-
1
-
-
0002552327
-
-
White, E. H.; Rapaport, E.; Seliger, H. H.; Hopkins, T. A. Bioorg. Chem. 1971, 1, 92.
-
(1971)
Bioorg. Chem.
, vol.1
, pp. 92
-
-
White, E.H.1
Rapaport, E.2
Seliger, H.H.3
Hopkins, T.A.4
-
2
-
-
2442437836
-
-
Roda, A.; Pasini, P.; Mirasoli, M.; Michelini, E.; Guardigli, M. Trends Biotechnol. 2004, 22, 295.
-
(2004)
Trends Biotechnol.
, vol.22
, pp. 295
-
-
Roda, A.1
Pasini, P.2
Mirasoli, M.3
Michelini, E.4
Guardigli, M.5
-
6
-
-
0034760638
-
-
For luciferase-mediated gene imaging a dose of 125 mg/Kg of D-luciferin is required
-
For luciferase-mediated gene imaging a dose of 125 mg/Kg of D-luciferin is required: Wu, J. C.; Sundaresan, G.; Iyer, M.; Gambhir, S. S. Mol. Ther. 2001, 4, 297.
-
(2001)
Mol. Ther.
, vol.4
, pp. 297
-
-
Wu, J.C.1
Sundaresan, G.2
Iyer, M.3
Gambhir, S.S.4
-
8
-
-
29444443670
-
-
(b) Iyer, M.; Sato, M.; Johnson, M.; Gambhir, S. S.; Wu, L. Curr. Gene Ther. 2005, 5, 607.
-
(2005)
Curr. Gene Ther.
, vol.5
, pp. 607
-
-
Iyer, M.1
Sato, M.2
Johnson, M.3
Gambhir, S.S.4
Wu, L.5
-
11
-
-
28044441148
-
-
Wang, J.-Q.; Pollok, K. E.; Cai, S.; Stantz, K. M.; Hutchins, G. D.; Zheng, Q.-H. Bioorg. Med. Chem. Lett. 2006. 16, 331.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 331
-
-
Wang, J.-Q.1
Pollok, K.E.2
Cai, S.3
Stantz, K.M.4
Hutchins, G.D.5
Zheng, Q.-H.6
-
12
-
-
1242316924
-
-
Lee, S.-Y.; Choe, Y. S.; Lee, K.-H.; Lee, J.; Choi, Y.; Kim, B.-T. Bioorg. Med. Chem Lett. 2004, 14, 1161.
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 1161
-
-
Lee, S.-Y.1
Choe, Y.S.2
Lee, K.-H.3
Lee, J.4
Choi, Y.5
Kim, B.-T.6
-
13
-
-
1242334653
-
-
Lee, K. H.; Byun, S.; Paik, J. Y.; Song, S. H.; Choe, Y. S.; Kim, B. T. Nucl. Med. Commun. 2003, 24, 1003.
-
(2003)
Nucl. Med. Commun.
, vol.24
, pp. 1003
-
-
Lee, K.H.1
Byun, S.2
Paik, J.Y.3
Song, S.H.4
Choe, Y.S.5
Kim, B.T.6
-
14
-
-
0037234105
-
-
Ciana, P.; Raviscioni, M.; Mussi, P.; Vegeto, E.; Que, I.; Parker, M. G.; Lowik, C.; Maggi, A. Nature Medicine 2003, 9, 82.
-
(2003)
Nature Medicine
, vol.9
, pp. 82
-
-
Ciana, P.1
Raviscioni, M.2
Mussi, P.3
Vegeto, E.4
Que, I.5
Parker, M.G.6
Lowik, C.7
Maggi, A.8
-
15
-
-
0014595824
-
-
Denburg, J. L.; Lee, R. T.; McElroy, W. D. Archiv. Biochem. Biophys. 1969, 134, 381.
-
(1969)
Archiv. Biochem. Biophys.
, vol.134
, pp. 381
-
-
Denburg, J.L.1
Lee, R.T.2
McElroy, W.D.3
-
17
-
-
85069247298
-
-
For instance, we have attempted to prepare 6'-O-methyl luciferin 1d from D-luciferin 1a. The methylation of compound 1a under a variety of experimental conditions afforded mixture of products, due to the instability of D-luciferin itself and also a few attempts of radiosynthesis failed. Starting from the methyl ester of D-luciferin, the corresponding 11C methyl ether has later been prepared by reaction with 11C-CH3OTf.7
-
For instance, we have attempted to prepare 6'-O-methyl luciferin 1d from D-luciferin (1a). The methylation of compound 1a under a variety of experimental conditions afforded mixture of products, due to the instability of D-luciferin itself and also a few attempts of radiosynthesis failed. Starting from the methyl ester of D-luciferin, the corresponding [11C] methyl ether has later been prepared by reaction with [11C]-CH3OTf.7
-
-
-
-
18
-
-
43049136225
-
-
Auld, D. S.; Southall, N. T.; Jadhav, A.; Johnson, R. L.; Diller, D. J.; Simeonov, A.; Austin, C. P.; Inglese, J. J. Med. Chem. 2008, 51, 2372.
