-
1
-
-
2342559981
-
The TOR pathway: a target for cancer therapy
-
Bjornsti M.A., and Houghton P.J. The TOR pathway: a target for cancer therapy. Nat. Rev. Cancer 4 (2004) 335-348
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
2
-
-
33750072949
-
mTOR and cancer therapy
-
Easton J.B., and Houghton P.J. mTOR and cancer therapy. Oncogene 25 (2006) 6436-6446
-
(2006)
Oncogene
, vol.25
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
-
4
-
-
33747819801
-
mTOR and cancer: insights into a complex relationship
-
Sabatini D.M. mTOR and cancer: insights into a complex relationship. Nat. Rev. Cancer 6 (2006) 729-734
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 729-734
-
-
Sabatini, D.M.1
-
5
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin D.A., and Sabatini D.M. Defining the role of mTOR in cancer. Cancer Cell 12 (2007) 9-22
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
7
-
-
54949144410
-
mTOR inhibitors in the treatment of cancer
-
Fasolo A., and Sessa C. mTOR inhibitors in the treatment of cancer. Expert Opin. Investig. Drugs 17 (2008) 1717-1734
-
(2008)
Expert Opin. Investig. Drugs
, vol.17
, pp. 1717-1734
-
-
Fasolo, A.1
Sessa, C.2
-
8
-
-
37449024702
-
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis R.J., Lum J.J., Hatzivassiliou G., and Thompson C.B. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 7 (2008) 11-20
-
(2008)
Cell Metab.
, vol.7
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
11
-
-
40949137463
-
A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells
-
Yaba A., Bianchi V., Borini A., and Johnson J. A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells. Reprod. Sci. 15 (2008) 128-138
-
(2008)
Reprod. Sci.
, vol.15
, pp. 128-138
-
-
Yaba, A.1
Bianchi, V.2
Borini, A.3
Johnson, J.4
-
12
-
-
4544315354
-
New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists
-
Carraway H., and Hidalgo M. New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists. Breast Cancer Res. 6 (2004) 219-224
-
(2004)
Breast Cancer Res.
, vol.6
, pp. 219-224
-
-
Carraway, H.1
Hidalgo, M.2
-
13
-
-
35348917266
-
Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency
-
Lu C.H., Wyszomierski S.L., Tseng L.M., Sun M.H., Lan K.H., Neal C.L., Mills G.B., Hortobagyi G.N., Esteva F.J., and Yu D. Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency. Clin. Cancer Res. 13 (2007) 5883-5888
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5883-5888
-
-
Lu, C.H.1
Wyszomierski, S.L.2
Tseng, L.M.3
Sun, M.H.4
Lan, K.H.5
Neal, C.L.6
Mills, G.B.7
Hortobagyi, G.N.8
Esteva, F.J.9
Yu, D.10
-
14
-
-
51849111524
-
NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
-
Serra V., Markman B., Scaltriti M., Eichhorn P.J., Valero V., Guzman M., Botero M.L., Llonch E., Atzori F., Di Cosimo S., Maira M., Garcia-Echeverria C., Parra J.L., Arribas J., and Baselga J. NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations. Cancer Res. 68 (2008) 8022-8030
-
(2008)
Cancer Res.
, vol.68
, pp. 8022-8030
-
-
Serra, V.1
Markman, B.2
Scaltriti, M.3
Eichhorn, P.J.4
Valero, V.5
Guzman, M.6
Botero, M.L.7
Llonch, E.8
Atzori, F.9
Di Cosimo, S.10
Maira, M.11
Garcia-Echeverria, C.12
Parra, J.L.13
Arribas, J.14
Baselga, J.15
-
15
-
-
7744222944
-
Chromosomal passengers: the four-dimensional regulation of mitotic events
-
Vagnarelli P., and Earnshaw W.C. Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma 113 (2004) 211-222
-
(2004)
Chromosoma
, vol.113
, pp. 211-222
-
-
Vagnarelli, P.1
Earnshaw, W.C.2
-
16
-
-
33745275629
-
The chromosomal passenger complex: guiding Aurora-B through mitosis
-
Vader G., Medema R.H., and Lens S.M. The chromosomal passenger complex: guiding Aurora-B through mitosis. J. Cell Biol. 173 (2006) 833-837
-
(2006)
J. Cell Biol.
, vol.173
, pp. 833-837
-
-
Vader, G.1
Medema, R.H.2
Lens, S.M.3
-
18
-
-
45249110707
-
Cytokinesis: the final stop for the chromosomal passengers
-
Carmena M. Cytokinesis: the final stop for the chromosomal passengers. Biochem. Soc. Trans. 36 (2008) 367-370
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 367-370
-
-
Carmena, M.1
-
19
-
-
1642294871
-
Kinesin superfamily protein member 4 (KIF4) is localized to midzone and midbody in dividing cells
-
Lee Y.M., and Kim W. Kinesin superfamily protein member 4 (KIF4) is localized to midzone and midbody in dividing cells. Exp. Mol. Med. 36 (2004) 93-97
-
(2004)
Exp. Mol. Med.
, vol.36
, pp. 93-97
-
-
Lee, Y.M.1
Kim, W.2
-
20
-
-
4444346337
-
Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation
-
Kurasawa Y., Earnshaw W.C., Mochizuki Y., Dohmae N., and Todokoro K. Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J. 23 (2004) 3237-3248
-
(2004)
EMBO J.
, vol.23
, pp. 3237-3248
-
-
Kurasawa, Y.1
Earnshaw, W.C.2
Mochizuki, Y.3
Dohmae, N.4
Todokoro, K.5
-
21
-
-
18844396190
-
Cleavage furrow formation and ingression during animal cytokinesis: a microtubule legacy
-
D'Avino P.P., Savoian M.S., and Glover D.M. Cleavage furrow formation and ingression during animal cytokinesis: a microtubule legacy. J. Cell Sci. 118 (2005) 1549-1558
-
(2005)
J. Cell Sci.
, vol.118
, pp. 1549-1558
-
-
D'Avino, P.P.1
Savoian, M.S.2
Glover, D.M.3
-
22
-
-
57349097151
-
Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis
-
Canman J.C., Lewellyn L., Laband K., Smerdon S.J., Desai A., Bowerman B., and Oegema K. Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science 322 (2008) 1543-1546
-
(2008)
Science
, vol.322
, pp. 1543-1546
-
-
Canman, J.C.1
Lewellyn, L.2
Laband, K.3
Smerdon, S.J.4
Desai, A.5
Bowerman, B.6
Oegema, K.7
|