Molecular study on copper-mediated tumor proteasome inhibition and cell death

International Journal of Oncology

Volumn 37, Issue 1, 2010, Pages 81-87

  Xiao, Yan ^a,b,c   Chen, Di ^a   Zhang, Xia ^a,b   Cui, Qiuzhi ^a   Fan, Yuhua ^b   Bi, Caifeng ^b   Dou, Q Ping ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OCEAN UNIVERSITY OF CHINA   (China)

^c QINGDAO INSTITUTE OF BIOENERGY AND BIOPROCESS TECHNOLOGY   (China)

Author keywords

Apoptosis; Copper; Oxidation status; Proteasome inhibition; ROS

Indexed keywords

CHYMOTRYPSIN; COPPER; CUPROUS ION; PROTEASOME INHIBITOR; REACTIVE OXYGEN METABOLITE; TUMOR PROTEIN; UBIQUITIN; 2,9 DIMETHYL 1,10 PHENANTHROLINE; CHELATING AGENT; CUPRIC CHLORIDE; CUPROUS CHLORIDE; PHENANTHROLINE DERIVATIVE; PROTEASOME; PROTEINASE INHIBITOR;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CELL DEATH; CELL GROWTH; CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LEUKEMIA CELL LINE; MOLECULAR BIOLOGY; OXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SYNTHESIS; TUMOR XENOGRAFT; WESTERN BLOTTING; BREAST TUMOR; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; JURKAT CELL LINE; LEUKEMIA; METABOLISM; NEOPLASM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

BREAST NEOPLASMS; CELL DEATH; CHELATING AGENTS; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; JURKAT CELLS; LEUKEMIA; NEOPLASMS; PHENANTHROLINES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 77953218928     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo-00000655     Document Type: Article

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