Design and synthesis of a novel water-soluble NMDA receptor antagonist with a 1,4,7,10-tetraazacyclododecane group

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 4, 2005, Pages 444-447

  Masuko, Takashi ^a   Metori, Koichi ^a   Kizawa, Yasuo ^a   Kusama, Tadashi ^a   Miyake, Muneharu ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

1,4,7,10 tetraazacyclododecane; N methyl D aspartate (NMDA) receptor; Xenopus oocytes

Indexed keywords

2,8 BIS[(1,4,7,10 TETRAAZACYCLODODECAN 1 YL)OXOMETHYL] 6H,12H 5,11 METHANODIBENZO[B,F][1,5]DIAZOCINE; 4 AMINOBUTYRIC ACID; 4,4' BIS[2 (1,4,7,10 TETRAAZACYCLODECAN 1 YL)ACETYLAMINOETHOXY]DIPHENYLMETHANE; DODECANE; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POLYAMINE; RECEPTOR SUBTYPE; SPERMINE; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; FEMALE; MASS SPECTROMETRY; NONHUMAN; VOLTAGE CLAMP; XENOPUS;

ANIMALS; EXCITATORY AMINO ACID ANTAGONISTS; HETEROCYCLIC COMPOUNDS; INDICATORS AND REAGENTS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, N-METHYL-D-ASPARTATE; XENOPUS;

EID: 21144450848     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.444     Document Type: Article

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