-
(2008)
Med. Chem.
, vol.51
, pp. 2372
-
-
Auld, D.S.1
Southall, N.T.2
Jadhav, A.3
Johnson, R.L.4
Diller, D.J.5
Simeonov, A.6
Austin, C.P.7
Inglese, J.J.8
-
19
-
-
0001555145
-
-
White, E.; McCapra, F.; Field, G. F. J. Am. Chem. Soc. 1963, 85, 337.
-
(1963)
Am. Chem. Soc.
, vol.85
, pp. 337
-
-
White, E.1
McCapra, F.2
Field, G.F.J.3
-
20
-
-
12944294406
-
-
Seto, S.; Ogura, K.; Nishiyama, Y. Bull. Chem. Soc. Jpn. 1963, 36, 332.
-
(1963)
Bull. Chem. Soc. Jpn.
, vol.36
, pp. 332
-
-
Seto, S.1
Ogura, K.2
Nishiyama, Y.3
-
21
-
-
0013635627
-
-
Toya, Y.; Takagi, M.; Nakata, H.; Suzuki, N.; Isobe, M.; Goto, T. Bull. Chem. Soc. Jpn. 1992, 65, 392.
-
(1992)
Bull. Chem. Soc. Jpn.
, vol.65
, pp. 392
-
-
Toya, Y.1
Takagi, M.2
Nakata, H.3
Suzuki, N.4
Isobe, M.5
Goto, T.6
-
22
-
-
4444328597
-
-
Suzuki, N.; Nomoto, T.; Toya, Y.; Kanamori, N.; Yoda, B.; Saeki, A. Biosci. Biotech. Biochem. 1993, 57, 1561.
-
(1993)
Biosci. Biotech. Biochem.
, vol.57
, pp. 1561
-
-
Suzuki, N.1
Nomoto, T.2
Toya, Y.3
Kanamori, N.4
Yoda, B.5
Saeki, A.6
-
23
-
-
85069238703
-
-
We have also tried other reagents for the demethylation step such as BBr3 or trimethylsilyl iodide, but the nitrile moiety reacted as well and the yields of the transformation were considerably lowered
-
We have also tried other reagents for the demethylation step such as BBr3 or trimethylsilyl iodide, but the nitrile moiety reacted as well and the yields of the transformation were considerably lowered.
-
-
-
-
24
-
-
0034814944
-
-
Löwik, D. P. W.; Tisi, L. C.; Murray, J. A. H.; Lowe, C. R. Synthesis 2001, 1780.
-
(2001)
Synthesis
, pp. 1780
-
-
Löwik, D.P.W.1
Tisi, L.C.2
Murray, J.A.H.3
Lowe, C.R.4
-
28
-
-
33644680778
-
-
Mateo, C.; Chmura, A.; Rustler, S.; van Rantwijk, F.; Stolz, A.; Sheldon, R. A. Tetrahedron Asymm. 2006, 17, 320.
-
(2006)
Tetrahedron. Asymm
, vol.17
, pp. 320
-
-
Mateo, C.1
Chmura, A.2
Rustler, S.3
Van Rantwijk, F.4
Stolz, A.5
Sheldon, R.A.6
-
29
-
-
33646807836
-
-
Mukherjee C.; Zhu, D.; Biehl E. R.; Parmar, R. R.; Hua, L. Tetrahedron 2006, 62, 6150.
-
(2006)
Tetrahedron.
, vol.62
, pp. 6150
-
-
Mukherjee, C.1
Zhu, D.2
Biehl, E.R.3
Parmar, R.R.4
Hua, L.5
-
30
-
-
0013676737
-
-
Amess, R.; Baggett, N.; Darby, P. R.; Goode, A. R. Carbohydr. Res. 1990, 205, 225.
-
(1990)
Carbohydr. Res.
, vol.205
, pp. 225
-
-
Amess, R.1
Baggett, N.2
Darby, P.R.3
Goode, A.R.4
-
31
-
-
0031784872
-
-
Franks N. P.; Jenkins, A.; Conti, E.; Lieb, W. R.; Brick, P. Biophys. J. 1998, 75, 2205.
-
(1998)
Biophys. J.
, vol.75
, pp. 2205
-
-
Franks, N.P.1
Jenkins, A.2
Conti, E.3
Lieb, W.R.4
Brick, P.5
-
32
-
-
0025970573
-
-
Moss, G. W. J.; Franks, N. P.; Lieb, W. R. Proc. Natl. Acad. Sci. USA 1991, 88, 134.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 134
-
-
Moss, G.W.J.1
Franks, N.P.2
Lieb, W.R.3
-
34
-
-
33750508964
-
-
Bakhtiarova, A.; Taslimi, P.; Elliman, S. J.; Kosinski, P. A.; Hubbard, B.; Kavana, M.; Kemp, D. M. Biochem. Biophys. Res. Commun. 2006, 351, 481.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 481
-
-
Bakhtiarova, A.1
Taslimi, P.2
Elliman, S.J.3
Kosinski, P.A.4
Hubbard, B.5
Kavana, M.6
Kemp, D.M.7
|