Early co-administration of vitamin E acetate and methylcobalamin improves thermal hyperalgesia and motor nerve conduction velocity following sciatic nerve crush injury in rats

Pharmacological Reports

Volumn 62, Issue 2, 2010, Pages 405-409

  Morani, Aashish S ^a   Bodhankar, Subhash L ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Methylcobalamin; Motor nerve conduction velocity; Neuropathic pain; Sciatic nerve crush injury; Thermal hyperalgesia; Vitamin E acetate

Indexed keywords

ALPHA TOCOPHEROL; MECOBALAMIN; PLACEBO; CYANOCOBALAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EARLY INTERVENTION; HYPERALGESIA; LATENT PERIOD; MALE; MOTOR NERVE CONDUCTION; NERVE CRUSH; NONHUMAN; RAT; SCIATIC NERVE; WITHDRAWAL REFLEX; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; MOTONEURON; NERVE CONDUCTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SCIATIC NEUROPATHY; WISTAR RAT;

ANIMALS; HYPERALGESIA; MALE; MOTOR NEURONS; NERVE CRUSH; NEURAL CONDUCTION; RATS; RATS, WISTAR; SCIATIC NERVE; SCIATIC NEUROPATHY; VITAMIN B 12; VITAMIN E;

EID: 77953297665     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(10)70281-4     Document Type: Article

References (34)

