Synthesis of 7′-[123I]iodo-D-luciferin for in vivo studies of firefly luciferase gene expression

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 5, 2004, Pages 1161-1163

  Lee, Sang Yoon ^a,b   Choe, Yearn Seong ^a   Lee, Kyung Han ^a   Lee, Jeewoo ^b   Choi, Yong ^a   Kim, Byung Tae ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

7 123I iodo D luciferin; Firefly luciferase; Gene expression; Luminescence assay

Indexed keywords

7' IODO DEXTRO LUCIFERIN I 123; IODINE 123; LUCIFERASE; LUCIFERIN; UNCLASSIFIED DRUG; RADIOACTIVE IODINE;

ARTICLE; BINDING AFFINITY; GENE EXPRESSION; IN VIVO STUDY; LUMINESCENCE; RADIOACTIVITY; STANDARDIZATION; SYNTHESIS; ANIMAL; BEETLE; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY;

ANIMALS; BEETLES; FIREFLY LUCIFERIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IODINE RADIOISOTOPES; LUCIFERASES;

EID: 1242316924     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.066     Document Type: Article

References (24)

1. Wood K.V. Curr. Opin. Biotechnol. 6:1995;50.
2. Haberkorn U., Altmann A. Curr. Gene Ther. 1:2001;163.
3. Daiz-Sandoval L.J., Losordo D.W. Expert. Opin. Biol. Ther. 3:2003;599.
4. Otsu M., Hershfield M.S., Tuschong L.M., Muul L.M., Onodera M., Ariga T., Sakiyama Y., Candotti F. Hum. Gene Ther. 13:2002;425.
5. Yang L., Lochmuller H., Luo J., Massie B., Nalbantoglu J., Karpati G., Petrof B.J. Gene Ther. 5:1998;369.
6. Sharpe J., Ahlgren U., Perry P., Hill B., Ross A., Hecksher-Sorensen J., Baldock R., Davidson D. Science. 296:2002;541.
7. Hogemann D., Basilion J.P. Eur. J. Nucl. Med. Mol. Imaging. 29:2002;400.
8. Meade T. Acad. Radiol. 8:2001;1.
9. Bremer C., Weissleder R. Acad. Radiol. 8:2001;15.
10. Luker G.D., Piwnica-Worms D. Acad. Radiol. 8:2001;4.
11. Jacobs A., Heiss W.D. Vet. Microbiol. 86:2002;27.
12. Gambhir S.S., Barrio J.R., Phelps M.E., Iyer M., Namavari M., Satyamurthy N., Wu L., Green L.A., Bauer E., Maclaren D.C., Nguyen K., Berk A.J., Cherry S.R., Herschman H.R. Proc. Natl. Acad. Sci. 96:1999;2333.
13. Tjuvajev J.G., Doubrovin M., Akhurst T., Cai S., Balatoni J., Alauddin M.M., Finn R., Bornmann W., Thaler H., Conti P.S., Blasberg R.G. J. Nucl. Med. 43:2002;1072.
14. Naylor L.H. Biochem. Pharmacol. 58:1999;749.
15. Wu J.C., Sundaresan G., Iyer M., Gambhir S.S. Mol. Ther. 4:2001;297.
16. Barros M.P., Bechara E.J.H. Free Radical Biol. Med. 24:1998;767.
17. 2 406.9021, found 406.9032.
18. 2 (70-80°C). The concentrated product (∼1 mL) was diluted with saline.
19. Craig F.F., Simmonds A.C., Watmore D., McCapra F., White M.R.H. Biochem. J. 276:1991;637.
20. M was calculated using a Prism™ program.
21. Lembert N., Idahl L. Biochem. J. 305:1995;929.
22. Lembert N. Biochem. J. 317:1996;273.
23. Tomaso G.D., Borghese R., Zannoni D. Arch. Microbiol. 177:2001;11.
24. Lee K.-H., Byun S.S., Paik J.-Y., Lee S.Y., Song S.H., Choe Y.S., Kim B.-T. Nucl. Med. Commun. 24:2003;1003.