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Volumn 197, Issue , 2010, Pages 251-266

Mucoadhesive drug delivery systems

Author keywords

Mucoadhesion; Mucoadhesion tests; Mucoadhesive delivery systems; Mucoadhesive polymers; Mucus

Indexed keywords

ADHESIVE AGENT; ALGINIC ACID; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; CARBOMER; CARBON; CARBOXYMETHYLCELLULOSE; CELLULOSE DERIVATIVE; CHITOSAN; CORTICOSTEROID DERIVATIVE; ESTROGEN DERIVATIVE; FLURBIPROFEN; FUROSEMIDE; HYALURONIC ACID; HYDROGEN; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; LOCAL ANESTHETIC AGENT; MACROGOL; NANOPARTICLE; POLYACRYLIC ACID; POLYCARBOPHIL; POLYLYSINE; POLYMER; POLYVINYL ALCOHOL; POVIDONE; UNINDEXED DRUG; DRUG; DRUG CARRIER;

EID: 77953244655     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-00477-3_9     Document Type: Review
Times cited : (55)

References (42)
  • 2
    • 0031890348 scopus 로고    scopus 로고
    • Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites
    • Akiyama Y, Nagahara N, Nara E, Kitano M, Iwasa S, Yamamoto I, Azuma J, Ogawa Y (1998) Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites. J Pharm Pharmacol 50:159-166
    • (1998) J Pharm Pharmacol , vol.50 , pp. 159-166
    • Akiyama, Y.1    Nagahara, N.2    Nara, E.3    Kitano, M.4    Iwasa, S.5    Yamamoto, I.6    Azuma, J.7    Ogawa, Y.8
  • 3
    • 0025330914 scopus 로고
    • The adherent gastric mucus gel barrier in man and changes in peptic ulceration
    • Allen A, Cunliffe WJ, Pearson JP, Venables CW (1990) The adherent gastric mucus gel barrier in man and changes in peptic ulceration. J Intern Med 228:83-90
    • (1990) J Intern Med , vol.228 , pp. 83-90
    • Allen, A.1    Cunliffe, W.J.2    Pearson, J.P.3    Venables, C.W.4
  • 5
    • 0037151422 scopus 로고    scopus 로고
    • Quantification of the bioadhesive properties of protein-coated PVM/MA nanoparticles
    • Arbos P, Arangoa MA, Campanero MA, Irache JM (2002) Quantification of the bioadhesive properties of protein-coated PVM/MA nanoparticles. Int J Pharm 242:129-136
    • (2002) Int J Pharm , vol.242 , pp. 129-136
    • Arbos, P.1    Arangoa, M.A.2    Campanero, M.A.3    Irache, J.M.4
  • 6
    • 0028071051 scopus 로고
    • Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2
    • Artursson P, Lindmark T, Davis SS, Illum L (1994) Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm Res 11:1358-1361
    • (1994) Pharm Res , vol.11 , pp. 1358-1361
    • Artursson, P.1    Lindmark, T.2    Davis, S.S.3    Illum, L.4
  • 8
    • 0033020555 scopus 로고    scopus 로고
    • Polymers with thiol groups: A new generation of mucoadhesive polymers?
    • Bernkop-Schnürch A, Schwarz V, Steininger S (1999) Polymers with thiol groups: a new generation of mucoadhesive polymers? Pharm Res 16:876-881
    • (1999) Pharm Res , vol.16 , pp. 876-881
    • Bernkop-Schnürch, A.1    Schwarz, V.2    Steininger, S.3
  • 9
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery II: Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers
    • Ch'ng HS, Park H, Kelly P, Robinson JR (1985) Bioadhesive polymers as platforms for oral controlled drug delivery II: Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers. J Pharm Sci 74:399-405
    • (1985) J Pharm Sci , vol.74 , pp. 399-405
    • Ch'Ng, H.S.1    Park, H.2    Kelly, P.3    Robinson, J.R.4
  • 10
    • 0023892746 scopus 로고
    • Pharmaceutical and medical aspects of bioadhesive systems for drug administration
    • Duchene D, Touchard F, Peppas NA (1988) Pharmaceutical and medical aspects of bioadhesive systems for drug administration. Drug Dev Ind Pharm 14:283-318
