Carbamate derivatives of betulinic acid and betulin with selective cytotoxic activity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 11, 2010, Pages 3409-3412

  Kommera, Harish ^a   Kaluderović, Goran N ^a   Dittrich, Sebastian ^a   Kalbitz, Jutta ^b   Dräger, Birgit ^a   Mueller, Thomas ^a   Paschke, Reinhard ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b BioSolutions Halle GmbH   (Germany)

Author keywords

Apoptosis; Betulin; Betulinic acid; Caspase activity; Cytotoxicity; Natural products

Indexed keywords

28 O ACETYLBETULIN; 3 O ETHYLCARBAMATE; 3 O ETHYLCARBAMATE OF 28 O ACETYLBETULIN; ANTINEOPLASTIC AGENT; BETULIC ACID; BETULIN; BIS(ETHYLCARBAMATE)BETULIN; CARBAMIC ACID DERIVATIVE; CASPASE 3; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; COLON CANCER; COLORIMETRY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; LUNG CANCER; TUMOR CELL LINE;

CARBAMATES; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; TRITERPENES;

EID: 77953291236     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.004     Document Type: Article

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