Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion

Cancer Research

Volumn 70, Issue 11, 2010, Pages 4327-4334

  Malik, Gunjan ^a   Knowles, Lynn M ^a   Dhir, Rajiv ^a,b   Xu, Shuping ^a   Yang, Shuting ^a   Ruoslahti, Erkki ^c,d   Pilch, Jan ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c BURNHAM INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRIN; FIBRONECTIN; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; CARCINOMA CELL; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; FIBRIN CLOT; LEWIS CARCINOMA; LUNG METASTASIS; MELANOMA B16; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ANIMALS; BLOOD COAGULATION; CARCINOMA, LEWIS LUNG; CELL ADHESION; FIBRIN; FIBRONECTINS; INTEGRIN ALPHAVBETA3; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASM INVASIVENESS;

EID: 77953153938     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3312     Document Type: Article

References (50)

1. Brown DM, Ruoslahti E. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 2004; 5:365-374
2. Shibue T, Weinberg RA. Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A 2009;106:10290-10295
3. Im JH, Fu W, Wang H, et al. Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res 2004;64:8613-8619
4. Gorelik E, Bere WW, Herberman RB. Role of NK cells in the anti-metastatic effect of anticoagulant drugs. Int J Cancer 1984; 33:87-94. (Pubitemid 14223238)
5. Palumbo JS, Barney KA, Blevins EA, et al. Factor XIII transglutaminase supports hematogenous tumor cell metastasis through a mechanism dependent on natural killer cell function. J Thromb Haemost 2008;6:812-819
6. Palumbo JS, Talmage KE, Massari JV, et al. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells. Blood 2005;105:178-185
7. Aeschlimann D, Mosher D, Paulsson M. Tissue transglutaminase and factor XIII in cartilage and bone remodeling. Semin Thromb Hemost 1996;22:437-443 (Pubitemid 27050714)
8. Ruoslahti E. Fibronectin in cell adhesion and invasion. Cancer Metastasis Rev 1984;3:43-51.
9. Ruoslahti E. Fibronectin and its integrin receptors in cancer. Adv Cancer Res 1999;76:1-20. (Pubitemid 29190879)
10. Felding-Habermann B, Mueller BM, Romerdahl CA, Cheresh DA. Involvement of integrin αV gene expression in human melanoma tumorigenicity. J Clin Invest 1992;89:2018-2022
11. Felding-Habermann B, O'Toole TE, Smith JW, et al. Integrin activation controls metastasis in human breast cancer. Proc Natl Acad Sci U S A 2001;98:1853-1858
12. Humphries MJ, Olden K, Yamada KM. A synthetic peptide from fibronectin inhibits experimental metastasis of murine melanoma cells. Science 1986;233:467-470 (Pubitemid 16046307)
13. Mitjans F, Sander D, Adan J, et al. An anti-αv-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice. J Cell Sci 1995;108:2825-2838
14. Clark EA, Golub TR, Lander ES, Hynes RO. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 2000;406:532-535
15. Lal A, Lash AE, Altschul SF, et al. A public database for gene expression in human cancers. Cancer Res 1999;59:5403-5407
16. Yao ES, Zhang H, Chen YY, et al. Increased β1 integrin is associated with decreased survival in invasive breast cancer. Cancer Res 2007; 67:659-664
17. Sakai T, Johnson KJ, Murozono M, et al. Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat Med 2001;7:324-330
18. Ahn HS, Foster C, Boykow G, Stamford A, Manna M, Graziano M. Inhibition of cellular action of thrombin by N3-cyclopropyl-7-4-(1-methylethyl)phenyl] methyl]-7H-pyrrolo[3, 2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist. Biochem Pharmacol 2000;60:1425-1434
19. Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE. SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. Basic Res Cardiol 2007;102:350-358
20. Ruoslahti E, Hayman EG, Pierschbacher M, Engvall E. Fibronectin: purification, immunochemical properties, and biological activities. Methods Enzymol 1982;82:803-831
21. Corbett SA, Wilson CL, Schwarzbauer JE. Changes in cell spreading and cytoskeletal organization are induced by adhesion to a fibronectin-fibrin matrix. Blood 1996;88:158-166
22. Matikainen S, Hurme M. Comparison of retinoic acid and phorbol myristate acetate as inducers of monocytic differentiation. Int J Cancer 1994;57:98-103. (Pubitemid 24117107)