    • (1988) Drug Dev Ind Pharm , vol.14 , pp. 283-318
    • Duchene, D.1    Touchard, F.2    Peppas, N.A.3
  • 11
    • 0035997333 scopus 로고    scopus 로고
    • Nasal delivery of insulin using novel chitosan based formulations: A comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles
    • Dyer AM, Hinchcliffe M, Watts P, Castile J, Jabbal-Gill I, Nankervis R, Smith A, Illum L (2002) Nasal delivery of insulin using novel chitosan based formulations: a comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles. Pharm Res 19:998-1008
    • (2002) Pharm Res , vol.19 , pp. 998-1008
    • Dyer, A.M.1    Hinchcliffe, M.2    Watts, P.3    Castile, J.4    Jabbal-Gill, I.5    Nankervis, R.6    Smith, A.7    Illum, L.8
  • 12
    • 0017862114 scopus 로고
    • Intestinal mucins in health and disease
    • Forstner JF (1978) Intestinal mucins in health and disease. Digestion 17:234-263
    • (1978) Digestion , vol.17 , pp. 234-263
    • Forstner, J.F.1
  • 13
    • 26644434123 scopus 로고    scopus 로고
    • Comparison of the mucoadhesive properties of various polymers
    • Grabovac V, Guggi D, Bernkop-Schnürch A (2005) Comparison of the mucoadhesive properties of various polymers. Adv Drug Deliv Rev 57:1713-1723
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1713-1723
    • Grabovac, V.1    Guggi, D.2    Bernkop-Schnürch, A.3
  • 14
    • 0023917757 scopus 로고
    • Binding of acrylic polymers to mucin/epithelial surfaces: Structure property relationship
    • Gu JM, Robinson JR, Leung SHS (1988) Binding of acrylic polymers to mucin/epithelial surfaces: structure property relationship. Crit Rev Ther Drug Carr Syst 5:21-67
    • (1988) Crit Rev Ther Drug Carr Syst , vol.5 , pp. 21-67
    • Gu, J.M.1    Robinson, J.R.2    Leung, S.H.S.3
  • 15
    • 0025320595 scopus 로고
    • GI transit of potential bioadhesive formulations in man: A scintigraphic study
    • Harris D, Fell JT, Sharma HL, Taylor DC (1990) GI transit of potential bioadhesive formulations in man: a scintigraphic study. J Control Release 12:45-53
    • (1990) J Control Release , vol.12 , pp. 45-53
    • Harris, D.1    Fell, J.T.2    Sharma, H.L.3    Taylor, D.C.4
  • 16
    • 0025108791 scopus 로고
    • A simple rheological method for the in vitro assessment of mucinpolymer bioadhesive bond strength
    • Hassan EE, Gallo JM (1990) A simple rheological method for the in vitro assessment of mucinpolymer bioadhesive bond strength. Pharm Res 7:491-495
    • (1990) Pharm Res , vol.7 , pp. 491-495
    • Hassan, E.E.1    Gallo, J.M.2
  • 17
    • 0028145909 scopus 로고
    • In-vivo evaluation of a bioadhesive containing indomethacin tablets
    • Hosny EA, Al-Meshal MA (1994) In-vivo evaluation of a bioadhesive containing indomethacin tablets. Drug Dev Ind Pharm 20:2715-2720
    • (1994) Drug Dev Ind Pharm , vol.20 , pp. 2715-2720
    • Hosny, E.A.1    Al-Meshal, M.A.2
  • 18
    • 0027321167 scopus 로고
    • Evidence of mucoadhesion by chain interpenetration at a poly(acrylic acid)/mucin interface using ATR-FTIR spectroscopy
    • Jabbari E, Wisniewski N, Peppas NA (1993) Evidence of mucoadhesion by chain interpenetration at a poly(acrylic acid)/mucin interface using ATR-FTIR spectroscopy. J Control Release 26:99-108
    • (1993) J Control Release , vol.26 , pp. 99-108
    • Jabbari, E.1    Wisniewski, N.2    Peppas, N.A.3
  • 20
    • 0023119830 scopus 로고
    • The effect of polycarbophil on the gastric emptying of pellets
    • Khosla L, Davis SS (1987) The effect of polycarbophil on the gastric emptying of pellets. J Pharm Pharmacol 39:47-49
    • (1987) J Pharm Pharmacol , vol.39 , pp. 47-49
