • (2007) Expert Opin. Drug Deliv. , vol.4 , pp. 403-416
    • Fahr, A.1    Liu, X.2
  • 6
    • 34447345669 scopus 로고    scopus 로고
    • One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier
    • Mizoe M, Beppu S, Ozeki T, Okada H: One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier. J. Control. Release 120, 205-210 (2007).
    • (2007) J. Control. Release , vol.120 , pp. 205-210
    • Mizoe, M.1    Beppu, S.2    Ozeki, T.3    Okada, H.4
  • 7
    • 47249128905 scopus 로고    scopus 로고
    • Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose
    • Yi T, Wan JL, Xu HB, Yang XL: Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose. Eur. J. Pharm. Sci. 34, 274-280 (2008).
    • (2008) Eur. J. Pharm. Sci. , vol.34 , pp. 274-280
    • Yi, T.1    Wan, J.L.2    Xu, H.B.3    Yang, X.L.4
  • 9
    • 0024560495 scopus 로고
    • Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: Evidence for a specific receptor site and a relation to antitumor activity
    • Jaxel C, Kohn KW, Wani MC, Wall ME, Pommier Y: Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. Cancer Res. 49, 1465-1469 (1989).
    • (1989) Cancer Res , vol.49 , pp. 1465-1469
    • Jaxel, C.1    Kohn, K.W.2    Wani, M.C.3    Wall, M.E.4    Pommier, Y.5
  • 10
    • 0036803284 scopus 로고    scopus 로고
    • Camptothecin delivery methods
    • Hatefi A, Amsden B: Camptothecin delivery methods. Pharm. Res. 19, 1389-1399 (2002).
    • (2002) Pharm. Res. , vol.19 , pp. 1389-1399
    • Hatefi, A.1    Amsden, B.2
  • 12
    • 0036304427 scopus 로고    scopus 로고
    • Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins
    • Garcia-Carbonero R, Supko JG: Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins. Clin. Cancer Res. 8, 641-661 (2002).
    • (2002) Clin. Cancer Res. , vol.8 , pp. 641-661
    • Garcia-Carbonero, R.1    Supko, J.G.2
  • 13
    • 42049121123 scopus 로고    scopus 로고
    • Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy
    • Min KH, Park P, Kim YS et al.: Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy. J. Control. Release 127, 208-218 (2008).
    • (2008) J. Control. Release , vol.127 , pp. 208-218
    • Min, K.H.1    Park, P.2    Kim, Y.S.3
  • 14
    • 0034925740 scopus 로고    scopus 로고
    • Thiolated polymers-thiomers: Development and in vitro evaluation of chitosan-thioglycolic acid conjugates
    • Kast CE, Bernkop-Schnurch AB: Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials 22, 2345-2352 (2001).
    • (2001) Biomaterials , vol.22 , pp. 2345-2352
    • Kast, C.E.1    Bernkop-Schnurch, A.B.2
  • 15
    • 0036009874 scopus 로고    scopus 로고
    • Molecular recognition by kluyveromyces of amphotericin B-loaded, galactose-tagged, poly (lactic acid) microspheres
    • Kassab R, Parrot-Lopez H, Fessi H, Menaucourt J, Bonaly R, Coulon J: Molecular recognition by kluyveromyces of amphotericin B-loaded, galactose-tagged, poly (lactic acid) microspheres. Bioorg. Med. Chem. 10, 1767-1775 (2002).
    • (2002) Bioorg. Med. Chem. , vol.10 , pp. 1767-1775
    • Kassab, R.1    Parrot-Lopez, H.2    Fessi, H.3    Menaucourt, J.4    Bonaly, R.5    Coulon, J.6
  • 16
    • 12944311177 scopus 로고    scopus 로고
    • Calcein-AM is a detector of intracellular oxidative activity
    • Uggeri J, Gatti R, Belletti S et al.: Calcein-AM is a detector of intracellular oxidative activity. Histochem. Cell Biol. 122, 499-505 (2004).
    • (2004) Histochem. Cell Biol. , vol.122 , pp. 499-505
    • Uggeri, J.1    Gatti, R.2    Belletti, S.3
  • 17
    • 0030040946 scopus 로고    scopus 로고
    • Detection of viable and non-viable cells in connective tissue explants using the fixable fluoroprobes 5-chloromethylfluorescein diacetate and ethidium homodimer-1
    • Poole CA, Brooks NH, Gilbert RT et al.: Detection of viable and non-viable cells in connective tissue explants using the fixable fluoroprobes 5-chloromethylfluorescein diacetate and ethidium homodimer-1. Connect. Tissue Res. 33, 233-241 (1996).
    • (1996) Connect. Tissue Res. , vol.33 , pp. 233-241
    • Poole, C.A.1    Brooks, N.H.2    Gilbert, R.T.3
  • 18
    • 23944480397 scopus 로고    scopus 로고
    • Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells
    • Managit C, Kawakami S, Yamashita F, Hashida M: Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. Int. J. Pharm. 301, 255-261 (2005).
