The effects of salvianolic acid B from Radix Salvia miltiorrhizae on the oral pharmacokinetics of metoprolol and metoprolol acid in rats

Phytotherapy Research

Volumn 24, Issue 6, 2010, Pages 846-851

  Wan, Ren Zhong ^a,b   Zhou, Mao Jin ^b   Liu, Chang Xiao ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Metoprolol; Metoprolol acid; Pharmacokinetics; Radix Salvia miltiorrhizae; Salvianolic acid B

Indexed keywords

DRUG METABOLITE; METOPROLOL; METOPROLOL ACID; SALVIANOLIC ACID B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; HERB DRUG INTERACTION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; METABOLIC RATE; NONHUMAN; RAT; SALVIA MILTIORRHIZA; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; AREA UNDER CURVE; BENZOFURANS; FEMALE; MALE; METOPROLOL; RATS; RATS, WISTAR; SALVIA MILTIORRHIZA;

RATTUS; SALVIA MILTIORRHIZA;

EID: 77953248890     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3030     Document Type: Article

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