Possible neuroprotective effects of lecithin and α-tocopherol alone or in combination against ischemia/reperfusion insult in rat brain

Journal of Biochemical and Molecular Toxicology

Volumn 18, Issue 5, 2004, Pages 273-278

  Aabdallah, Dalaal M ^a   Eid, Nihad I ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Tocopherol; Global Ischemia Reperfusion; Lecithin; Oxidative Stress; Rat

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CATALASE; FREE RADICAL; GLUTATHIONE; LIPID PEROXIDE; MALONALDEHYDE; PHOSPHATIDYLCHOLINE; SUPEROXIDE DISMUTASE;

ADOLESCENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH ENERGY PHOSPHATE; MALE; NERVE CELL LESION; NONHUMAN; OXIDATION REDUCTION STATE; RAT; REPERFUSION INJURY;

ALPHA-TOCOPHEROL; ANIMALS; BRAIN; BRAIN ISCHEMIA; CATALASE; CEREBROVASCULAR CIRCULATION; MALE; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; REFERENCE VALUES; REPERFUSION INJURY; SOYBEANS; SUPEROXIDE DISMUTASE;

FELIS CATUS; RATTUS NORVEGICUS;

EID: 7744239458     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.20037     Document Type: Article

References (51)

1. Kempski OS. Neuroprotection. Models and basic principles. Anaesthesist 1994;43:S25-S33.
2. Wilson JX. Antioxidant defense of the brain: A role for astrocytes. Can J Physiol Pharmacol 1997;75:1149-1163.
3. Delbarre B, Delbarre G, Calinon F. Free radicals and neurotransmitters in gerbil brain. Influence of age and ischemia reperfusion insult. EXS 1992;62:199-212.
4. Smith CD, Carney JM, Tatsumo T, Stadtman ER, Floyd RA, Markesbery WR. Protein oxidation in aging brain. Ann NY Acad Sci 1992;663:110-119.
5. Dorrepaal CA, van Bel F, Moison RM, Shadid M, van de Bor M, Steendijk P, Berger HM. Oxidative stress during post-hypoxicischemic reperfusion in the newborn lamb: The effect of nitric oxide synthesis inhibition. Pediatr Res 1997;41:321-326.
6. Dargel R. Lipid peroxidation-A common pathogenic mechanism? Exp Toxicol Pathol 1992;44:169-181.
7. Rao AM, Hatcher JF, Dempsey RJ. CDP-choline: Neuroprotection in transient forebrain ischemia of gerbils. J Neurosci Res 1999;58:697-705.
8. 2+ antagonist drugs. In: Kriegelstein J, Oberpichler H, Editors. Pharmacology of cerebral ischemia. Schttutgart: Wissenschaftliche Verlagsgesellerschaft; 1990. pp. 311-315.
9. Holecek M, Mraz J, Koldova P, Skopec F. Effect of polyunsaturated phosphatidylcholine on liver degeneration onset after hepatectomy in the rat. Arzneimittelforschung 1992;42:337-339.
10. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Effect of bioactive tannoid principles of Emblica officinalis on ischemia-reperfusion-induced oxidative stress in rat heart. Phytomedicine 2002;9:171-174.
11. Uchiyama M, Mihara M. Determination of malondialdehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978;86:271-278.
12. Ahmed AE, Hussein GL, Loh J, Abdel-Rahman SZ. Studies on the mechanism of haloacetonitrile-induced gastrointestinal toxicity: Interaction of dibromoacetonitrile with glutathione and glutathione-S-transferase in rats. J Biochem Toxicol 1991;6:115-121.
13. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-474.
14. Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-126.
15. Siesjö BK. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. J Neurosurg 1992;77:169-184.
16. Seif-El-Nasr M, Mahran LG, El-Abhar HS, Khalifa AE, El-Denshary ESM. Possible neuroprotective effects of melatonin against ischaemia/reperfusion insult in rat brain. Med Sci Res 1999;27:605-608.
17. Wass CT, Lanier WL. Glucose modulation of ischemic brain injury: Review and clinical recommendations. Myo Clin Proc 1996;71:801-812.
18. Rehncrona S, Rosen I, Siesjö, BK. Brain lactic acid acidosis and ischemic cell damage. Part 1: Biochemistry and neurophysiology. J Cereb Blood Row Metab 1981;1:297-311.
19. Baud O, Greene AE, Li J, Wang H, Volpe JJ, Rosenberg PA. Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes. J Neurosci, 2004;24:1531-1540.
20. Chan PH, Chu L, Fishman RA. Reduction of activities of superoxide dismutase but not of glutathione peroxidase in rat brain regions following decapitation ischemia. Brain Res 1988;439:388-390.
21. El-Abhar HS, Shaalan M, Barakat M, El-Denshary EDS. Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats. J Pineal Res 2002;33:87-94.
22. Castillo J. Biochemistry of cerebral ischemia. Neurologia 1999;14:17-23.
23. Kinuta Y. Lipid peroxidation and changes in xanthine oxidase in cerebral ischemia. Nippon Geka Hokan 1989;8:59-70.
24. Gasull T, DeGregorio-Rocasolano N, Zapata A, Trullas R. Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation. J Biol Chem 2000;275:18350-18357.
25. Gasull T, DeGregorio-Rocasolano N, Trullas R. Overactivation of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and N-methyl-D-aspartate but not kainate receptors inhibits phosphatidylcholine synthesis before excitotoxic neuronal death. J Neurochem 2001;77:13-22.