    • (2005) Int. J. Pharm. , vol.301 , pp. 255-261
    • Managit, C.1    Kawakami, S.2    Yamashita, F.3    Hashida, M.4
  • 19
    • 41549117129 scopus 로고    scopus 로고
    • Design and synthesis of novel galactosylated polymers for liposomes as gene drug carriers targeting the hepatic asialoglycoprotein receptor
    • Wang SL, Yu FB, Jiang TY, Sun CS, Wang T, Zhang JH: Design and synthesis of novel galactosylated polymers for liposomes as gene drug carriers targeting the hepatic asialoglycoprotein receptor. J. Drug Target. 16, 233-242 (2008).
    • (2008) J. Drug Target. , vol.16 , pp. 233-242
    • Wang, S.L.1    Yu, F.B.2    Jiang, T.Y.3    Sun, C.S.4    Wang, T.5    Zhang, J.H.6
  • 20
    • 1542268858 scopus 로고    scopus 로고
    • Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier
    • Kim TH, Park IK, Nah JW, Choi YJ, Cho CS: Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. Biomaterials 25, 3783-3792 (2004).
    • (2004) Biomaterials , vol.25 , pp. 3783-3792
    • Kim, T.H.1    Park, I.K.2    Nah, J.W.3    Choi, Y.J.4    Cho, C.S.5
  • 21
    • 21544437607 scopus 로고    scopus 로고
    • Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector
    • Gao S, Chen J, Dong L, Ding Z, Yang YH, Zhang J: Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector. Eur. J. Pharm. Biopharm. 60, 327-334 (2005).
    • (2005) Eur. J. Pharm. Biopharm. , vol.60 , pp. 327-334
    • Gao, S.1    Chen, J.2    Dong, L.3    Ding, Z.4    Yang, Y.H.5    Zhang, J.6
  • 22
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL: Regulated portals of entry into the cell. Nature 422, 37-44 (2003).
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 23
    • 50149110878 scopus 로고    scopus 로고
    • The effect of particle design on cellular internalization pathways
    • Gratton SEA, Ropp PA, Pohlhaus PD et al.: The effect of particle design on cellular internalization pathways. Proc. Natl Acad. Sci. USA 105, 11613-11618 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 11613-11618
    • Gratton, S.E.A.1    Ropp, P.A.2    Pohlhaus, P.D.3
  • 24
    • 33644593889 scopus 로고    scopus 로고
    • Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery
    • Khalil IA, Kogure K, Akita H, Harashima H: Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol. Rev. 58, 32-45 (2006).
    • (2006) Pharmacol. Rev. , vol.58 , pp. 32-45
    • Khalil, I.A.1    Kogure, K.2    Akita, H.3    Harashima, H.4
  • 26
    • 65649142533 scopus 로고    scopus 로고
    • Mechanisms of drug sensitivity and resistance in cancer
    • O'Driscoll L: Mechanisms of drug sensitivity and resistance in cancer. Curr. Cancer Drug Targets 9, 250-251 (2009).
    • (2009) Curr. Cancer Drug Targets , vol.9 , pp. 250-251
    • O'Driscoll, L.1
  • 27
    • 39849107889 scopus 로고    scopus 로고
    • Cancer: Crossing over to drug resistance
    • Livingston DM, Silver DP: Cancer: crossing over to drug resistance. Nature 451, 1066-1067 (2008).
    • (2008) Nature , vol.451 , pp. 1066-1067
    • Livingston, D.M.1    Silver, D.P.2
  • 28
    • 25444438706 scopus 로고    scopus 로고
    • Targeted delivery of plasmid DNA into the nucleus of cells via nuclear localization signal peptide conjugated to DNA intercalating bis- and trisacridines
    • Shiraishi T, Hamzavi R, Nielsen PE: Targeted delivery of plasmid DNA into the nucleus of cells via nuclear localization signal peptide conjugated to DNA intercalating bis- and trisacridines. Bioconjug. Chem. 16, 1112-1116 (2005).
    • (2005) Bioconjug. Chem. , vol.16 , pp. 1112-1116
    • Shiraishi, T.1    Hamzavi, R.2    Nielsen, P.E.3
  • 29
    • 34147101146 scopus 로고    scopus 로고
    • Poly(l-lactide-co-glycolide) nanospheres conjugated with a nuclear localization signal for delivery of plasmid DNA
    • Jeon O, Lim HW, Lee M, Song SJ, Kim BS: Poly(l-lactide-co-glycolide) nanospheres conjugated with a nuclear localization signal for delivery of plasmid DNA. J. Drug Target. 15, 190-198 (2007).
    • (2007) J. Drug Target. , vol.15 , pp. 190-198
    • Jeon, O.1    Lim, H.W.2    Lee, M.3    Song, S.J.4    Kim, B.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.