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Volumn 24, Issue 3, 2010, Pages 341-348

Asenapine induces differential regional effects on serotonin receptor subtypes

Author keywords

Asenapine; Caudate putamen; Frontal cortex; Hippocampus; Serotonin receptor

Indexed keywords

ASENAPINE; OLANZAPINE; QUETIAPINE; RISPERIDONE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN RECEPTOR; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; FUSED HETEROCYCLIC RINGS; NEUROLEPTIC AGENT;

EID: 77953076000     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881108095704     Document Type: Article
Times cited : (34)

References (51)
  • 2
    • 0035007327 scopus 로고    scopus 로고
    • GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder
    • Benes, FM, Berretta, S (2001) GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25: 1-27.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 1-27
    • Benes, F.M.1    Berretta, S.2
  • 4
    • 0029891621 scopus 로고    scopus 로고
    • The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain
    • Burnet, PW, Chen, CP, McGowan, S, Franklin, M, Harrison, PJ (1996) The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain. Neuroscience 73: 531-540.
    • (1996) Neuroscience , vol.73 , pp. 531-540
    • Burnet, P.W.1    Chen, C.P.2    McGowan, S.3    Franklin, M.4    Harrison, P.J.5
  • 7
    • 0030980673 scopus 로고    scopus 로고
    • Dopamine receptor subtypes: Differential regulation after 8 months treatment with antipsychotic drugs
    • Florijn, WJ, Tarazi, FI, Creese, I (1997) Dopamine receptor subtypes: differential regulation after 8 months treatment with antipsychotic drugs. J Pharmacol Exp Ther 250: 561-569.
    • (1997) J Pharmacol Exp Ther , vol.250 , pp. 561-569
    • Florijn, W.J.1    Tarazi, F.I.2    Creese, I.3
  • 9
    • 0026612799 scopus 로고
    • 5-HydroxytryptaminelA but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin
    • Francis, PT, Pangalos, MN, Pearson, RC, Middlemiss, DN, Stratmann, GC, Bowen, DM (1992) 5-HydroxytryptaminelA but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin. J Pharmacol Exp Ther 261: 1273-1281.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 1273-1281
    • Francis, P.T.1    Pangalos, M.N.2    Pearson, R.C.3    Middlemiss, D.N.4    Stratmann, G.C.5    Bowen, D.M.6
  • 10
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman, AG (1987) G proteins: transducers of receptor-generated signals. Annu Rev Biochem 56: 615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 11
    • 0004296209 scopus 로고    scopus 로고
    • fourth ed. Upper Saddle River, NJ: Prentice Hall
    • Greene, WH (2000) Econometric Analysis, fourth ed. Upper Saddle River, NJ: Prentice Hall, pp 462-465.
    • (2000) Econometric Analysis , pp. 462-465
    • Greene, W.H.1
  • 12
    • 0030825125 scopus 로고    scopus 로고
    • Alterations in the cortical serotonergic system in schizophrenia: A postmortem study
    • Gurevich, EV, Joyce, JN (1997) Alterations in the cortical serotonergic system in schizophrenia: a postmortem study. Biol Psychiatry 42: 529-545.
    • (1997) Biol Psychiatry , vol.42 , pp. 529-545
    • Gurevich, E.V.1    Joyce, J.N.2
  • 15
    • 53949102049 scopus 로고    scopus 로고
    • Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus
    • (Epub ahead of print, April 16)
    • Huang, M, Li, Z, Dai, J, Shahid, M, Wong, EF, Meltzer, HY (2008) Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus. Neuropsychopharmacology (Epub ahead of print, April 16).
    • (2008) Neuropsychopharmacology
    • Huang, M.1    Li, Z.2    Dai, J.3    Shahid, M.4    Wong, E.F.5    Meltzer, H.Y.6
  • 17
    • 34047130777 scopus 로고    scopus 로고
    • Schizophrenia: New pathological insights and therapies
    • DOI 10.1146/annurev.med.58.060904.084114
    • Jarskog, LF, Miyamoto, S, Lieberman, JA (2007) Schizophrenia: new pathological insights and therapies. Annu Rev Med 58: 49-61. (Pubitemid 46706500)
    • (2007) Annual Review of Medicine , vol.58 , pp. 49-61
    • Jarskog, L.F.1    Miyamoto, S.2    Lieberman, J.A.3
