Application of platelet-rich plasma to enhance tissue repair

Operative Techniques in Orthopaedics

Volumn 20, Issue 2, 2010, Pages 98-105

  Wroblewski, Andrew P ^a   Mejia, Hector A ^a   Wright, Vonda J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Autologous blood; Growth factors; Musculoskeletal injuries; Platelet rich plasma

Indexed keywords

BUPIVACAINE; CALCIUM; COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C; THROMBIN; THROMBOCYTE FACTOR 4; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ACHILLES TENDON RUPTURE; ANKLE FRACTURE; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTHROSCOPIC SURGERY; ARTICLE; BIOCHEMISTRY; CELL GRANULE; CELL SEPARATION; FOOT FRACTURE; GEL; HUMAN; MUSCLE INJURY; NONHUMAN; PLATELET LEUKOCYTE GEL; PRIORITY JOURNAL; RISK FACTOR; ROTATOR CUFF RUPTURE; SPINE FUSION; TENDON INJURY; TENNIS ELBOW; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; THROMBOCYTOPHERESIS; TISSUE REPAIR;

EID: 77953353763     PISSN: 10486666     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.oto.2009.10.006     Document Type: Article

References (74)

1. Knighton D.R., Hunt T.K., Thakral K.K., et al. Role of platelets and fibrin in the healing sequence: An in vivo study of angiogenesis and collagen synthesis. Ann Surg 1982, 196:379-388.
2. Anitua E., Andia I., Ardanza B., et al. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004, 91:4-15.
3. Marx R.E. Platelet-rich plasma (PRP): What is PRP and what is not PRP?. Implant Dent 2001, 10:225-228.
4. Marx R.E. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg 2004, 62:489-496.
5. Fufa D., Shealy B., Jacobson M., et al. Activation of platelet-rich plasma using soluble type I collagen. J Oral Maxillofac Surg 2008, 66:684-690.
6. Mishra A., Woodall J., Vieira A. Treatment of tendon and muscle using platelet-rich plasma. Clin Sports Med 2009, 28:113-125.
7. Nho S.J., Yadav H., Shindle M.K., et al. Rotator cuff degeneration: Etiology and pathogenesis. Am J Sports Med 2008, 36:987-993.
8. Khaliq Y., Zhanel G.G. Fluoroquinolone-associated tendinopathy: A critical review of the literature. Clin Infect Dis 2003, 36:1404-1410.
9. Xu Y., Murrell G.A. The basic science of tendinopathy. Clin Orthop Relat Res 2008, 466:1528-1538.
10. Sharma P., Maffulli N. Tendon injury and tendinopathy: Healing and repair. J Bone Joint Surg Am 2005, 87:187-202.
11. Wurgler-Hauri C.C., Dourte L.M., Baradet T.C., et al. Temporal expression of 8 growth factors in tendon-to-bone healing in a rat supraspinatus model. J Shoulder Elbow Surg 2007, 16(suppl 5):S198-S203.
12. Lucarelli E., Beccheroni A., Donati D., et al. Platelet-derived growth factors enhance proliferation of human stromal stem cells. Biomaterials 2003, 24:3095-3100.
13. Woodall J., Tucci M., Mishra A., et al. Cellular effects of platelet rich plasma: A study on HL-60 macrophage-like cells. Biomed Sci Instrum 2007, 43:266-271.
14. Woodall J., Tucci M., Mishra A., et al. Cellular effects of platelet rich plasmainterleukin1 release from prp treated macrophages. Biomed Sci Instrum 2008, 44:489-494.
15. Kawamura S., Ying L., Kim H.J., et al. Macrophages accumulate in the early phase of tendon-bone healing. J Orthop Res 2005, 23:1425-1432.
16. Mishra A., Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med 2006, 34:1774-1778.
17. Randelli P.S., Arrigoni P., Cabitza P., et al. Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study. Disabil Rehabil 2008, 30:1584-1589.
18. Everts P.A., Devilee R.J., Brown Mahoney C., et al. Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome. A prospective randomized double-blind study. Eur Surg Res 2008, 40:203-210.
19. Anitua E., Sanchez M., Nurden A.T., et al. Reciprocal actions of platelet-secreted TGF-beta1 on the production of VEGF and HGF by human tendon cells. Plast Reconstr Surg 2007, 119:950-959.
20. Aspenberg P., Virchenko O. Platelet concentrate injection improves Achilles tendon repair in rats. Acta Orthop Scand 2004, 75:93-99.
21. Virchenko O., Aspenberg P. How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks? Interplay between early regeneration and mechanical stimulation. Acta Orthopade 2006, 77:806-812.
