Hypertrophic cardiomyopathy-linked mutation d145e drastically alters calcium binding by the C-domain of cardiac troponin C

Biochemistry

Volumn 49, Issue 23, 2010, Pages 4813-4820

  Swindle, Nicholas ^a   Tikunova, Svetlana B ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BINDING PROPERTIES; C-DOMAIN; CALCIUM BINDING; CALCIUM BINDING PROPERTIES; CALCIUM CONCENTRATION; CARDIAC TROPONIN; CARDIAC TROPONIN C; CARDIAC TROPONIN I; COOPERATIVE INTERACTIONS; HYDROPHOBIC PROBES; HYPERTROPHIC CARDIOMYOPATHY; REGULATORY FUNCTIONS; REGULATORY REGIONS;

BINDING ENERGY; CALCIUM; HEART; HYDROPHOBICITY; MAGNESIUM;

BINDING SITES;

CALCIUM; MAGNESIUM; TROPONIN C;

A8V GENE; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; D145E GENE; E134D GENE; ENZYME ACTIVE SITE; FLUORESCENCE ANALYSIS; GENE; GENE MUTATION; HUMAN; HYDROPHOBICITY; HYPERTROPHIC CARDIOMYOPATHY; PRIORITY JOURNAL; PROTEIN INTERACTION;

AMINO ACID SUBSTITUTION; ASPARTIC ACID; CALCIUM; CALCIUM SIGNALING; CARDIOMYOPATHY, HYPERTROPHIC; GLUTAMIC ACID; HUMANS; MAGNESIUM; MUSCLE CONTRACTION; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TROPONIN C;

EID: 77953240679     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100400h     Document Type: Article

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