Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits β3 or β4

Channels

Volumn 3, Issue 5, 2009, Pages 366-376

  Kuhn, Stephanie ^a,c   Knirsch, Martina ^a   Rüttiger, Lukas ^a   Kasperek, Sylvia ^a   Winter, Harald ^a   Freichel, Marc ^b   Flockerzi, Veit ^b   Knipper, Marlies ^a   Engel, Jutta ^a,b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Activation kinetics; Auxiliary subunit; Inner hair cell; Lethargic; Outer hair cell; Voltage activated Ca2+ channel

Indexed keywords

BARIUM ION; CALCIUM; ESTRADIOL BENZOATE PLUS PROGESTERONE; MESSENGER RNA; VOLTAGE GATED CALCIUM CHANNEL; BARIUM; CACNB3 PROTEIN, MOUSE; CACNB3 PROTEIN, RAT; CACNB4 PROTEIN, MOUSE; CACNB4 PROTEIN, RAT; CALCIUM CHANNEL;

ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BETA CHAIN; CELL SIZE; CHEMICAL ANALYSIS; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; DELETION MUTANT; ELECTRIC POTENTIAL; HAIR CELL; HEARING; KINETICS; KNOCKOUT MOUSE; MEMBRANE CURRENT; MOUSE; MUTANT; NERVE FIBER; NONHUMAN; RAT; SYNAPTIC TRANSMISSION; WILD TYPE; ANIMAL; CHEMISTRY; CYTOLOGY; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; WISTAR RAT;

MUS;

ANIMALS; BARIUM; CALCIUM; CALCIUM CHANNELS; COCHLEA; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; HAIR CELLS, AUDITORY; HEARING; IMMUNOHISTOCHEMISTRY; KINETICS; MICE; RATS; RATS, WISTAR; SYNAPTIC TRANSMISSION;

EID: 70349267584     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.3.5.9774     Document Type: Article

References (53)