22. Jarvinen T.A., Jarvinen T.L., Kaariainen M., et al. Muscle injuries: Biology and treatment. Am J Sports Med 2005, 33:745-764.
23. Yokota K., Ishida O., Sunagawa T., et al. Platelet-rich plasma accelerated surgical angio-genesis in vascular-implanted necrotic bone: An experimental study in rabbits. Acta Orthop 2008, 79:106-110.
24. Sariguney Y., Yavuzer R., Elmas C., et al. Effect of platelet-rich plasma on peripheral nerve regeneration. J Reconstr Microsurg 2008, 24:159-167.
25. Shen W., Prisk V., Li Y., et al. Inhibited skeletal muscle healing in cyclooxygenase-2 gene-deficient mice: The role of PGE2 and PGF2alpha. J Appl Physiol 2006, 101:1215-1221.
26. Kasemkijwattana C., Menetrey J., Bosch P., et al. Use of growth factors to improve muscle healing after strain injury. Clin Orthop Relat Res 2000, 370:272-285.
27. Shen W., Li Y., Zhu J., et al. Interaction between macrophages, TGF-beta1, and the COX-2 pathway during the inflammatory phase of skeletal muscle healing after injury. J Cell Physiol 2008, 214:405-412.
28. Tayapongsak P., O'Brien D.A., Monteiro C.B., et al. Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg 1994, 52:161-165. discussion 166.
29. Marx R.E., Carlson E.R., Eichstaedt R.M., et al. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998, 85:638-646.
30. Lowery G.L., Kulkarni S., Pennisi A.E. Use of autologous growth factors in lumbar spinal fusion. Bone 1999, 25(suppl 2):47S-50S.
31. Kitoh H., Kitakoji T., Tsuchiya H., et al. Distraction osteogenesis of the lower extremity in patients with achondroplasia/hypochondroplasia treated with transplantation of culture-expanded bone marrow cells and platelet-rich plasma. J Pediatr Orthop 2007, 27:629-634.
32. Gandhi A., Bibbo C., Pinzur M. The role of platelet-rich plasma in foot and ankle surgery. Foot Ankle Clin 2005, 10:621-637. viii.
33. Murray M.M., Palmer M., Abreu E., et al. Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in skeletally immature animals: An in vivo study. J Orthop Res 2009, 27:639-645.
34. Spindler K.P., Murray M.M., Carey J.L., et al. The use of platelets to affect functional healing of an anterior cruciate ligament (ACL) autograft in a caprine ACL reconstruction model. J Orthop Res 2009, 27:631-638.
35. Eppley B.L., Woodell J.E., Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: Implications for wound healing. Plast Reconstr Surg 2004, 114:1502-1508.
36. Schilephake H. Bone growth factors in maxillofacial skeletal reconstruction. Int J Oral Maxillofac Surg 2002, 31:469-484.
37. Whitman D.H., Berry R.L., Green D.M. Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997, 55:1294-1299.
38. Raines E.W., Ross R. Platelet-derived growth factor. I. High yield purification and evidence for multiple forms. J Biol Chem 1982, 257:5154-5160.
39. Oates T.W., Rouse C.A., Cochran D.L. Mitogenic effects of growth factors on human periodontal ligament cells in vitro. J Periodontol 1993, 64:142-148.
40. Matsuda N., Lin W.L., Kumar N.M., et al. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 1992, 63:515-525.
41. Yang D., Chen J., Jing Z., et al. Platelet-derived growth factor (PDGF)-AA: A self-imposed cytokine in the proliferation of human fetal osteoblasts. Cytokines 2000, 12:1271-1274.
42. Hauschka P.V., Mavrakos A.E., Iafrati M.D., et al. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose. J Biol Chem 1986, 261:12665-12674.
43. Bucholz R., Einhorn T.A., Marsh J.L. Bone and joint healing. Bone Fractures in Adults 2006, 300-311. Lippincott Williams & Wilkins. R. Bucholz, J.D. Heckman, C. Court-Brown (Eds.).
44. Celeste A.J., Iannazzi J.A., Taylor R.C., et al. Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 1990, 87:9843-9847.
45. Wrana J.L., Maeno M., Hawrylyshyn B., et al. Differential effects of transforming growth factor-beta on the synthesis of extracellular matrix proteins by normal fetal rat calvarial bone cell populations. J Cell Biol 1988, 106:915-924.
46. Bonewald L.F., Mundy G.R. Role of transforming growth factor-beta in bone remodeling. Clin Orthop Relat Res 1990, 250:261-276.
47. Mohan S., Baylink D.J. Bone growth factors. Clin Orthop Relat Res 1991, 263:30-48.
