Distribution of doxorubicin in rats undergoing ultrasonic drug delivery

Journal of Pharmaceutical Sciences

Volumn 99, Issue 7, 2010, Pages 3122-3131

  Staples, Bryant J ^a   Pitt, William G ^a   Roeder, Beverly L ^b   Husseini, Ghaleb A ^c   Rajeev, Deepthi ^b   Bruce Schaalje, G ^b  

^a Department of Electrical and Computer Engineering   (United States)

^b BRIGHAM YOUNG UNIVERSITY   (United States)

^c AMERICAN UNIVERSITY OF SHARJAH   (United Arab Emirates)

Author keywords

Doxorubicin; Drug delivery; Pharmacokinetics; Rat tumor model; Ultrasound

Indexed keywords

DOXORUBICIN; DRUG CARRIER; NANODELIV; POLOXAMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; HEART MUSCLE; LEG MUSCLE; LIVER; NONHUMAN; RAT; SKELETAL MUSCLE; TISSUE LEVEL; TUMOR GROWTH; ULTRASONIC DRUG DELIVERY; ULTRASOUND;

EID: 77953294901     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22088     Document Type: Article

References (43)

1. Hernot S, Klibanov AL. 2008. Microbubbles in ultrasound-triggered drug and gene delivery. Adv Drug Deliv Rev 60: 1153-1166.
2. Husseini GA, Pitt WG. 2008. Micelles and nanoparticles in ultrasonic drug and gene delivery. Adv Drug Deliv Rev 60: 1137-1152.
3. Wu JR, Nyborg WL. 2008. Ultrasound, cavitation bubbles and their interaction with cells. Adv Drug Deliv Rev 60:1103-1116.
4. Husseini GA, Diaz MA, Richardson ES, Christensen DA, Pitt WG. 2005. The role of cavitation in acoustically activated drug delivery. J Control Release 107:253-261. (Pubitemid 41316288)
5. Husseini GA, Myrup GD, Pitt WG, Christensen DA, Rapoport NY. 2000. Factors affecting acoustically-triggered release of drugs from polymeric micelles. J Control Release 69:43-52.
6. Guzman HR, Nguyen DX, Kahn S, Prausnitz MR. 2001. Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability. J Acoust Soc Am 110: 588-596. (Pubitemid 32642595)
7. Ogawa K, Tachibana K, Uchida T, Tai T, Yamashita N, Tsujita N, Miyauchi R. 2001. High-resolution scanning electron microscopic evaluation of cell-membrane porosity by ultrasound. Med Electron Microsc 34:249-253. (Pubitemid 34496210)
8. Prentice P, Cuschierp A, Dholakia K, Prausnitz M, Campbell P. 2005. Membrane disruption by optically controlled microbubble cavitation. Nat Phys 1:107-110.
9. Schlicher RK, Radhakrishna H, Tolentino TP, Apkarian RP, Zarnitsyn V, Prausnitz MR. 2006. Mechanism of intracellular delivery by acoustic cavitation. Ultrasound Med Biol 32:915-924. (Pubitemid 43903070)
10. Stringham SB, Viskovska MA, Richardson ES, Ohmine S, Husseini GA, Murray BK, Pitt WG. 2009. Over-pressure suppresses ultrasonic-induced drug uptake. Ultrasound Med Biol 35:409-415.
11. Tachibana K, Uchida T, Ogawa K, yamashita N, Tamura K. 1999. Induction of cell-membrane porosity by ultrasound. Lancet 353:1409.
12. Zhou Y, Kumon RE, Cui J, Deng CX. 2009. The size of sonoporation pores on the cell membrane. Ultrasound Med Biol 35:1756-1760.
13. Church CC. 2005. Frequency, pulse length, and the mechanical index. Acoust Res Lett Online 6:162-168.
14. Husseini GA, Diaz de la Rosa MA, Gabuji T, Zeng Y, Christensen DA, Pitt WG. 2007. Release of doxorubicin from unstabilized and stabilized micelles under the action of ultrasound. J Nanosci Nanotechnol 7:1-6.
15. Husseini GA, Christensen DA, Rapoport NY, Pitt WG. 2002. Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N-diethylacrylamide. J Control Release 83:302-304.
16. Marin A, Muniruzzaman M, Rapoport N. 2001. Acoustic activation of drug delivery from polymeric micelles: Effect of pulsed ultrasound. J Control Release 71:239-249. (Pubitemid 32276044)
17. Munshi N, Rapoport N, Pitt WG. 1997. Ultrasonic activated drug delivery from Pluronic P-105 micelles. Cancer Lett 117:1-7. (Pubitemid 27397219)
18. Pruitt JD, Pitt WG. 2002. Sequestration and ultrasound-induced release of doxorubicin from stabilized pluronic P105 micelles. Drug Deliv 9:253-258.
19. Nelson JL, Roeder BL, Carmen JC, Roloff F, Pitt WG. 2002. Ultrasonically activated chemotherapeutic drug delivery in a rat model. Cancer Res 62:7280-7283. (Pubitemid 36025250)
20. Rapoport N, Pitt WG, Sun H, Nelson JL. 2003. Drug delivery in polymeric micelles: From in vitro to in vivo. J Control Release 91:85-95. (Pubitemid 37288879)
