Expanded CD23+/CD21hi B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy

Journal of Immunology

Volumn 184, Issue 11, 2010, Pages 6142-6150

  Li, Jie ^a   Kuzin, Igor ^b   Moshkani, Safiehkhatoon ^a,b   Proulx, Steven T ^a   Xing, Lianping ^a   Skrombolas, Denise ^a   Dunn, Robert ^c   Sanz, Iñaki ^a,b   Schwarz, Edward M ^a   Bottaro, Andrea ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; CD23 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; IMMUNOGLOBULIN M; ANTIRHEUMATIC AGENT; IMMUNOGLOBULIN E RECEPTOR; MONOCLONAL ANTIBODY; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B CELL DEPLETION; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE EROSION; CELL EXPANSION; CELL THERAPY; CLINICAL ASSESSMENT; DISEASE ASSOCIATION; DISEASE COURSE; KNEE ARTHRITIS; LYMPH NODE; LYMPHADENITIS; MOUSE; NONHUMAN; POLYCLONAL ACTIVATION; POPLITEAL LYMPH NODE; PRIORITY JOURNAL; SYNOVITIS; TRANSGENIC ANIMAL; ANIMAL; ARTHRITIS; C57BL MOUSE; CELL SEPARATION; CYTOLOGY; FLOW CYTOMETRY; GENETICS; HUMAN; IMMUNOLOGY; PATHOLOGY; RHEUMATOID ARTHRITIS; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CELL SEPARATION; FLOW CYTOMETRY; HUMANS; LYMPH NODES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, COMPLEMENT 3D; RECEPTORS, IGE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953367640     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903489     Document Type: Article

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