Biclonal chronic lymphocytic leukemia

American Journal of Clinical Pathology

Volumn 113, Issue 6, 2000, Pages 798-804

  Hsi, E D ^a   Hoeltge, G ^a   Tubbs, R R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Biclonal; Cell sorting; Chronic lymphocytic leukemia; Flow cytometry; Gene rearrangement

Indexed keywords

CD19 ANTIGEN; CD23 ANTIGEN; CD5 ANTIGEN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

AGED; ARTICLE; B LYMPHOCYTE; CASE REPORT; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL FEATURE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTOSIS; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

AGED; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTE SUBSETS; BLOTTING, SOUTHERN; CLONE CELLS; DNA, NEOPLASM; FLOW CYTOMETRY; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOPHENOTYPING; KARYOTYPING; LEUKEMIA, B-CELL, CHRONIC; MALE; POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 0034502262     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/V8AN-A2XP-7TDV-HR0T     Document Type: Article

References (28)

1. National Cancer Institute - Sponsored working group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
2. The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL
3. Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b)
4. Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions
5. Monoclonality in B cell lymphoma detected in paraffin wax embedded sections using the polymerase chain reaction
6. Detection of immunoglobulin heavy chain gene rearrangement by polymerase chain reaction in chronic active gastritis associated with Helicobacter pylori
7. Reduced expression of CD20 antigen as a characteristic marker for chronic lymphocytic leukemia
8. Expression of the immunoglobulin-associated protein B29 in B cell disorders with the monoclonal antibody SN8 (CD79b)
9. Chronic lymphocytic leukemia with two cellular populations: A biphenotypic or biclonal disease
10. Biclonal B-cell chronic lymphocytic leukemia with inv (14) (q11q32)
11. Oligoclonal B-cell leukemia characterized by spontaneous cell division and telomere association
12. Four aged siblings with B cell chronic lymphocytic leukemia
13. Aberrant CD8 antigen expression in a patient with B chronic lymphocytic leukaemia showing unusual disease progression
14. Immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukaemia: Correlation with clinical stage
15. Karyotypic evolution in CLL: Identification of a new sub-group of patients with deletions of 11q and advanced or progressive disease
16. Analysis of immunoglobulin and T cell receptor genes, II: Possibilities and limitations in the diagnosis and management of lymphoproliferative diseases and related disorders
17. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
18. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
19. Immunoglobulin genes in chronic lymphocytic leukemia
20. Alterations in immunoglobulin genes reveal the origin and evolution of monotypic and bitypic B cell lymphomas
21. Mutational status of Ig V(H) genes provides clinically valuable information in B-cell chronic lymphocytic leukemia
22. Persistent polyclonal lymphocytosis with binucleated B lymphocytes: A genetic predisposition
23. All patients with persistent polyclonal B cell lymphocytosis present Bcl-2/Ig gene rearrangements
24. Polyclonal CD5+ B-lymphocytosis resembling chronic lymphocytic leukaemia
25. CD5+ persistent polyclonal B-cell lymphocytosis in a male
26. Increased incidence of HLA antigen B35 in patients with chronic lymphocytic leukemia
27. Increased incidence of hematologic malignancies in first-degree relatives of patients with chronic lymphocytic leukemia
28. Familial chronic lymphocytic leukemia