Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule

Molecular and Cellular Neuroscience

Volumn 44, Issue 3, 2010, Pages 246-259

  Gebhart, Mathias ^a   Juhasz Vedres, Gabriella ^a   Zuccotti, Annalisa ^b   Brandt, Niels ^c   Engel, Jutta ^c   Trockenbacher, Alexander ^a   Kaur, Gurjot ^a   Obermair, Gerald J ^d   Knipper, Marlies ^b   Koschak, Alexandra ^a   Striessnig, Jörg ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Calcium channels; Calcium current inactivation; Channel gating; Hearing; Inner hair cells

Indexed keywords

BINDING PROTEIN; CALCIUM CHANNEL L TYPE; CALCIUM ION; MESSENGER RNA; NEUROTRANSMITTER; RAB PROTEIN; RAB3 INTERACTION MOLECULE; RAB3 INTERACTION MOLECULE 2ALPHA; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; ALPHA1D (CAV1.3) L TYPE CALCIUM CHANNEL, HUMAN; ALPHA1D (CAV1.3) L-TYPE CALCIUM CHANNEL, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; ISOPROTEIN; NERVE PROTEIN; RIMS1 PROTEIN, HUMAN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; CONTROLLED STUDY; FETUS; HAIR CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR MECHANICS; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROTRANSMITTER RELEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; ALTERNATIVE RNA SPLICING; ANIMAL; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; PATCH CLAMP; PHYSIOLOGY; TWO HYBRID SYSTEM;

ACTION POTENTIALS; ALTERNATIVE SPLICING; ANIMALS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; GTP-BINDING PROTEINS; HAIR CELLS, AUDITORY, INNER; HUMANS; ION CHANNEL GATING; MICE; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN ISOFORMS; RAB3 GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 77953231923     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2010.03.011     Document Type: Article

References (66)