1. Ertel EA, Campbell KP, Harpold MM, Hofmann F, Mori Y, Perez-Reyes E, et al. Nomenclature of voltage-gated calcium channels. Neuron 2000; 25:533-535
2. 2+ channels. Annu Rev Cell Dev Biol 2000; 16:521-555
3. Arikkath J, Campbell KP. Auxiliary subunits: essential components of the voltage-gated calcium channel complex. Curr Opin Neurobiol 2003; 13:298-307. (Pubitemid 36792242)
4. Dolphin AC. Beta subunits of voltage-gated calcium channels. J Bioenerg Biomembr 2003; 35:599-620. (Pubitemid 38124815)
5. 2+ channels with gene knockout models. Channels (Austin) 2008; 2:233-251
6. Hidalgo P, Neely A. Multiplicity of protein interactions and functions of the voltage-gated calcium channel beta-subunit. Cell Calcium 2007; 42:389-396 (Pubitemid 47264011)
7. 2+ channels. Biophys J 2007; 93:834-845
8. Gregg RG, Messing A, Strube C, Beurg M, Moss R, Behan M, et al. Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha1 subunit and eliminates excitation-contraction coupling. Proc Natl Acad Sci USA 1996; 93:13961-13966 (Pubitemid 26424228)
9. Ball SL, Powers PA, Shin HS, Morgans CW, Peachey NS, Gregg RG. Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci 2002; 43:1595-1603
10. Ludwig A, Flockerzi V, Hofmann F. Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain. J Neurosci 1997; 17:1339-1349 (Pubitemid 27073735)
11. Vance CL, Begg CM, Lee WL, Haase H, Copeland TD, McEnery MW. Differential expression and association of calcium channel alpha1B and beta subunits during rat brain ontogeny. J Biol Chem 1998; 273:14495-14502 (Pubitemid 28319171)
12. Brandt A, Striessnig J, Moser T. CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells. J Neurosci 2003; 23:10832-10840 (Pubitemid 37499690)
13. 2+ channels in mature outer hair cells supports outer hair cell afferent signaling. J Neurosci 2007; 27:6442-6451
14. 2+ channels. Cell 2000; 102:89-97.
15. 2+ channel gene results in deafness but no vestibular defect in mice. J Assoc Res Otolaryngol 2004; 5:215-226
16. Ehret G. Behavioural studies on auditory development in mammals in relation to higher nervous system functioning. Acta Otolaryngol Suppl 1985; 421:31-40. (Pubitemid 15058253)
17. Kros CJ, Ruppersberg JP, Rusch A. Expression of a potassium current in inner hair cells during development of hearing in mice. Nature 1998; 394:281-284 (Pubitemid 28335040)
18. Beutner D, Moser T. The presynaptic function of mouse cochlear inner hair cells during development of hearing. J Neurosci 2001; 21:4593-4599 (Pubitemid 32565618)
19. Marcotti W, Johnson SL, Rusch A, Kros CJ. Sodium and calcium currents shape action potentials in immature mouse inner hair cells. J Physiol 2003; 552:743-761 (Pubitemid 37428417)
20. 2+ currents in neonatal outer hair cells of mice. J Physiol 2003; 553:747-758
21. 2+ channels activating at negative voltages. J Biol Chem 2001; 276:22100-22106
22. Lipscombe D, Helton TD, Xu W. L-type calcium channels: the low down. J Neurophysiol 2004; 92:2633-2641 (Pubitemid 40340475)
23. Hullin R, Khan IF, Wirtz S, Mohacsi P, Varadi G, Schwartz A, et al. Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics. J Biol Chem 2003; 278:21623-21630 (Pubitemid 36792562)
24. 2+ dependence of exocytosis during development of mouse inner hair cells. J Physiol 2005; 563:177-191
25. Green GE, Khan KM, Beisel DW, Drescher MJ, Hatfield JS, Drescher DG. Calcium channel subunits in the mouse cochlea. J Neurochem 1996; 67:37-45.
26. 2+-channel beta4 subunit. Proc Natl Acad Sci USA 2003; 100:307-312
27. Brandt A, Khimich D, Moser T. Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. J Neurosci 2005; 25:11577-11585 (Pubitemid 43098450)
28. Simmons DD. Development of the inner ear efferent system across vertebrate species. J Neurobiol 2002; 53:228-250
29. Pujol R, Lavigne-Rebillard M, Lenoir M. Development of sensory and neural structures in the mammalian cochlea. In: Rubel E, Popper A, Fay R, eds. Development of the auditory system. Springer Handbook of Auditory Research. New York: Springer 1997; 156-192
30. Murakami M, Fleischmann B, De Felipe C, Freichel M, Trost C, Ludwig A, et al. Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. J Biol Chem 2002; 277:40342-40351 (Pubitemid 35215607)
31. 2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell 1997; 88:385-392
32. 2+-dependent signaling pathways regulate the motor output of cochlear outer hair cells. J Neurosci 2000; 20:5940-5948
33. 2+: underlying mechanism and implications for cochlear mechanics. Cell Calcium 2003; 33:185-195
34. 2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci USA 2004; 101:12922-12927
35. 2+ channels. Trends Neurosci 2001; 24:176-181
36. 2+ channels by beta-subunits. J Physiol 2000; 527:445-454
37. 2+ currents recorded with the ancillary beta1-4 subunits. Receptors Channels 1997; 5:1-14.
38. Piper M, Holt C. RNA translation in axons. Annu Rev Cell Dev Biol 2004; 20:505-523
39. Sotelo-Silveira JR, Calliari A, Kun A, Koenig E, Sotelo JR. RNA trafficking in axons. Traffic 2006; 7:508-515
40. Pyott SJ, Meredith AL, Fodor AA, Vazquez AE, Yamoah EN, Aldrich RW. Cochlear function in mice lacking the BK channel alpha, beta1 or beta4 subunits. J Biol Chem 2007; 282:3312-3324
41. Oliver D, Taberner AM, Thurm H, Sausbier M, Arntz C, Ruth P, et al. The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neurosci 2006; 26:6181-6189
42. Yagi T, Macleish PR. Ionic conductances of monkey solitary cone inner segments. J Neurophysiol 1994; 71:656-665 (Pubitemid 24068595)
43. Morgans CW. Localization of the alpha(1F) calcium channel subunit in the rat retina. Invest Ophthalmol Vis Sci 2001; 42:2414-2418 (Pubitemid 32848874)
44. Liss B. Improved quantitative real-time RT-PCR for expression profiling of individual cells. Nucleic Acids Res 2002; 30:89.
45. Barber RD, Harmer DW, Coleman RA, Clark BJ. GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues. Physiol Genomics 2005; 21:389-395 (Pubitemid 40898499)
46. Knipper M, Bandtlow C, Gestwa L, Kopschall I, Rohbock K, Wiechers B, et al. Thyroid hormone affects Schwann cell and oligodendrocyte gene expression at the glial transition zone of the VIIIth nerve prior to cochlea function. Development 1998; 125:3709-3718 (Pubitemid 28469971)
47. Knipper M, Zinn C, Maier H, Praetorius M, Rohbock K, Kopschall I, et al. Thyroid hormone deficiency before the onset of hearing causes irreversible damage to peripheral and central auditory systems. J Neurophysiol 2000; 83:3101-3112 (Pubitemid 30321497)
48. 2+ oscillation frequency and insulin exocytosis. Cell 2004; 119:273-284
49. -/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation. Circ Res 2006; 99:749-757
50. Engel J, Braig C, Ruttiger L, Kuhn S, Zimmermann U, Blin N, et al. Two classes of outer hair cells along the tonotopic axis of the cochlea. Neuroscience 2006; 143:837-849 (Pubitemid 44751366)
51. Neher E. Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol 1992; 207:123-131
52. Zidanic M, Fuchs PA. Kinetic analysis of barium currents in chick cochlear hair cells. Biophys J 1995; 68:1323-1336
53. Hille B. Ionic channels of excitable membranes. Sunderland, MA: Sinauer Associates 1991.