The PtdIns(3,4)P 2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

Nature

Volumn 465, Issue 7297, 2010, Pages 497-501

  Sasaki, Junko ^a,b   Kofuji, Satoshi ^a,b   Itoh, Reietsu ^a,b   Momiyama, Toshihiko ^c   Takayama, Kiyohiko ^b,d   Murakami, Haruka ^a,b   Chida, Shinsuke ^a,b   Tsuya, Yuko ^a,b   Takasuga, Shunsuke ^a,b   Eguchi, Satoshi ^a,b   Asanuma, Ken ^a,b   Horie, Yasuo ^a   Miura, Kouichi ^a   Davies, Elizabeth Michele ^e   Mitchell, Christina ^e   Yamazaki, Masakazu ^b   Hirai, Hirokazu ^b,d   Takenawa, Tadaomi ^f   Suzuki, Akira ^b,g   Sasaki, Takehiko ^a,b  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e MONASH UNIVERSITY   (Australia)

^f KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; INOSITOL POLYPHOSPHATE PHOSPHATASE 4A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

APOPTOSIS; COGNITION; DISEASE TREATMENT; ENZYME ACTIVITY; ETIOLOGY; MEDICINE; METABOLISM; NERVOUS SYSTEM DISORDER; PHOSPHOLIPID; PHYSIOLOGY; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN DEGENERATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ANALYSIS; EXCITOTOXICITY; FEMALE; GENE DISRUPTION; GENE SILENCING; INVOLUNTARY MOVEMENT; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; DYSKINESIAS; GLUTAMIC ACID; HUMANS; MICE; MICE, INBRED C57BL; NEOSTRIATUM; NEURODEGENERATIVE DISEASES; NEURONS; PHOSPHORIC MONOESTER HYDROLASES; RECEPTORS, N-METHYL-D-ASPARTATE; SURVIVAL RATE; SYNAPSES; WEIGHT LOSS;

MUS;

EID: 77953027360     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09023     Document Type: Article

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