1. v1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. J. Neurosci. 2005, 25:11577-11585.
2. 2+ channel signaling complexes in neurons. J. Neurochem. 2008, 105:573-583.
3. Catterall W.A., Perez-Reyes E., Snutch T.P., Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol. Rev. 2005, 57:411-425.
4. 2+ channel beta subunits revealed by their expression in adult rat heart cells. J. Physiol. 2002, 541:435-452.
5. v1.3 channels in mouse auditory hair cells. J. Physiol. 2007, 585:791-803.
6. Dai S., Hall D.D., Hell J.W. Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol. Rev. 2009, 89:411-452.
7. 2 subunits of voltage-gated calcium channels. Trends Pharmacol. Sci. 2007, 28:220-228.
8. Dolphin A.C. Beta subunits of voltage-gated calcium channels. J. Bioenerg. Biomembr. 2003, 35:599-620.
9. Findeisen F., Minor D.L. Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation. J. Gen. Physiol. 2009, 133:327-343.
10. V1.2 encodes a transcription factor. Cell 2006, 127:591-606.
11. 2+ channels expressed in dysgenic myotubes. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:1903-1908.
12. Grant L., Fuchs P. Calcium- and calmodulin-dependent inactivation of calcium channels in inner hair cells of the rat cochlea. J. Neurophysiol. 2008, 99:2183-2193.
13. 2+-channel β4 subunit. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:307-312.
14. 2+ dependence of vesicle fusion at auditory ribbon synapses. Nat. Neurosci. 2010, 13:45-52.
15. v1.3 calcium channels in gerbil inner hair cells. J. Physiol. 2008, 586:1029-1042.
16. 2+ dependence of exocytosis during development of mouse inner hair cells. J. Physiol. 2005, 563:177-191.
17. 2+ channels. Nat. Neurosci. 2007, 10:691-701.
18. 2+ channels of the embryonic mouse heart. Eur. J. Pharmacol. 2002, 447:279-284.
19. Knipper M., Zinn C., Maier H., Praetorius M., Rohbock K., Kopschall I., Zimmermann U. Thyroid hormone deficiency before the onset of hearing causes irreversible damage to peripheral and central auditory systems. J. Neurophysiol. 2000, 83:3101-3112.
20. 2+ channels in mature outer hair cells supports outer hair cell afferent signaling. J. Neurosci. 2007, 27:6442-6451.
21. Kong J.H., Adelman J.P., Fuchs P.A. Expression of the SK2 calcium-activated potassium channel is required for cholinergic function in mouse cochlear hair cells. J. Physiol. 2008, 586:5471-5485.
22. 2+ channels activating at negative voltages. J. Biol. Chem. 2001, 276:22100-22106.
23. Kros C.J., Ruppersberg J.P., Rusch A. Expression of a potassium current in inner hair cells during development of hearing in mice. Nature 1998, 394:281-284.
24. 2+ channel subunits beta3 or beta4. Channels (Austin) 2009, 3.
25. Lee S., Briklin O., Hiel H., Fuchs P. Calcium-dependent inactivation of calcium channels in cochlear hair cells of the chicken. J. Physiol. 2007, 583:909-922.
26. Leroy J., Richards M.W., Butcher A.J., Nieto-Rostro M., Pratt W.S., Davies A., Dolphin A.C. Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties. J. Neurosci. 2005, 25:6984-6996.
27. Liang F., Zhang B., Tang J., Guo J., Li W., Ling E.A., Chu H., Wu Y., Chan Y.G., Cao Q. RIM3 is a postsynaptic protein in the rat central nervous system. J. Comp. Neurol. 2007, 503:501-510.
28. Lipscombe D., Raingo J. Alternative splicing matters: N-type calcium channels in nociceptors. Channels (Austin) 2007, 1:225-227.
29. Long J.Z., Lackan C.S., Hadjantonakis A.K. Genetic and spectrally distinct in vivo imaging: embryonic stem cells and mice with widespread expression of a monomeric red fluorescent protein. BMC Biotechnol. 2005, 5:20.
30. 2+ channels in cardiac pacemaker activity. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:5543-5548.
31. Marcotti W., Johnson S.L., Rusch A., Kros C.J. Sodium and calcium currents shape action potentials in immature mouse inner hair cells. J. Physiol. 2003, 552:743-761.
32. 2+ conductances in hair cells. Hear. Res. 2004, 195:67-74.
33. McRory J.E., Hamid J., Doering C.J., Garcia E., Parker R., Hamming K., Chen L., Hildebrand M., Beedle A.M., Feldcamp L., Zamponi G.W., Snutch T.P. The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. J. Neurosci. 2004, 24:1707-1718.
34. 2+ currents in neonatal outer hair cells of mice. J. Physiol. 2003, 553:747-758.
35. Moody W.J., Bosma M.M. Ion channel development, spontaneous activity, and activity-dependent development in nerve and muscle cells. Physiol. Rev. 2005, 85:883-941.
36. 2+ channel abundance and function in inner hair cells and is required for hearing. J. Neurosci. 2009, 29:10730-10740.
37. V1.2) to synaptic and extrasynaptic compartments in hippocampal neurons. Eur. J. NeuroSci. 2004, 19:2109-2122.
38. Obermair G.J., Schlick B., Di Biase V., Subramanyam P., Gebhart M., Baumgartner S., Flucher B.E. Reciprocal interactions regulate targeting of calcium channel β subunits and membrane expression of α1 subunits in cultured hippocampal neurons. J. Biol. Chem. 2010, 285:5776-5791.
39. Opatowsky Y., Chen C.C., Campbell K.P., Hirsch J.A. Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the α1 interaction domain. Neuron 2004, 42:387-399.
40. 2+ channels. Cell 2000, 102:89-97.
41. Pragnell M., De Waard M., Mori Y., Tanabe T., Snutch T.P., Campbell K.P. Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the α1-subunit. Nature 1994, 368:67-70.
42. Rabl K., Thoreson W.B. Calcium-dependent inactivation and depletion of synaptic cleft calcium ions combine to regulate rod calcium currents under physiological conditions. Eur. J. NeuroSci. 2002, 16:2070-2077.
43. Regus-Leidig H., Tom Dieck S., Specht D., Meyer L., Brandstatter J.H. Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres. J. Comp. Neurol. 2009, 512:814-824.
44. Schlick B., Flucher B., Obermair G.J. Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons. Neuroscience. 2010, 167:786-798.
45. Schnee M.E., Ricci A.J. Biophysical and pharmacological characterization of voltage-gated calcium currents in turtle auditory hair cells. J. Physiol. 2003, 549:697-717.
46. 2+-triggered neurotransmitter release. EMBO J. 2006, 25:5852-5863.
47. 2+-dependent inactivation within auditory hair cells. J. Neurosci. 2006, 26:10690-10699.
48. v1.3L-type calcium channels by alternative splicing of a C-terminal regulatory domain. J. Biol. Chem. 2008, 283:20733-20744.
49. 2+ channels. Nat. Neurosci. 2006, 9:1108-1116.
50. Sobkowicz H.M., Rose J.E., Scott G.E., Slapnick S.M. Ribbon synapses in the developing intact and cultured organ of Corti in the mouse. J. Neurosci. 1982, 2:942-957.
51. 2+ current properties. J. Neurophysiol. 2003, 89:1143-1149.
52. Striessnig J. C-terminal tailoring of L-type calcium channel function. J. Physiol. 2007, 585:643-644.
53. Subramanyam P., Obermair G.J., Baumgartner S., Gebhart M., Striessnig J., Kaufmann W.A., Geley S., Flucher B.E. Activity and calcium regulate nuclear targeting of the calcium channel β4b subunit in nerve and muscle cells. Channels (Austin) 2009, 3.
54. Sudhof T.C. The synaptic vesicle cycle. Annu. Rev. Neurosci. 2004, 27:509-547.
55. 2+ channels. J. Gen. Physiol. 2005, 126:365-377.
56. 2+ currents in neonatal mouse inner hair cells. Eur. J. Pharmacol. 2007, 573:39-48.
57. tom Dieck S., Altrock W.D., Kessels M.M., Qualmann B., Regus H., Brauner D., Fejtova A., Bracko O., Gundelfinger E.D., Brandstatter J.H. Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. J. Cell. Biol. 2005, 168:825-836.
58. Vitko I., Shcheglovitov A., Baumgart J.P., Arias O., Murbartian J., Arias J.M., Perez-Reyes E. Orientation of the calcium channel beta relative to the α12.2 subunit is critical for its regulation of channel activity. PLoS ONE 2008, 3:e3560.
59. Wang Y., Okamoto M., Schmitz F., Hofmann K., Sudhof T.C. Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature 1997, 388:593-598.
60. Wang Y., Sudhof T.C. Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins(small star, filled ). Genomics 2003, 81:126-137.
61. Wang Y., Sugita S., Sudhof T.C. The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. J. Biol. Chem. 2000, 275:20033-20044.
62. V2.1 voltage-gated calcium channels. Channels (Austin) 2008, 2:461-473.
63. v1.3α1L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J. Neurosci. 2001, 21:5944-5951.
64. v1.3 channels by calcium binding proteins of auditory hair cells. J. Neurosci. 2006, 26:10677-10689.
65. 2+ channels expressed in mouse cochlear inner hair cells. J. Physiol. 2010, 588:187-199.
66. v1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB. Eur. J. NeuroSci. 2006, 23:2297-2310.