Protocol for the examination of specimens from patients with carcinoma of the penis

Archives of Pathology and Laboratory Medicine

Volumn 134, Issue 6, 2010, Pages 923-929

  Velazquez, Elsa F ^a   Amin, Mahul B ^b   Epstein, Jonathan I ^c   Grignon, David J ^d   Humphrey, Peter A ^e   Pettaway, Curtis A ^f   Renshaw, Andrew A ^g   Reuter, Victor E ^h   Srigley, John R ⁱ   Cubilla, Antonio L ^j  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Cedars Sinai Medical Center   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

^d INDIANA UNIVERSITY   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF TEXAS   (United States)

^g BAPTIST HOSPITAL OF MIAMI   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ CREDIT VALLEY HOSPITAL   (Canada)

^j UNIVERSIDAD NACIONAL DE ASUNCIÓN   (Paraguay)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOPSY; CANCER STAGING; CLASSIFICATION; CLINICAL PROTOCOL; EDUCATION; HUMAN; MALE; MEDICAL SOCIETY; PATHOLOGY; PENIS TUMOR; PROGNOSIS; UNITED STATES;

BIOPSY; CLINICAL PROTOCOLS; HUMANS; MALE; NEOPLASM STAGING; PATHOLOGY, CLINICAL; PENILE NEOPLASMS; PROGNOSIS; SOCIETIES, MEDICAL; UNITED STATES;

