Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27kip1 enhancement, and disruption of binding to the extracellular matrix

Clinical Cancer Research

Volumn 12, Issue 11 I, 2006, Pages 3470-3477

  Inamoto, Teruo ^a,c   Yamochi, Tadanori ^a   Ohnuma, Kei ^a   Iwata, Satoshi ^a   Kina, Shinichiro ^a   Inamoto, Sakiko ^a,c   Tachibana, Masaaki ^b   Katsuoka, Yoji ^c   Dang, Nam H ^d   Morimoto, Chikao ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d NEVADA CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CELL SURFACE PROTEIN; COLLAGEN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DIPEPTIDYL PEPTIDASE IV; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD26; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL SURVIVAL; CLEAR CELL CARCINOMA; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RETINOBLASTOMA;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, CD26; BINDING SITES; CARCINOMA, RENAL CELL; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; EXTRACELLULAR MATRIX; FEMALE; G1 PHASE; HUMANS; KIDNEY NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN; S PHASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPLANTATION, HETEROLOGOUS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 33745206673     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-0361     Document Type: Article

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