21. Pruitt JD, Husseini G, Rapoport N, Pitt WG. 2000. Stabilization of Pluronic P-105 micelles with an interpenetrating network of N,N- diethylacrylamide. Macromolecules 33:9306-9309. (Pubitemid 32089777)
22. Staples BJ, Roeder BL, Husseini GA, Badamjav O, Schaalje GB, Pitt WG. 2009. Role of frequency and mechanical index in ultrasound-enhanced chemotherapy of tumors in rats. Cancer Chemother Pharmacol 64:593-600.
23. Danesi R, Fogli S, Gennari A, Conte P, Del Tacca M. 2002. Pharmacokinetic-pharmacodynamic relationships of the anthracycline anticancer drugs. Clin Pharmacokinet 41:431-444. (Pubitemid 34753680)
24. Linkesch W, Weger M, Eder I, Auner HW, Pernegg C, Kraule C, Czejka MJ. 2001. Long-term pharmacokinetics of doxorubicin HCl stealth liposomes in patients after polychemotheraphy with vinorelbine, cyclophosphamide and prednisone (CCVP). Eur J Drug Metab Pharmacokinet 26:179-184. (Pubitemid 32988559)
25. Tavoloni N, Guarino AM. 1980. Biliary and urinary excretion of adriamycin in anesthetized rats. Pharmacology 20:256-267. (Pubitemid 10100205)
26. Kabanov AV, Alakhov VY. 2002. Pluronic block copolymers in drug delivery: From micellar nanocontainers to biological response modifiers. Crit Rev Ther Drug Carrier Syst 19: 1-73.
27. http://www.bedfordlabs.com/products /ViewProductDetails? brand=Adriamycin.
28. Alakhov V, Klinski E, Li SM, Pietrzynski G, Venne A, Batrakova E, Bronitch T, Kabanov A. 1999. Block copolymer-based formulation of doxorubicin. From cell screen to clinical trials. Colloid Surf B 16:113-134.
29. Jewell RC, Khor SP, Kisor DF, LaCroix KAK, Wargin WA. 1997. Pharmacokinetics of RheothRx injection in healthy male volunteers. J Pharm Sci 86:808-812.
30. Jacquet P, Stuart OA, Dalton R, Chang D, Sugarbaker PH. 1996. Effect of intraperitoneal chemotherapy and fibrinolytic therapy on tumor implantation in wound sites. J Surg Oncol 62:128-134.
31. Martin F, Caignard A, Jeannin JF, Leclerc A, Martin M. 1983. Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors. Int J Cancer 32:623-627.
32. Alvarez-Cedron L, Sayalero ML, Lanao JM. 1999. High-performance liquid chromatographic validated assay of doxorubicin in rat plasma and tissues. J Chromatogr B 721: 271-278.
33. Rajeev D. 2007. Separate and Joint Anaysis of Longitudinal and Survival Data. M.S. Thesis, Brigham Young University, Provo, Utah, 89 pp.
34. Dreher MR, Liu WG, Michelich CR, Dewhirst MW, Yuan F, Chilkoti A. 2006. Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst 98:335-344.
35. Seymour LW. 1992. Passive tumor targeting of soluble macromolecules and drug conjugates. Crit Rev Ther Drug Carrier Syst 9:135-187.
36. Kruskal J, Miner B, Goldberg SN, Kane RA. 2002. Optimization of conventional clinical ultrasound parameters for enhancing drug delivery into tumors. Radiology 225:587-588.
37. Frenkel V, Etherington A, Greene M, Quijano J, Xie JW, Hunter F, Dromi S, Li KCP. 2006. Delivery of liposomal doxorubicin (Doxil) in a breast cancer tumor model: Investigation of potential enhancement by pulsed-high intensity focused ultrasound exposure. Acad Radiol 13:469-479.
38. Yuh EL, Shulman SG, Mehta SA, Xie JW, Chen LL, Frenkel V, Bednarski MD, Li KCP. 2005. Delivery of systemic chemotherapeutic agent to tumors by using focused ultrasound: Study in a murine model. Radiology 234:431-437.
39. Dromi S, Frenkel V, Luk A, Traughber B, Angstadt M, Bur M, Poff J, Xie JW, Libutti SK, Li KCP, Wood BJ. 2007. Pulsed-high intensity focused ultrasound and low temperature sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clin Cancer Res 13:2722-2727.
40. Husseini GA, Rapoport NY, Christensen DA, Pruitt JD, Pitt WG. 2002. Kinetics of ultrasonic release of doxorubicin from Pluronic P105 micelles. Coll Surf B: Biointerfaces 24:253-264.
41. Marin A, Muniruzzaman M, Rapoport N. 2001. Mechanism of the ultrasonic activation of micellar drug delivery. J Control Release 75:69-81.
42. Chen WS, Lu XC, Liu YB, Zhong P. 2004. The effect of surface agitation on ultrasound-mediated gene transfer in vitro. J Acoust Soc Am 116:2440-2450. (Pubitemid 39391646)
43. Mehier-Humbert S, Bettinger T, Yan F, Guy RH. 2005. Plasma membrane poration induced by ultrasound exposure: Implication for drug delivery. J Control Release 104:213-222.