Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 16, 2009, Pages 4814-4817

  Drag Zalesinska, Malgorzata ^a   Kulbacka, Julita ^a   Saczko, Jolanta ^a   Wysocka, Teresa ^a   Zabel, Maciej ^a,b   Surowiak, Pawel ^a,c   Drag, Marcin ^d  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^c Dolnoslaskie Centrum Onkologii Wroclaw   (Poland)

^d WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Apoptosis; Betulin; Betulinic acid; Cytotoxicity

Indexed keywords

AMINO ACID DERIVATIVE; BETULIC ACID; BETULIN; ESTER DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ANALYSIS;

AMINO ACIDS; ANTINEOPLASTIC AGENTS; ESTERS; HUMANS; SOLUBILITY; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 67651100837     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.046     Document Type: Article

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