Knockdown of STAT3 expression by RNAi suppresses growth and induces apoptosis and differentiation in glioblastoma stem cells

International Journal of Oncology

Volumn 37, Issue 1, 2010, Pages 103-110

  Li, Guang Hui ^a   Wei, Hong ^a   Lv, Sheng Qing ^a   Ji, Hua ^b   Wang, Dong Lin ^a,c  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b KUNMING GENERAL HOSPITAL   (China)

^c SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Apoptosis; Cancer stem cell; Glioblastoma; Self renewal; STAT3

Indexed keywords

BETA ACTIN; CASPASE 3; CYCLIN D; PROTEIN BAX; PROTEIN BCL 2; RNA; STAT3 PROTEIN; SMALL INTERFERING RNA; STAT3 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CANCER INHIBITION; CANCER STEM CELL; CANCER TRANSPLANTATION; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; EMBRYONIC STEM CELL; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE SILENCING; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LENTIVIRINAE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RNA INTERFERENCE; TUMOR GROWTH; ANIMAL; ANTAGONISTS AND INHIBITORS; CENTRAL NERVOUS SYSTEM TUMOR; DOWN REGULATION; DRUG EFFECTS; DRUG SCREENING; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL CULTURE; UPREGULATION;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM NEOPLASMS; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; GLIOBLASTOMA; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASTIC STEM CELLS; RNA, SMALL INTERFERING; STAT3 TRANSCRIPTION FACTOR; TUMOR CELLS, CULTURED; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77953207270     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000658     Document Type: Article

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