EID: 77953203248     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Edge SB, Byrd DR, Carducci MA, Compton CC, eds. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer; 2009.
2. Velazquez EF, Bock A, Soskin A, Codas R, Arbo M, Cubilla AL. Preputial variability and preferential association of long phimotic foreskins with penile cancer: an anatomic comparative study of types of foreskin in a general population and cancer patients. Am J Surg Pathol. 2003;27(7):994-998.
3. Daling J, Madeleine MM, Johnson LG, et al. Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease. Int J Cancer. 2005;116(4):606-616.
4. Tsen HF, Morgenstern H, Mack T, Peters RK. Risk factors for penile cancer: results of a population-based case-control study in Los Angeles County (United States). Cancer Causes Control. 2002;12(3):267-277.
5. Madsen BS, van den Brule AJ, Jensen HL, Wholfahrt J, Frisch M. Risk factors for squamous cell carcinoma of the penis: population-based case-control study in Denmark. Cancer Epidemiol Biomarkers Prev. 2008;17(10):2683-2691.
6. Lont AP, Kroon BK, Gallee MP, van Tinteren H, Moonen LM, Horenblas S. Pelvic lymph node dissection for penile carcinoma: extent of inguinal lymph node involvement as an indicator for pelvic lymph node involvement and survival. J Urol. 2007;177(3):947-952.
7. Svatek RS, Munsell M, Kincaid JM, et al. Association between lymph node density and disease specific survival in patients with penile cancer. J Urol. 2009;182(6):2721-2727.
8. Pandey D, Mahajan V, Kannan RR. Prognostic factors in node-positive carcinoma of the penis. J Surg Oncol. 2006;93(2):133-138.
9. Guimarães G, Lopes A, Campos RS, et al. Front pattern of invasion in squamous cell carcinoma of the penis: new prognostic factor for predicting risk of lymph node metastases. Urology. 2006;68(1):148-153.
10. Epstein JH, Humphrey PA, Cubilla AL. Tumors of the Prostate Gland, Seminal Vesicles, Male Urethra, Penis and Scrotum. Washington, DC: Armed Forces Institute of Pathology. In press. Atlas of Tumor Pathology.
11. Cubilla AL, Dillner J, Schellhammer PF, Horenblas S. Malignant epithelial tumors. In: Eble JN, Sauter G, Epstein J, Sesterhenn I, eds. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon, France: IARC Press; 2004. World Health Organization Classification of Tumours; vol 7.
12. Velazquez EF, Barreto JE, Ayala G, Cubilla AL. Penis. In: Mills SE, Carter D, Greenson JK, et al, eds. Sternberg's Diagnostic Surgical Pathology. 5th ed. Philadelphia, PA: Lippincot Williams & Wilkins; 2009: 2005-2047.
13. Cubilla AL, Reuter V, Velazquez E, Piris A, Saito S, Young RH. Histologic classification of penile carcinoma and its relation to outcome in 61 patients with primary resection. Int J Surg Pathol. 2001;9(2):111-120.
14. Cubilla AL, Velazques EF, Reuter VE, Oliva E, Mihm MC Jr, Young RH. Warty (condylomatous) squamous cell carcinoma of the penis: a report of 11 cases and proposed classification of 'verruciform' penile tumors. Am J Surg Pathol. 2000;24(4):505-512.
15. Cubilla AL, Velazquez EF, Young RH. Pseudohyperplastic squamous cell carcinoma of the penis associated with lichen sclerosus-an extremely welldifferentiated nonverruciform neoplasm that preferentially affects the foreskin and is frequently misdiagnosed: a report of 10 cases of a distinctive clinicopathologic entity. Am J Surg Pathol. 2004;28(7):895-900.
16. Barreto JE, Velazquez EF, Ayala E, Torres J, Cubilla AL. Carcinoma cuniculatum of the penis-a distinctive variant of penile squamous cell carcinoma: report of 7 cases. Am J Surg Pathol. 2007;31(1):71-75.
17. Cubilla AL, Reuter VE, Gregoire L, et al. Basaloid squamous cell carcinoma: a distinctive HPV related penile neoplasm: a report of 20 cases. Am J Surg Pathol. 1998;22(6):751-761.
18. Velazquez EF, Melamed J, Barreto JE, Aguero F, Cubilla AL. Sarcomatoid carcinoma of the penis: a clinico-pathological study of 14 cases. Am J Surg Pathol. 2005;29(9):1152-1158.
19. Cubilla AL, Ayala MT, Barreto JE, Bellasai JG, Nöel JC. Surface adenosquamous carcinoma of the penis: a report of three cases. Am J Surg Pathol. 1996;20(2):156-160.
20. Slaton JW, Morgenstern N, Levy DA, et al. Tumor stage, vascular invasion and the percentage of poorly differentiated cancer: independent prognosticators for inguinal node metastasis in penile squamous cancer. J Urol. 2001;165(4):1138-1142.
21. Cubilla AL, Velazquez EF, Ayala GE, Chaux A, Torres J, Reuter V. Identification of prognostic pathologic parameters in squamous cell carcinoma of the penis: significance and difficulties. Pathol Case Rev. 2005;10: 3-13.
22. Velazquez EF, Ayala G, Liu H, et al. Histologic grade and perineural invasion are more important than tumor thickness as predictor of nodal metastasis in penile squamous cell carcinoma invading 5 to 10 mm. Am J Surg Pathol. 2008;32(7):974-979.
23. Chaux A, Torres J, Pfannl R, et al. Histologic grade in penile squamous cell carcinoma: visual estimation versus digital measurement of proportions of grades, adverse prognosis with any proportion of grade 3 and correlation of a Gleasonlike system with nodal metastasis. Am J Surg Pathol. 2009;33: 1042-1048.
24. Emerson RE, Ulbright TM, Eble JN, Geary WA, Eckert GJ, Cheng L. Predicting cancer progression in patients with penile squamous cell carcinoma: the importance of depth of invasion and vascular invasion. Mod Pathol. 2001;14(10):963-968.
25. Guimaraes GC, Cunha IW, Soares FA, et al. Penile squamous cell carcinoma clinicopathological features, nodal metastasis and outcome in 333 cases. J Urol. 2009;182(2):528-534.
26. Leijte J, Gallee M, Antonini N, Horenblas S. Evaluation of current TNM classification of penile carcinoma. J Urol. 2008;180(3):933-938.
27. Chaux A, Caballero C, Soares F, et al. The prognostic index: a useful pathologic guide for prediction of nodal metastases and survival in penile squamous cell carcinoma. Am J Surg Pathol. 2009;33(7):1049-1057.
28. Velazquez EF, Soskin A, Bock A, Codas R, Barreto JE, Cubilla AL. Positive resection margins in partial penectomies: sites of involvement and proposal of local routes of spread of penile squamous cell carcinoma. Am J Surg Pathol. 2004;28(3):384-389.
29. Lopes A, Hidalgo GS, Kowalski LP, Torloni H, Rossi BM, Fonseca FP. Prognostic factors in carcinoma of the penis: multivariate analysis of 145 patients treated with amputation and lymphadenectomy. J Urol. 1996;156(5):1637-1642.
30. Ficarra V, Zattoni F, Cunisco SC, et al. Lymphatic and vascular embolizations are independent predictive variables of inguinal node involvement in patients with squamous cell carcinoma of the penis: Gruppo Uro-Oncologico del Nord Est (Northeast Uro-Oncological Group) Penile Cancer data base data. Cancer. 2005;103(12):2507-2516.
31. Ficarra V, Zattoni F, Artibani W, et al. Nomogram predictive of pathological inguinal lymph node involvement in patients with squamous cell carcinoma of the penis. J Urol. 2006;175(6):1700-1705.
32. Kattan MW, Ficarra V, Artibani W, et al. Nomogram predictive of cancer specific survival in patients undergoing partial or total amputation for squamous cell carcinoma of the penis. J Urol. 2006;175(6):2103-2108.
33. Novara G, Galfano A, De Marco V, Artibani W, Ficarra V. Prognostic factors in squamous cell carcinoma of the penis. Nat Clin Pract Urol. 2007;4(3):140-146. (Pubitemid 46416278)
34. Solsona E, Algaba F, Horenblas S, Pizzocaro G, Windahl T.; European Association of Urology. EAU guidelines on penile cancer. Eur Urol. 2004;46(1):1-8.
35. Solsona E, Iborra I, Rubio J, Casanova JL, Ricos JV, Calabuig C. Prospective validation of the association of local tumor stage and grade as a predictive factor for occult lymph node micrometastasis in patients with penile carcinoma and clinically negative inguinal lymph nodes. J Urol. 2001;165(5):1506-1509.
36. Hungerhuber E, Schlenker B, Karl A, et al. Risk stratification in penile carcinoma: 25-year experience with surgical inguinal lymph node staging. Urology. 2006;68(3):621-625.
37. Ornellas AA, Nóbrega BL, Wei Kin Chin E, et al. Prognostic factors in invasive squamous cell carcinoma of the penis: analysis of 196 patients treated at the Brazilian National Cancer Institute. J Urol. 2008;180(4):1354- 1359.
38. Cubilla AL, Pfannl R, Rodriguez I, et al. Morphological characterization and distribution of penile precancerous lesions using a simplified nomenclature: a study of 198 lesions in 115 patients. Lab Invest. 2008;88:696(A).
39. Pfannl R, Hernandez M, Velazquez EF, et al. Expression of p53 and p16 in differentiated and warty/basaloid penile intraepithelial neoplasia (PeIN). Lab Invest. 2008;88:807(A).
40. Cubilla AL, Piris A, Pfanni R, Rodriguez I, Agüero F, Young RH. Anatomic levels: important landmarks in penectomy specimens; a detailed anatomic and histologic study based on the examination of 44 specimens. Am J Surg Pathol. 2001;25: 1091-1094.