  • 18
    • 0027279038 scopus 로고
    • Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics
    • Joyce, JN, Shane, A, Lexow, N, Winokur, A, Casanova, MF, Kleinman, JE (1993) Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology 8: 315-336. (Pubitemid 23162958)
    • (1993) Neuropsychopharmacology , vol.8 , Issue.4 , pp. 315-336
    • Joyce, J.N.1    Shane, A.2    Lexow, N.3    Winokur, A.4    Casanova, M.F.5    Kleinman, J.E.6
  • 19
    • 33244462829 scopus 로고    scopus 로고
    • How antipsychotics work - From receptors to reality
    • DOI 10.1016/j.nurx.2005.12.003
    • Kapur, S, Agid, O, Mizrahi, R, Li, M (2006) How antipsychotics work-from receptors to reality. NeuroRx 3: 10-21. (Pubitemid 43276632)
    • (2006) NeuroRx , vol.3 , Issue.1 , pp. 10-21
    • Kapur, S.1    Agid, O.2    Mizrahi, R.3    Li, M.4
  • 22
    • 0023255094 scopus 로고
    • Differential regulation of dopamine-D2 and serotonin-S2 receptors by chronic treatment with the serotonin-S2 antagonists, ritanserin, and setoperone
    • Leysen, JE, van Gompel, P, Gommeren, W, Laduron, PM (1987) Differential regulation of dopamine-D2 and serotonin-S2 receptors by chronic treatment with the serotonin-S2 antagonists, ritanserin, and setoperone. Psychopharmacol Ser 3: 214-224.
    • (1987) Psychopharmacol ser , vol.3 , pp. 214-224
    • Leysen, J.E.1    Van Gompel, P.2    Gommeren, W.3    Laduron, P.M.4
  • 23
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drag action
    • Meltzer, HY (1999) The role of serotonin in antipsychotic drag action. Neuropsychopharmacology 21: 106S-115S.
    • (1999) Neuropsychopharmacology , vol.21
    • Meltzer, H.Y.1
  • 24
    • 0026357347 scopus 로고
    • Effects of antipsychotic drugs on serotonin receptors
    • Meltzer, HY, Nash, JF (1991) Effects of antipsychotic drugs on serotonin receptors. Pharmacol Rev 43: 587-604.
    • (1991) Pharmacol Rev , vol.43 , pp. 587-604
    • Meltzer, H.Y.1    Nash, J.F.2
  • 26
    • 0025336772 scopus 로고
    • 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution
    • 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution. Neuroscience 35: 577-591.
    • (1990) Neuroscience , vol.35 , pp. 577-591
    • Mengod, G.1    Nguyen, H.2    Le, H.3    Waeber, C.4    Lubbert, H.5    Palacios, J.M.6
  • 28
    • 0022930993 scopus 로고
    • Decreased serotonin. S2 and increased dopamine D2 receptors in chronic schizophrenics
    • Mita, T, Hanada, S, Nishino, N, Kuno, T, Nakai, H, Yamadori, T, et al. (1986) Decreased serotonin. S2 and increased dopamine D2 receptors in chronic schizophrenics. Biol Psychiatry 21: 1407-1414.
    • (1986) Biol Psychiatry , vol.21 , pp. 1407-1414
    • Mita, T.1    Hanada, S.2    Nishino, N.3    Kuno, T.4    Nakai, H.5    Yamadori, T.6
  • 29
    • 34548635124 scopus 로고    scopus 로고
    • Comparison of the efficacy of asenapine, risperidone, and olanzapine to improve a reversal learning deficit in the rat
    • Neill, JC, Shahid, M, Wong, EHF, Idris, NF (2006) Comparison of the efficacy of asenapine, risperidone, and olanzapine to improve a reversal learning deficit in the rat. Schizophr Res 81: 105-106.
    • (2006) Schizophr Res , vol.81 , pp. 105-106
    • Neill, J.C.1    Shahid, M.2    Wong, E.H.F.3    Idris, N.F.4
  • 30
    • 14844344472 scopus 로고    scopus 로고
    • Metabolic risk during antipsychotic treatment
    • Newcomer, JW (2004) Metabolic risk during antipsychotic treatment. Clin Ther 26: 1936-1946.
    • (2004) Clin Ther , vol.26 , pp. 1936-1946
    • Newcomer, J.W.1
  • 31
    • 0025167982 scopus 로고
    • Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain
    • O'Dell, SJ, La Hoste, GJ, Widmark, CB, Shapiro, RM, Potkin, SG, Marshall, JF (1990) Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain. Synapse 6: 146-153.
    • (1990) Synapse , vol.6 , pp. 146-153
    • O'Dell, S.J.1    La Hoste, G.J.2    Widmark, C.B.3    Shapiro, R.M.4    Potkin, S.G.5    Marshall, J.F.6
  • 32
    • 0027234989 scopus 로고
    • The role of serotonin in schizophrenia: An overview of the nomenclature, distribution and alterations of serotonin receptors in the central nervous system
