Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 10, 2010, Pages 3387-3402

  Büttner, Anita ^a   Cottin, Thomas ^a   Xu, Jing ^a   Tzagkaroulaki, Lito ^a   Giannis, Athanassios ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Carbazole; Inhibitor; Receptor tyrosine kinases; Serotonin

Indexed keywords

2 [5 (4 HYDROXYPHENETHOXY) 1 (4 METHOXYPHENYL)BENZYL 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 HYDROXYPHENETHOXY) 1 (4 PHENYL)BENZYL 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 HYDROXYPHENETHOXY) 1 [4 (3 TRIFLUOROMETHYLPHENYL)]BENZYL 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 HYDROXYPHENETHOXY) 1 [5 (4 METHOXYPHENYL)PENTYL] 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 HYDROXYPHENETHOXY) 1 [5 [4 (METHYLTHIO)PHENYL]PENTYL] 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 HYDROXYPHENETHOXY) 1H INDOLE 3 YL]ETHANAMINE; 2 [5 (4 METHOXYPHENETHOXY) 1 [5 [4 (METHYLTHIO)PHENYL]PENTYL] 1H INDOLE 3 YL]ETHANAMINE; 4 (2 METHOXYETHYL)PHENOL; 4 [2 (3 AMINO 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY)ETHYL]PHENOL; 4 [2 [3 AMINO 9 (3 PHENYLPROPYL) 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY]ETHYL]PHENOL; 4 [2 [3 AMINO 9 [5 (4 METHOXYPHENYL)PENTYL] 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY]ETHYL]PHENOL; 4 [2 [3 AMINO 9 [5 (PYRIDINE 2 YL)PENTYL] 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY]ETHYL]PHENOL; 4 [2 [3 AMINO 9 [5 [4 (DIMETHYLAMINO)PHENYL]PENTYL] 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY]ETHYL]PHENOL; 4 [2 [3 AMINO 9 [5 [4 (TRIFLUOROMETHYL)PHENYL]PENTYL] 2,3,4,9 TETRAHYDRO 1H TETRAHYDROCARBAZOLE 6 YLOXY]ETHYL]PHENOL; ADENOSINE TRIPHOSPHATE; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; SEROTONIN; SEROTONIN DERIVATIVE; SOMATOMEDIN C RECEPTOR; TERT BUTYL 2 [5 (4 HYDROXYPHENETHOXY) 1 [5 [4 (METHYLTHIO)PHENYL]PENTYL] 1H INDOLE 3 YL]ETHYL CARBAMATE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

ALLOSTERISM; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; MITOSIS INHIBITION; UMBILICAL VEIN;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; HUMANS; PROTEIN KINASE INHIBITORS; RECEPTOR PROTEIN-TYROSINE KINASES; SEROTONIN; TUMOR CELLS, CULTURED;

EID: 77953126861     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.04.001     Document Type: Article

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