Synthesis of water-soluble polyamine derivatives effective as N-methyl-D-aspartate receptor antagonists

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 6, 2010, Pages 862-867

  Masuko, Takashi ^a   Yoshida, Shuhei ^a   Metori, Koichi ^a   Kizawa, Yasuo ^a   Kusama, Tadashi ^a   Miyake, Muneharu ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

N methyl D aspartate receptor; Polyamine; Voltage clamp recording; Xenopus oocyte

Indexed keywords

GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N [3 [4 (3 GUANIDINOPROPYLAMINO)BUTYLAMINO]PROPYL] 4 TOLUENESULFONAMIDE; N [3 [4 (3 GUANIDINOPROPYLAMINO)BUTYLAMINO]PROPYL]BUTANE 1 SULFONAMIDE; N [4 [4 (4 GUANIDINOBUTYLAMINO)BUTYLAMINO]BUTYL] 4 TOLUENESULFONAMIDE; N [4 [4 (4 GUANIDINOBUTYLAMINO)BUTYLAMINO]BUTYL]BUTANE 1 SULFONAMIDE; SPERMINE; UNCLASSIFIED DRUG; POLYAMINE; WATER;

ANIMAL CELL; ARTICLE; DRUG EFFECT; DRUG SYNTHESIS; FEMALE; NONHUMAN; OOCYTE; PROTEIN EXPRESSION; VOLTAGE CLAMP; XENOPUS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; PATCH CLAMP TECHNIQUE; SOLUBILITY; SYNTHESIS;

ANIMALS; GENE EXPRESSION; OOCYTES; PATCH-CLAMP TECHNIQUES; POLYAMINES; RECEPTORS, N-METHYL-D-ASPARTATE; SOLUBILITY; WATER; XENOPUS;

EID: 77953140612     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.862     Document Type: Article

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