    • Ohuoha, DC, Hyde, TM, Kleinman, JE (1993) The role of serotonin in schizophrenia: an overview of the nomenclature, distribution and alterations of serotonin receptors in the central nervous system. Psychopharmacology (Berl) 112: S5-S15.
    • (1993) Psychopharmacology (Berl) , vol.112
    • Ohuoha, D.C.1    Hyde, T.M.2    Kleinman, J.E.3
  • 33
    • 0022346190 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
    • Pazos, A, Palacios, JM (1985) Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res 346: 205-230.
    • (1985) Brain Res , vol.346 , pp. 205-230
    • Pazos, A.1    Palacios, J.M.2
  • 34
    • 0026565253 scopus 로고
    • 1A receptor in the rat brain: Correlation with receptor binding
    • 1A receptor in the rat brain: correlation with receptor binding. J Neurosci 12: 440-453.
    • (1992) J Neurosci , vol.12 , pp. 440-453
    • Pompeiano, M.1    Palacios, J.M.2    Mengod, G.3
  • 35
    • 35948982974 scopus 로고    scopus 로고
    • Efficacy and tolerability of asenapine in acute schizophrenia: A placebo- And risperidonecontrolled trial
    • Potkin, SG, Cohen, M, Panagides, J (2007) Efficacy and tolerability of asenapine in acute schizophrenia: a placebo- and risperidonecontrolled trial, J Clin Psychiatry 68: 1492-1500.
    • (2007) J Clin Psychiatry , vol.68 , pp. 1492-1500
    • Potkin, S.G.1    Cohen, M.2    Panagides, J.3
  • 39
    • 3142704173 scopus 로고    scopus 로고
    • Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders
    • Roth, BL, Hanizavareh, SM, Blum, AE (2004) Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders. Psychopharmacology (Berl) 174: 17-24.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 17-24
    • Roth, B.L.1    Hanizavareh, S.M.2    Blum, A.E.3
  • 41
    • 43049146626 scopus 로고    scopus 로고
    • Asenapine: A novel psychopharmacologic agent with a unique human receptor signature
    • (Epub ahead of print, February 28)
    • Shahid, M, Walker, GB, Zorn, SH, Wong, EHF (2008) Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol (Epub ahead of print, February 28).
    • (2008) J Psychopharmacol
    • Shahid, M.1    Walker, G.B.2    Zorn, S.H.3    Wong, E.H.F.4
  • 45
    • 0035038086 scopus 로고    scopus 로고
    • Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: Implications for antipsychotic drag treatment
    • Tarazi, FI, Zhang, K, Baldessarini, RJ (2001) Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drag treatment. J Pharmacol Exp Ther 297: 711-717.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 711-717
    • Tarazi, F.I.1    Zhang, K.2    Baldessarini, R.J.3
  • 46
    • 0035991065 scopus 로고    scopus 로고
    • Long-term effects of olanzapine, risperidone, and quetiapine on serotonin 1A, 2A and 2C receptors in rat forebrain regions
    • Tarazi, FI, Zhang, K, Baldessarini, RJ (2002) Long-term effects of olanzapine, risperidone, and quetiapine on serotonin 1A, 2A and 2C receptors in rat forebrain regions. Psychopharmacology (Berl) 161: 263-270.
    • (2002) Psychopharmacology (Berl) , vol.161 , pp. 263-270
    • Tarazi, F.I.1    Zhang, K.2    Baldessarini, R.J.3
  • 47
    • 0036180418 scopus 로고    scopus 로고
    • Effects of newer antipsychotics on extrapyramidal function
    • Tarsy, D, Baldessarini, RJ, Tarazi, FI (2002) Effects of newer antipsychotics on extrapyramidal function. CNS Drugs 16: 23-45. (Pubitemid 34151336)
    • (2002) CNS Drugs , vol.16 , Issue.1 , pp. 23-45
    • Tarsy, D.1    Baldessarini, R.J.2    Tarazi, F.I.3
  • 51
    • 0028985633 scopus 로고
    • Comparative localization of serotonin 1A, 1C, and 2 receptor subtype mRNAs in rat brain
    • Wright, DE, Seroogy, KB, Lundgren, KH, Davis, BM, Jennes, L (1995) Comparative localization of serotonin 1A, 1C, and 2 receptor subtype mRNAs in rat brain. J Comp Neurol 351: 357-373.
    • (1995) J Comp Neurol , vol.351 , pp. 357-373
    • Wright, D.E.1    Seroogy, K.B.2    Lundgren, K.H.3    Davis, B.M.4    Jennes, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.