Development and characterization of a three-dimensional organotypic human vaginal epithelial cell model

Biology of Reproduction

Volumn 82, Issue 3, 2010, Pages 617-627

  Hjelm, Brooke E ^a,b,c   Berta, Alice N ^a   Nickerson, Cheryl A ^a,b   Arntzen, Charles J ^a,b   Herbst Kralovetz, Melissa M ^a,d  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

3 D organotypic model; Cytokines; Female reproductive tract; Immunology; Innate immunology; Pathogen associated molecular patterns (PAMPs); Rotating wall vessel (RWV) bioreactor; Toll like receptors (TLRs); Vagina; Vaginal microbicide screening

Indexed keywords

MUCIN 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; CYTOKINE; MUCIN; NONOXINOL; SPERMICIDAL AGENT; TISSUE SCAFFOLD; TOLL LIKE RECEPTOR;

ARTICLE; BIOREACTOR; CELL INTERACTION; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; THREE DIMENSIONAL IMAGING; TRANSMISSION ELECTRON MICROSCOPY; VAGINA EPITHELIUM; BIOLOGICAL MODEL; CELL CULTURE; COMPARATIVE STUDY; CULTURE TECHNIQUE; CYTOLOGY; DRUG SCREENING; EPITHELIUM CELL; EVALUATION; FEMALE; METABOLISM; METHODOLOGY; ORGAN CULTURE TECHNIQUE; THEORETICAL MODEL; TISSUE ENGINEERING; ULTRASTRUCTURE; VAGINA;

ANIMALIA;

CELL CULTURE TECHNIQUES; CELLS, CULTURED; CYTOKINES; DRUG EVALUATION, PRECLINICAL; EPITHELIAL CELLS; FEMALE; HUMANS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; MUCINS; NONOXYNOL; ORGAN CULTURE TECHNIQUES; SPERMATOCIDAL AGENTS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TOLL-LIKE RECEPTORS; VAGINA;

EID: 77953116144     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.080408     Document Type: Article

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