48. Ten Dijke P., Hansen P., Iwata K.K., et al. Identification of another member of the transforming growth factor type beta gene family. Proc Natl Acad Sci USA 1988, 85:4715-4719.
49. Hock J.M., Centrella M., Canalis E. Insulin-like growth factor I has independent effects on bone matrix formation and cell replication. Endocrinology 1988, 122:254-260.
50. McCarthy T.L., Centrella M., Canalis E. Further biochemical and molecular characterization of primary rat parietal bone cell cultures. J Bone Miner Res 1988, 3:401-408.
51. Joseph B.K., Savage N.W., Daley T.J., et al. In situ hybridization evidence for a paracrine/autocrine role for insulin-like growth factor-I in tooth development. Growth Factors 1996, 13:11-17.
52. Einhorn T.A. The science of fracture healing. J Orthop Trauma 2005, 19(suppl 10):S4-S6.
53. Alsousou J., Thompson M., Hulley P., et al. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: A review of the literature. J Bone Joint Surg Br 2009, 91:987-996.
54. Maurer A.M., Zhou B., Han Z.C. Roles of platelet factor 4 in hematopoiesis and angiogenesis. Growth Factors 2006, 24:242-252.
55. Ferrara N., Gerber H.P. The role of vascular endothelial growth factor in angiogenesis. Acta Haematol 2001, 106:148-156.
56. Herbst R.S. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys 2004, 59(suppl 2):21-26.
57. Alsousou J., Thompson M., Hulley P., et al. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: A review of the literature. J Bone Joint Surg Br 2009, 91:987-996.
58. Awad A.S., Huang L., Ye H., et al. Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy. Am J Physiol Renal Physiol 2006, 290:F828-F837.
59. Cronstein B.M. Adenosine receptors and wound healing, revised. ScientificWorldJournal 2006, 6:984-991.
60. Nemeth Z.H., Lutz C.S., Csoka B., et al. Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism. J Immunol 2005, 175:8260-8270.
61. Cruz C.M., Rinna A., Forman H.J., et al. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem 2007, 282:2871-2879.
62. Parratt J.R., West G.B. Release of 5-hydroxytryptamine and histamine from tissues of the rat. J Physiol 1957, 137:179-192.
63. Sternberg E.M., Trial J., Parker C.W. Effect of serotonin on murine macrophages: Suppression of Ia expression by serotonin and its reversal by 5-HT2 serotonergic receptor antagonists. J Immunol 1986, 137:276-282.
64. Majno G., Gilmore V., Leventhal M. On the mechanism of vascular leakage caused by histaminetype mediators. A microscopic study in vivo. Circ Res 1967, 21:833-847.
65. Lansdown A.B. Calcium: A potential central regulator in wound healing in the skin. Wound Repair Regen 2002, 10:271-285.
66. Rutkowski J.L., Thomas J.M., Bering C.L., et al. Analysis of a rapid, simple, and inexpensive technique used to obtain platelet-rich plasma for use in clinical practice. J Oral Implantol 2008, 34:25-33.
67. Tamimi F.M., Montalvo S., Tresguerres I., et al. A comparative study of 2 methods for obtaining platelet-rich plasma. J Oral Maxillofac Surg 2007, 65:1084-1093.
68. Kevy S.V., Jacobson M.S. Comparison of methods for point of care preparation of autologous platelet gel. J Extra Corpor Technol 2004, 36:28-35.
69. Choi B.H., Zhu S.J., Kim B.Y., et al. Effect of platelet-rich plasma (PRP) concentration on the viability and proliferation of alveolar bone cells: An in vitro study. Int J Oral Maxillofac Surg 2005, 34:420-424.
70. Weibrich G., Kleis W.K. Curasan PRP kit vs. PCCS PRP system. Collection efficiency and platelet counts of two different methods for the preparation of platelet-rich plasma. Clin Oral Implants Res 2002, 13:437-443.
71. Weibrich G., Hansen T., Kleis W., et al. Effect of platelet concentration in platelet-rich plasma on peri-implant bone regeneration. Bone 2004, 34:665-671.
72. Weibrich G., Kleis W.K., Hafner G., et al. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 2002, 30:97-102.
73. Marlovits S., Mousavi M., Gabler C., et al. A new simplified technique for producing platelet-rich plasma: A short technical note. Eur Spine J 2004, 13(suppl 1):S102-S106.
74. Schoendorfer D.W., Williamson L.H., Sheckler V.L., et al. Platelet collection with the Autopheresis-C apheresis system. Vox Sang 1990, 58:100-105.