1. Aabdallah, D, Eid NI: Possible neuroprotective effects of lecithin and α-tocopherol alone or in combination against ischemia/reperfusion insult in rat brain. J Biochem Mol Toxicol, 2004, 18, 273-278.
2. Aktoz T, Aydogdu N, Alagol B, Yalcin O, Huseyinova G, Atakan IH: The protective effects of melatonin and vitamin E against renal ischemia-reperfusion injury in rats. Ren Fail, 2007, 29, 535-542.
3. Al Moutaery K, Arshaduddin M, Tariq M, Al Deeb S: Functional recovery and vitamin E level following sciatic nerve crush injury in normal and diabetic rats. Int J Neurosci, 1998, 96, 245-254.
4. Attal N, Filliatreau G, Perrot S, Jazat F, Di Giamberardino L, Guilbaud G: Behavioural pain-related disorders and contribution of the saphenous nerve in crush and chronic constriction injury of the rat sciatic nerve. Pain, 1994, 59, 301-312.
5. Bagdatoglu C, Saray A, Surucu HS, Ozturk H, Tamer L: Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. Neurosurgery, 2002, 51, 212-219, discussion 219-220.
6. Bennett G, Chung JM, Honore M, Seltzer Z: Models of neuropathic pain in the rat. Curr Protoc Neurosci, 2003, 9.14.01-19.14.16.
7. Bischofs S, Zelenka M, Sommer C: Evaluation of topiramate as an anti-hyperalgesic and neuroprotective agent in the peripheral nervous system. J Peripher Nerv Syst, 2004, 9, 70-78.
8. Bridges D, Thompson SW, Rice AS: Mechanisms of neuropathic pain. Br J Anaesth, 2001, 87, 12-26.
9. Dilsiz N, Sahaboglu A, Yildiz MZ, Reichenbach A: Protective effects of various antioxidants during ischemiareperfusion in the rat retina. Graefes Arch Clin Exp Ophthalmol, 2006, 244, 627-633.
10. Izumi Y, Kaji R: Clinical trials of ultra-high-dose methylcobalamin in ALS. Brain Nerve, 2007, 59, 1141-1147.
11. Kaji R, Kodama M, Imamura A, Hashida T, Kohara N, Ishizu M, Inui K, Kimura J: Effect of ultra high-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study. Muscle Nerve, 1998, 21, 1775-1778.
12. Kurtoglu Z, Ozturk AH, Bagdatoglu C, Turac A, Camdeviren H, Uzmansel D, Aktekin M: Effect of trapidil on the sciatic nerve with crush injury: a light microscopic study. Neuroanatomy, 2004, 3, 54-58.
13. Kurtoglu Z, Ozturk AH, Bagdatoglu C, Polat G, Aktekin M, Uzmansel D, Camdeviren H et al.: Effects of trapidil after crush injury in peripheral nerve. Acta Med Okayama, 2005, 59, 37-44.
14. Kuwabara S, Nakazawa R, Azuma N, Suzuki M, Miyajima K, Fukutake T, Hattori T: Intravenous methylcobalamin treatment for uremic and diabetic neuropathy in chronic hemodialysis patients. Intern Med, 1999, 38, 472-475.
15. Lundborg G, Dahlin LB: Anatomy, function, and pathophysiology of peripheral nerves and nerve compression. Hand Clin, 1996, 12, 185-193.
16. Lundborg G: Intraneural microcirculation. Orthop Clin North Am, 1988, 19, 1-12.
17. Mizisin A, Powell HC: Toxic neuropathies. Curr Opin Neurol, 1995, 8, 367-371.
18. Morani AS, Bodhankar SL: Neuroprotective effect of vitamin E acetate in models of mononeuropathy in rats. Neuroanatomy, 2008, 7, 33-37.
19. Muthal AP, Morani AS, Bodhankar SL: Neuroprotective effect of ultra-high dose of methylcobalamin in models of mononeuropathy in rats. Pharmacologyonline, 2008, 2, 282-295.
20. Pace A, Savarese A, Picardo M, Maresca V, Pacetti U, Del Monte G, Biroccio A et al: Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol, 2003, 21, 927-931.
21. Pfohl-Leszkowicz A, Keith G, Dirheimer G: Effect of cobalamin derivatives on in vitro enzymatic DNA methylation: methylcobalamin can act as a methyl donor. Biochemistry, 1991, 30, 8045-8051.
22. Ramteke VD, Tandan SK, Kumar D, Aruna Devi R, Shukla MK, Ravi Prakash V: Increased hyperalgesia by 5-nitro-2,3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats. Pharmacol Biochem Behav, 2009, 91, 417-422.
23. Silva M, Castro AA, Ramos EA, Peixoto E, Miranda F Jr, Pitta Gde B, Costa Rde F, Juliana Y: Histological and biochemical serum effects of alpha-tocopherol on ischemia/reperfusion-related injuries induced in the pelvic limb of rats. Acta Cir Bras, 2005, 20, 375-381.
24. Skalska S, Kyselova Z, Gajdosikova A, Karasu C, Stefek M, Stolc S: Protective effect of stobadine on NCV in streptozotocin-diabetic rats: augmentation by vitamin E. Gen Physiol Biophys, 2008, 27, 106-114.
25. Sun Y, Lai MS, Lu CJ: Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trials. Acta Neurol Taiwan, 2005, 14, 48-54.
26. Tahmoush A: Causalgia: redefinition as a clinical pain syndrome. Pain, 1981, 10, 187-197.
27. Tariq M, Arshaduddin M, Biary N, Al Deeb S, Al Moutaery K: Diethyldithiocarbamate (DEDC) impairs neuronal recovery following sciatic nerve injury in rats. Restor Neurol Neurosci, 2000, 17, 135-141.
28. Watanabe T, Kaji R, Oka N, Bara W, Kimura J: Ultrahigh dose methylcobalamin promotes nerve regeneration in experimental acrylamide neuropathy. J Neurol Sci, 1994, 122, 140-143.
29. Wieczorkiewicz-Płaza A, Płaza P, Maciejewski R, Czuczwar M, Przesmycki K: Effect of topiramate on mechanical allodynia in neuropathic pain model in rats. Pol J Pharmacol, 2004, 56, 275-278.
30. Yagihashi S, Tokui A, Kashiwamura H, Takagi S, Imamura K: In vivo effect of methylcobalamin on the peripheral nerve structure in streptozotocin diabetic rats. Horm Metab Res, 1982, 14, 10-13.
31. Zeng J, Dong KL, Li GC, Li LM: Effect of xiaokeling concentration fluid on mRNAexpression of insulin-like growth factor-1 in sciatic nerve of streptozotocin-induced diabetic rats. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2005, 30, 49-52.
32. Zimmermann M: Ethical considerations in relation to pain in animal experimentation. Acta Physiol Scand, 1986, 128, 221-233.
33. Zimmermann M: Pathobiology of neuropathic pain. Eur J Pharmacol, 2001, 429, 23-37.
34. Zochodne D, Ho LT: Endoneurial microenvironment and acute nerve crush injury in the rat sciatic nerve. Brain Res, 1990, 535, 43-48.