Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 11, 2010, Pages 4119-4137

  Lamblin, Marc ^a   Dabbas, Basel ^a   Spingarn, Russell ^a   Mendoza Sanchez, Rodrigo ^a   Wang, Tian Tian ^a   An, Beum Soo ^a   Huang, Dao Chao ^a   Kremer, Richard ^a   White, John H ^a   Gleason, James L ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Dual pharmacophores; HDAC inhibitors; Histone deacetylases (HDACs); Hybrid molecules; Transcriptional regulation; VDR agonists; Vitamin D; Vitamin D receptor (VDR); Zinc binding groups

Indexed keywords

CALCITRIOL; ZINC BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; FEMALE; HYPERCALCEMIA; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR HYBRIDIZATION; MOUSE; NONHUMAN; SQUAMOUS CELL CARCINOMA; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; HISTONE DEACETYLASE INHIBITORS; HUMANS; RECEPTORS, CALCITRIOL; VITAMIN D; ZINC;

EID: 77953129939     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.03.078     Document Type: Article

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