23. Pampori N, Hato T, Stupack DG, et al. Mechanisms and consequences of affinity modulation of integrin α(V)β(3) detected with a novel patch-engineered monovalent ligand. J Biol Chem 1999;274: 21609-21616
24. Palumbo JS, Kombrinck KW, Drew AF, et al. Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells. Blood 2000;96:3302-3309
25. Avraamides CJ, Garmy-Susini B, Varner JA. Integrins in angiogenesis and lymphangiogenesis. Nat Rev Cancer 2008;8:604-617
26. Barkan D, Kleinman H, Simmons JL, et al. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res 2008;68:6241-6250
27. Honn KV, Tang DG, Grossi IM, et al. Enhanced endothelial cell retraction mediated by 12(S)-HETE: a proposed mechanism for the role of platelets in tumor cell metastasis. Exp Cell Res 1994;210:1-9.
28. Hu L, Lee M, Campbell W, Perez-Soler R, Karpatkin S. Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis. Blood 2004;104:2746-2751
29. Palumbo JS, Potter JM, Kaplan LS, Talmage K, Jackson DG, Degen JL. Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice. Cancer Res 2002;62:6966-6972 (Pubitemid 35424088)
30. Bruggemann LW, Versteeg HH, Niers TM, Reitsma PH, Spek CA. Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders. J Cell Mol Med 2008;12:2622-2627
31. Klerk CP, Smorenburg SM, Spek CA, Van Noorden CJ. Colon cancer metastasis in mouse liver is not affected by hypercoagulability due to factor V Leiden mutation. J Cell Mol Med 2007;11:561-568
32. Rosenow F, Ossig R, Thormeyer D, et al. Integrins as antimetastatic targets of RGD-independent snake venom components in liver metastasis [corrected]. Neoplasia 2008;10:168-176
33. Zhang J, Nakayama J, Ohyama C, et al. Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin. Cancer Res 2002;62:4194-4198 (Pubitemid 34827270)
34. Lai CS, Wolff CE, Novello D, et al. Solution structure of human plasma fibronectin under different solvent conditions. Fluorescence energy transfer, circular dichroism and light-scattering studies. J Mol Biol 1993;230:625-640
35. Chen YP, O'Toole TE, Leong L, Liu BQ, Diaz-Gonzalez F, Ginsberg MH. β3 integrin-mediated fibrin clot retraction by nucleated cells: differing behavior of αIIbβ3 and αvβ3. Blood 1995;86:2606-2615
36. Pilch J, Habermann R, Felding-Habermann B. Unique ability of integrin α(v)β3 to support tumor cell arrest under dynamic flow conditions. J Biol Chem 2002;277:21930-21938
37. Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999;285: 1028-1032
38. Morla A, Zhang Z, Ruoslahti E. Superfibronectin is a functionally distinct form of fibronectin. Nature 1994;367:193-196
39. Alon R, Cahalon L, Hershkoviz R, et al. TNF-α binds to the N-terminal domain of fibronectin and augments the β1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein. J Immunol 1994; 152:1304-1313 (Pubitemid 24134358)
40. Banno A, Ginsberg MH. Integrin activation. Biochem Soc Trans 2008;36:229-234
41. Byzova TV, Goldman CK, Pampori N, et al. A mechanism for modulation of cellular responses to VEGF: activation of the integrins. Mol Cell 2000;6:851-860
42. Dormond O, Bezzi M, Mariotti A, Ruegg C. Prostaglandin E2 promotes integrin αVβ3-dependent endothelial cell adhesion, racactivation, and spreading through cAMP/PKA-dependent signaling. J Biol Chem 2002;277:45838-45846
43. Nierodzik ML, Klepfish A, Karpatkin S. Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo. Thromb Haemost 1995;74: 282-290
44. Pelletier AJ, van der Laan LJ, Hildbrand P, et al. Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells. Blood 2000;96:2682-2690
45. Cheng HC, Abdel-Ghany M, Pauli BU. A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis. J Biol Chem 2003;278:24600-24607
46. Essex DW, Li M. Protein disulphide isomerase mediates platelet aggregation and secretion. Br J Haematol 1999;104:448-454 (Pubitemid 29119264)
47. Inamoto T, Yamochi T, Ohnuma K, et al. Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kip1) enhancement, and disruption of binding to the extracellular matrix. Clin Cancer Res 2006;12:3470-3477
48. Jalkanen S, Jalkanen M. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin. J Cell Biol 1992; 116:817-825
49. Langenbach KJ, Sottile J. Identification of protein-disulfide isomerase activity in fibronectin. J Biol Chem 1999;274:7032-7038 (Pubitemid 129504987)
50. Lee JL, Wang MJ, Sudhir PR, Chen GD, Chi CW, Chen JY. Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells. Cancer Res 2007;67:2089-2097