Induction of apoptosis by the ginsenoside Rh2 by internalization of lipid rafts and caveolae and inactivation of Akt

British Journal of Pharmacology

Volumn 160, Issue 5, 2010, Pages 1212-1223

  Park, E K ^a   Lee, E J ^a   Lee, S H ^a   Koo, K H ^a   Sung, J Y ^a   Hwang, E H ^a   Park, J H ^b   Kim, C W ^b   Jeong, K C ^a   Park, B K ^a   Kim, Y N ^a  

^a National Cancer Center   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Akt; Apoptosis; Cholesterol; Ginsenosides; Lipid rafts and caveolae

Indexed keywords

ANTINEOPLASTIC AGENT; BIM PROTEIN; CHOLESTEROL; GINSENOSIDE RH 2; PROTEIN BAD; PROTEIN BAX; PROTEIN KINASE B; APOPTOSIS REGULATORY PROTEIN; GINSENOSIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; CARCINOMA CELL; CAVEOLA; CELL DEATH; CELL MEMBRANE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; DRUG EFFECT; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INTERNALIZATION; LIPID RAFT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA; WILD TYPE; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; FEMALE; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CAVEOLAE; CELL LINE, TUMOR; CELL MEMBRANE; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GINSENOSIDES; HUMANS; MALE; MEMBRANE MICRODOMAINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77953222632     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00768.x     Document Type: Article

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