    • Khosla, L.1    Davis, S.S.2
  • 21
    • 0022852854 scopus 로고
    • Topical ocular drug delivery: Recent developments and future challenges
    • Lee VHL, Robinson JR (1986) Topical ocular drug delivery: recent developments and future challenges. J Ocular Pharmacol 2:67-108
    • (1986) J Ocular Pharmacol , vol.2 , pp. 67-108
    • Lee, V.H.L.1    Robinson, J.R.2
  • 22
    • 0030453145 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo
    • Lueßen HL, de Leeuw BJ, Langemeyer MW, de Boer AG, Verhoef JC, Junginger HE (1996) Mucoadhesive polymers in peroral peptide drug delivery VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo. Pharm Res 13:1668-1672
    • (1996) Pharm Res , vol.13 , pp. 1668-1672
    • Lueßen, H.L.1    De Leeuw, B.J.2    Langemeyer, M.W.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 24
    • 0031018133 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide delivery IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro
    • Lueßen HL, Rentel CO, Kotzé AF, Lehr CM, de Boer AG, Verhoef JC, Junginger HE (1997) Mucoadhesive polymers in peroral peptide delivery IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro. J Control Release 45:15-23
    • (1997) J Control Release , vol.45 , pp. 15-23
    • Lueßen, H.L.1    Rentel, C.O.2    Kotzé, A.F.3    Lehr, C.M.4    De Boer, A.G.5    Verhoef, J.C.6    Junginger, H.E.7
  • 25
  • 26
    • 0002611505 scopus 로고
    • Ocular pharmacokinetics
    • Sears MC (ed) Springer, Berlin
    • Maurice DM, Mishima S (1984) Ocular pharmacokinetics. In: Sears MC (ed) Pharmacology of the eye. Springer, Berlin, pp 19-116
    • (1984) Pharmacology of the Eye , pp. 19-116
    • Maurice, D.M.1    Mishima, S.2
  • 27
    • 0026599377 scopus 로고
    • Development and evaluation of flurbiprofen hydrogels on the breakdown of the blood/aqueous humor barrier
    • Mengi S, Deshpande SG (1992) Development and evaluation of flurbiprofen hydrogels on the breakdown of the blood/aqueous humor barrier. STP Pharma 2:118-124
    • (1992) STP Pharma , vol.2 , pp. 118-124
    • Mengi, S.1    Deshpande, S.G.2
  • 28
    • 77953654907 scopus 로고
    • An in-vitro evaluation of mucosa-adhesion using tensile and shear stresses
    • Mortazawi SA, Smart JD (1993) An in-vitro evaluation of mucosa-adhesion using tensile and shear stresses. J Pharm Pharmacol 45(suppl.):1108
    • (1993) J Pharm Pharmacol , vol.45 , Issue.SUPPL.
    • Mortazawi, S.A.1    Smart, J.D.2
  • 29
    • 26844567547 scopus 로고
    • Rectal and vaginal absorption of peptides and proteins
    • Muranishi S, Yamamoto A, Okada H (1993) Rectal and vaginal absorption of peptides and proteins. Pharm Biotech 4:199-227
    • (1993) Pharm Biotech , vol.4 , pp. 199-227
    • Muranishi, S.1    Yamamoto, A.2    Okada, H.3
  • 30
    • 0022368327 scopus 로고
    • Physico-chemical properties of water insoluble polymers important to mucin/epithelial adhesion
    • Park H, Robinson JR (1985) Physico-chemical properties of water insoluble polymers important to mucin/epithelial adhesion. J Control Release 2:47-57
    • (1985) J Control Release , vol.2 , pp. 47-57
    • Park, H.1    Robinson, J.R.2
  • 31
    • 0242525615 scopus 로고    scopus 로고
    • Oxprenolol-loaded bioadhesive microspheres: Preparation and in vitro/in vivo characterization
    • Preda M, Leucuta SE (2003) Oxprenolol-loaded bioadhesive microspheres: preparation and in vitro/in vivo characterization. J Microencapsul 20:777-789
    • (2003) J Microencapsul , vol.20 , pp. 777-789
    • Preda, M.1    Leucuta, S.E.2
  • 32
    • 0017610710 scopus 로고
    • The upper airways: I. Nasal physiology and defence of the lungs