26. Cui Z, Houweling M, Chen MH, Record M, Chap H, Vance DE, Terce F. A genetic defect in phosphatidylcholine biosynthesis triggers apoptosis in Chinese hamster ovary cells. J Biol Chem 1996;271:14668-14671.
27. Trovarelli G, De Medio GE, Porcellati S, Stramentinoli G, Porcellati G. The effect of S-adenosyl-L-methionine on ischemia-induced disturbances of brain phospholipid in the gerbil. Neurochem Res 1983;8:1597-1609.
28. Stoffel W, Darr W, Assmann G. Pleomorphic functions of highly unsaturated phospholipids in biological membranes and serum lipoproteins. Med Welt 1978;29:124-131.
29. Muma NA, Rowell PP. Brain and serum levels of choline and lecithin resulting from long-term administration. Neurochem Res 1986;11:481-488.
30. Muma NA, Rowell PP, Schultz GS. Effects of long-term dietary choline and phosphatidylcholine administration on muscarinic receptors in aged mouse brain. Neurol Res 1988;10:130-135.
31. Seidman MD, Khan MJ, Tang WX, Quirk WS. Influence of lecithin on mitochondrial DNA and age-related hearing loss. Otolaryngol Head Neck Surg 2002;127:138-144.
32. Chan PH, Fishman RA. The role of arachidonic acid in vasogenic brain edema. Fed Proc 1984;43:210-213.
33. Abe K, Kogure K, Yamamoto H, Imazawa M, Miyamoto K. Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex. J Neurochem 1987;48:503-509.
34. Hansen AJ. Effect of anoxia on ion distribution in the brain. Physiol Rev 1985;65:101-148.
35. Siesjö BK, Bengtsson F, Grampp W, Theander S. Calcium, excitotoxins, and neuronal death in the brain. Ann NY Acad Sci 1989;568:234-251.
36. Sato H, Hariyama H, Moriguchi K. S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat. Biochem Biophys Res Commun 1988;150:491-496.
37. Demirbilek S, Gurses I, Sezgin N, Karaman A, Gurbuz N. Protective effect of polyunsaturated phosphatidylcholine pretreatment on stress ulcer formation in rats. J Pediatr Surg 2004;39:57-62.
38. Olbrich K, Rawicz W, Needham D, Evans E. Water permeability and mechanical strength of polyunsaturated lipid bilayers. Biophys J 2000;79:321-327.
39. Suzuki J, Abiko H, Mizoi K, Oba M, Yoshimoto T. Protective effect of phenytoin and its enhanced action by combined administration with mannitol and vitamin E in cerebral ischemia. Acta Neurochir (Wien) 1987;88:56-64.
40. Yamamoto M, Shima T, Uozumi T, Sogabe T, Yamada K, Kawasaki T. A possible role of lipid peroxidation in cellular damages caused by cerebral ischemia and the protective effect of alpha-tocopherol administration. Stroke 1983;14:977-982.
41. Dzhandzhgava TG, Shakarishvili RR. Effect of alphatocopherol and selenium on the activity of antioxidant enzymes and level of lipid peroxidation products in erythrocytes of patients with cerebral ischemia. Vopr Med Khim 1991;37:79-82.
42. Villalobos MA, De La Cruz JP, Carrasco T, Smith-Agreda JM, Sanchez de la Cuesta F. Effects of alpha-tocopherol on lipid peroxidation and mitochondrial reduction of tetraphenyl tetrazolium in the rat brain. Brain Res Bull 1994;33:313-318.
43. Yoshida S, Busto R, Santiso M, Ginsberg MD. Brain lipid peroxidation induced by postischemic reoxygenation in vitro: Effect of vitamin E. J Cereb Blood Flow Metab 1984;4:466-469.
44. Wang X, Quinn PJ. Vitamin E and its function in membranes. Prog Lipid Res 1999;38:309-336.
45. Osakada F, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A. Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures. Eur J Pharmacol 2003;465:15-22.
46. Holgen NC, Waller SC, Sipes IG, Liebler DC. Reactions of peroxynitrite with gamma-tocopherol. Chem Res Toxicol 1997;10:401-407.
47. Tirosh O, Sen CK, Roy S, Packer L. Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death. Neuroscience 2000;97:531-541.
48. Behl C. Vitamin E protects neurons against oxidative cell death in vitro more effectively than 17-beta estradiol and induces the activity of the transcription factor NF-kappaB. J Neural Transm 2000;107:393-407.
49. Avrova NF, Shestak KI, Zakharova IO, Sokolova TV, Tyurina YY, Tyurin VA. The antioxidant prevention of disorders in calcium ion metabolism under the action of glutamate on the synaptosomes of the rat cerebral cortex. Ross Fiziol Zh Im I M Sechenova 1999;85:488-496.
50. Avrova NF, Shestak KI, Zakharova IO, Sokolova TV, Tyurina YY, Tyurin VA. The use of antioxidants to prevent glutamate-induced derangement of calcium ion metabolism in rat cerebral cortex synaptosomes. Neurosci Behav Physiol 2000;30:535-541.
51. Hurtado O, De Cristobal J, Sanchez V, Lizasoain I, Cardenas A, Pereira MP, Colado MI, Leza JC, Lorenzo P, Moro MA. Inhibition of glutamate release by delaying ATP fall accounts for neuroprotective effects of antioxidants in experimental stroke. FASEB J 2003;17:2082-2084.