Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems

Biochemistry

Volumn 49, Issue 9, 2010, Pages 1975-1984

  Tikunova, Svetlana B ^a   Liu, Bin ^a,b   Swindle, Nicholas ^a   Little, Sean C ^b   Gomes, Aldrin V ^c   Swartz, Darl R ^d   Davis, Jonathan P ^b  

^a UNIVERSITY OF HOUSTON   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-ASE ACTIVITY; BIOCHEMICAL SYSTEMS; CALCIUM BINDING; CARDIAC MUSCLES; HYDROPHOBIC RESIDUES; INTERMOLECULAR INTERACTIONS; INTRINSIC PROPERTY; REGULATORY DOMAIN; SIDE CHAINS; THIN FILAMENTS; TROPONIN; TROPONIN C;

CALCIUM; COMPLEXATION; FILAMENTS (LAMP); HYDROPHOBICITY; LAWS AND LEGISLATION; PROTEINS;

CALCIUM ALLOYS;

CALCIUM; CONTRACTILE PROTEIN; LEUCINE; METHIONINE; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN SUBFRAGMENT 1; PHENYLALANINE; TROPONIN C; VALINE;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; HEART CONTRACTION; HYDROPHOBICITY; MOLECULAR INTERACTION; MUTATION; MYOFILAMENT; PRIORITY JOURNAL; PROTEIN DOMAIN; THIN FILAMENT;

AMINO ACID SEQUENCE; CALCIUM; CONTRACTILE PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; TROPONIN C; TROPONIN I; TROPONIN T;

EID: 77749286325     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901867s     Document Type: Article

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