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Volumn 18, Issue 12, 2010, Pages 4167-4177
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Discovery of tetrahydro-β-carbolines as inhibitors of the mitotic kinesin KSP
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Author keywords
Anti proliferation; Inhibitor; Kinesin spindle protein; KSP; Mitotic kinesin; Tetrahydro carboline
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Indexed keywords
1 (3 HYDROXYPHENYL) 2 (4 AMINOBENZYL) 6 CHLORO 1,2,3,4 TETRAHYDRO BETA CARBOLINE;
1 (3 HYDROXYPHENYL) 2 (ALPHA AMINOPROPIONYL) 6 CHLORO 1,2,3,4 TETRAHYDRO BETA CARBOLINE;
6 METHYL 1 (INDOL 3 YL) 2 BUTYRYL 1,2,3,4 TETRAHYDRO BETA CARBOLINE;
ANTINEOPLASTIC AGENT;
CK 0106023;
HR 22C16;
KINESIN SPINDLE PROTEIN;
PROTEIN;
PROTEIN INHIBITOR;
TRYPTOLINE DERIVATIVE;
UNCLASSIFIED DRUG;
1-(3-HYDROXYPHENYL)-2-(4-AMINOBENZOYL)-6-CHLORO-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE;
1-(3-HYDROXYPHENYL)-2-(BETA-AMINOPROPIONYL)-8-CHLORO-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE;
6-METHYL-1-(INDOL-3-YL)-2-BUTYRYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE;
CARBOLINE DERIVATIVE;
ENZYME INHIBITOR;
HR22C16;
INDOLE DERIVATIVE;
KINESIN;
PHENOL DERIVATIVE;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG IDENTIFICATION;
DRUG POTENCY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME ASSAY;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
MITOSIS INHIBITION;
MITOSIS SPINDLE;
STRUCTURE ANALYSIS;
ANTAGONISTS AND INHIBITORS;
CHEMISTRY;
DRUG DEVELOPMENT;
ENZYMOLOGY;
METABOLISM;
SPINDLE APPARATUS;
SYNTHESIS;
TUMOR CELL LINE;
ANTINEOPLASTIC AGENTS;
CARBOLINES;
CELL LINE, TUMOR;
DRUG DISCOVERY;
DRUG SCREENING ASSAYS, ANTITUMOR;
ENZYME INHIBITORS;
HUMANS;
INDOLES;
KINESIN;
MITOTIC SPINDLE APPARATUS;
PHENOLS;
SPINDLE APPARATUS;
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EID: 77953132117
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2010.05.024 Document Type: Article |
Times cited : (34)
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References (17)
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