A new simplified technique for producing platelet-rich plasma: A short technical note

European Spine Journal

Volumn 13, Issue SUPPL. 1, 2004, Pages

  Marlovits, S ^a,b   Mousavi, M ^a   Gabler C ^a   Erdos J ^a   Vecsei V ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Bone healing; GPS; Growth factors; Platelet concentrate; Platelet rich plasma

Indexed keywords

FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; BONE GRAFT; BONE PROSTHESIS; DEVICE; FIBRIN CLOT; FRACTURE HEALING; HEMOSTASIS; HUMAN; LUMBAR SPINE; MALE; OSSIFICATION; PRIORITY JOURNAL; SOFT TISSUE; SPINE FUSION; TECHNIQUE; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; WOUND HEALING;

BLOOD LOSS, SURGICAL; BLOOD PLATELETS; BLOOD TRANSFUSION, AUTOLOGOUS; CELL SEPARATION; CENTRIFUGATION; GROWTH SUBSTANCES; HUMANS; PLATELET ACTIVATION; PLATELET TRANSFUSION; SPINE; WOUND HEALING;

EID: 8444246852     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-004-0715-3     Document Type: Article

References (24)

1. Bhanot S, Alex JC (2002) Current applications of platelet gels in facial plastic surgery. Facial Plast Surg; 18:27-33
2. Boden SD (2002) Overview of the biology of lumbar spine fusion and principles for selecting a bone graft substitute. Spine 27:826-31
3. Boden SD, Kang J, Sandhu H, Heller JG (2002) Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studies. Spine 27: 2662-2673
4. Canalis E (1985) Effect of growth factors on bone cell replication and differentiation. Clin Orthop 193:246-263
5. Canalis E, McCarthy TL, Centrella M (1989) Effects of platelet-derived growth factor on bone formation in vitro. J Cell Physiol 140:530-537
6. Caplan AI (1991) Mesenchymal stem cells. J Orthop Res 9:641-650
7. Gospodarowicz D (1983) Growth factors and their action in vivo and in vitro. J Pathol 141:201-233
8. Hotz G (1991) Alveolar ridge augmentation with hydroxylapatite using fibrin sealant for fixation. I. An experimental study. Int J Oral Maxillofac Surg 20: 204-207
9. Hotz G (1991) Alveolar ridge augmentation with hydroxylapatite using fibrin sealant for fixation. II. Clinical application. Int J Oral Maxillofac Surg 20: 208-213
10. Howes R, Bowness JM, Grotendorst GR, Martin GR, Reddi AH (1988) Platelet-derived growth factor enhances demineralized bone matrix-induced cartilage and bone formation. Calcif Tissue Int 42:34-38
11. Kasperk CH, Wergedal JE, Mohan S, Long DL, Lau KH, Baylink DJ (1990) Interactions of growth factors present in bone matrix with bone cells: effects on DNA synthesis and alkaline phosphatase. Growth Factors 3:147-158
12. Lowery GL, Kulkarni S, Pennisi AE (1999) Use of autologous growth factors in lumbar spinal fusion. Bone 25: 47S-50S
13. Margolis DJ, Kantor J, Santanna J, Strom BL, Berlin JA (2001) Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers. Diabetes Care 24:483-488
14. Martinowitz U, Spotnitz WD (1997) Fibrin tissue adhesives. Thromb Haemost 78:661-666
15. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR (1998) Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85:638-646
16. Matras H (1985) Fibrin seal: the state of the art. J Oral Maxillofac Surg 43: 605-611
17. Nielsen HM, Andreassen TT, Ledet T, Oxlund H (1994) Local injection of TGF-beta increases the strength of tibial fractures in the rat. Acta Orthop Scand 65:37-41
18. Nimni ME (1997) Polypeptide growth factors: targeted delivery systems. Biomaterials 18:1201-1225
19. Noda M, Camilliere JJ (1989) In vivo stimulation of bone formation by transforming growth factor-beta. Endocrinology 124:2991-2994
20. Schilephake H (2002) Bone growth factors in maxillofacial skeletal reconstruction. Int J Oral Maxillofac Surg 31:469-484
21. Slater M, Patava J, Kingham K, Mason RS (1995) Involvement of platelets in stimulating osteogenic activity. J Orthop Res 13:655-663
22. Sonnleitner D, Huemer P, Sullivan DY (2000) A simplified technique for producing platelet-rich plasma and platelet concentrate for intraoral bone grafting techniques: a technical note. Int J Oral Maxillofac Implants; 15:879-882
23. Vaccaro AR, Anderson DG, Toth CA (2002) Recombinant human osteogenic protein-1 (bone morphogenetic protein-7) as an osteoinductive agent in spinal fusion. Spine 27:S59-65
24. Whitman DH, Berry RL, Green DM (1997) Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 55:1294-1299