Ca2+ and Mg2+ binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament

International Journal of Biochemistry and Cell Biology

Volumn 38, Issue 1, 2006, Pages 110-122

  Braga, Carolina A C A ^a   Pinto, José Renato ^a   Valente, Ana Paula ^a   Silva, Jerson L ^a   Sorenson, Martha M ^a   Foguel, Débora ^a   Suarez, Marisa C ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

bis ANS; Divalent cations; F154W C domain; Troponin C; Tryptophan fluorescence

Indexed keywords

CALCIUM; MAGNESIUM; PHENYLALANINE; PROTEIN SUBUNIT; SULFONIC ACID DERIVATIVE; TROPONIN C;

AFFINITY CHROMATOGRAPHY; ANIMAL TISSUE; ARTICLE; ARTIFACT; BINDING SITE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONFORMATION; CONTROLLED STUDY; DISSOCIATION; FLUORESCENCE; HYDROPHOBICITY; IONIC STRENGTH; NONHUMAN; PROTEIN AGGREGATION; PROTEIN DOMAIN; RABBIT; THIN FILAMENT;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CALCIUM; CHICKENS; HYDROPHOBICITY; MAGNESIUM; MULTIPROTEIN COMPLEXES; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; TROPONIN C;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 27544511447     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2005.08.009     Document Type: Article

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