    • Proctor DF (1977) The upper airways: I. Nasal physiology and defence of the lungs. Am Rev Respir Disord 115:97-129
    • (1977) Am Rev Respir Disord , vol.115 , pp. 97-129
    • Proctor, D.F.1
  • 33
    • 0024352077 scopus 로고
    • A novel in situ method to test polymers and coated microparticles for bioadhesion
    • Rango Rao KV, Buri P (1989) A novel in situ method to test polymers and coated microparticles for bioadhesion. Int J Pharm 52:265-270
    • (1989) Int J Pharm , vol.52 , pp. 265-270
    • Rango Rao, K.V.1    Buri, P.2
  • 34
    • 0028314775 scopus 로고
    • Vaginal and reproductive system treatment using a bioadhesive polymer
    • Robinson JR, Bologna WJ (1994) Vaginal and reproductive system treatment using a bioadhesive polymer. J Control Release 28:87-94
    • (1994) J Control Release , vol.28 , pp. 87-94
    • Robinson, J.R.1    Bologna, W.J.2
  • 35
    • 26644454810 scopus 로고    scopus 로고
    • The basics and underlying mechanisms of mucoadhesion
    • Smart SD (2005) The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev 57:1556-1568
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1556-1568
    • Smart, S.D.1
  • 36
    • 0015965195 scopus 로고
    • Electron microscopy, carbohydrate analysis and biological activities of the proteins absorbed in two hours to tooth surfaces in vivo
    • Sonju T, Cristensen TB, Kornstad L, Rolla G (1974) Electron microscopy, carbohydrate analysis and biological activities of the proteins absorbed in two hours to tooth surfaces in vivo. Caries Res 8:113-122
    • (1974) Caries Res , vol.8 , pp. 113-122
    • Sonju, T.1    Cristensen, T.B.2    Kornstad, L.3    Rolla, G.4
  • 37
    • 26644447977 scopus 로고    scopus 로고
    • Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems
    • Takeuchi H, Thongborisute J, Matsui Y, Sugihara H, Yamamoto H, Kawashima Y (2005) Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems. Adv Drug Deliv Rev 57:1583-1594
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1583-1594
    • Takeuchi, H.1    Thongborisute, J.2    Matsui, Y.3    Sugihara, H.4    Yamamoto, H.5    Kawashima, Y.6
  • 38
    • 26644434124 scopus 로고    scopus 로고
    • Nasal mucoadhesive drug delivery: Background, applications, trends and future perspectives
    • Ugwoke MI, Agu RU, Verbeke N, Kinget R (2005) Nasal mucoadhesive drug delivery: background, applications, trends and future perspectives. Adv Drug Deliv Rev 57:1640-1665
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1640-1665
    • Ugwoke, M.I.1    Agu, R.U.2    Verbeke, N.3    Kinget, R.4
  • 39
    • 0031745232 scopus 로고    scopus 로고
    • Chitosan-EDTA Conjugate: A novel polymer for topical used gels
    • Valenta C, Christen B, Bernkop-Schnürch A (1998) Chitosan-EDTA Conjugate: a novel polymer for topical used gels. J Pharm Pharmacol 50:445-452
    • (1998) J Pharm Pharmacol , vol.50 , pp. 445-452
    • Valenta, C.1    Christen, B.2    Bernkop-Schnürch, A.3
  • 41
    • 0034306493 scopus 로고    scopus 로고
    • The scope and potential of vaginal drug delivery
    • Vermani K, Garg S (2000) The scope and potential of vaginal drug delivery. Pharm Sci Technol Today 3:359-364
    • (2000) Pharm Sci Technol Today , vol.3 , pp. 359-364
    • Vermani, K.1    Garg, S.2
  • 42
    • 0004023403 scopus 로고
    • Formation of adhesive bond
    • Marcel Dekker Inc, New York
    • Wu S (1982) Formation of adhesive bond. Polymer interface and adhesion. Marcel Dekker Inc, New York, pp 359-447
    • (1982) Polymer Interface and Adhesion , pp. 359-447
    • Wu, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.